Perioperative outcome of laparoscopic left lateral liver resection is improved by using a bioabsorbable staple line reinforcement material in a porcine model

Hypothesis Laparoscopic liver surgery is significantly limited by the technical difficulty encountered during transection of substantial liver parenchyma, with intraoperative bleeding and bile leaks. This study tested whether the use of a bioabsorble staple line reinforcement material would improve outcome during stapled laparoscopic left lateral liver resection in a porcine model. Study design A total of 20 female pigs underwent stapled laparoscopic left lateral liver resection. In group A (n = 10), the stapling devices were buttressed with a bioabsorbable staple line reinforcement material. In group B (n = 10), standard laparoscopic staplers were used. Operative data and perioperative complications were recorded. Necropsy studies and histopathological analysis were performed at 6 weeks. Data were compared between groups with the Student's t-test or the chi-square test. Results Operating time was similar in the two groups (64 +/- 11 min in group A versus 68 +/- 9 min in group B, p = ns). Intraoperative blood loss was significantly higher in group B (185 +/- 9 mL versus 25 +/- 5 mL, p <0.05). There was no mortality. There was no morbidity in the 6-week follow-up period; however, two animals in group B had subphrenic bilomas (20%) at necropsy. At necropsy, methylene blue injection via the main bile duct revealed leakage from the biliary tree in four animals in group B and none in group A (p <0.05). Histopathological examination of the resection site revealed minor abnormalities in group A while animals in group B demonstrated marked fibrotic changes and damaged vascular and biliary endothelium. Conclusion Use of a bioabsorbable staple line reinforcement material reduces intraoperative bleeding and perioperative bile leaks during stapled laparoscopic left lateral liver resection in a porcine model

Initial experience of laparoscopic resection of adrenal tumours

OBJECTIVE: To report our initial experience with laparoscopic resection of adrenal masses. DESIGN: Prospective study. SETTING: Teaching hospital, France. SUBJECTS: Five consecutive patients who required adrenalectomy between May 1993 and January 1994. INTERVENTION: Adrenalectomy through four trocars with the patient semisupine and in a slight reverse Trendelenburg position. MAIN OUTCOME MEASURES: Morbidity and mortality. RESULTS: Three left and two right adrenal glands were removed in a median time of 190 minutes. The patients were all women, median age 65 years (range 57 to 71). The aetiology included non-functioning adenomas (n = 2), primary aldosteronism, Cushing's adenoma, and a metastasis from a cancer of the bladder. The median tumour size was 5.5 cm (range 3 to 9). In one patient the procedure was converted to an open operation because exposure of the gland was inadequate. The median postoperative stay was 6 days (range 4-12). CONCLUSIONS: Our initial experience supports that from other centres in that we found that the laparoscopic approach is suitable for resection of adrenal masses