Amplificación del efecto destructivo de los desprendimientos rocosos por deslizamiento sobre suelos volcánicos (Tenerife y Madeira)

This work provides geomorphological and geotechnical observations on the amplification of the destructive behaviour of rock falls developed in rocky slopes with a soil rich in organic matter, which are both exposed to high rainfall regimes. The determinant factor of this process would be related to the low geotechnical quality that the organic matter gives to the soil, which experience a sudden change in its fabric related to the dynamic load, similar to those observed in the quick clays in the fjords of Norway

Spectrometric characterization of amorphous silicon PIN detectors

During the last years, much interest has been dedicated to the use of amorphous silicon PIN diodes as particle and radiation detectors for medical applications. This work presents the spectrometric characterization of PECVD high deposition rate diodes fabricated at our laboratory, with thickness up to 17.5 μm. Results show that the studied devices detect the Am^(241) alpha particles and the medical X-rays generated by a mammograph model Senographe 700T from General Electric. Possible reasons of the observed energy losses are discussed in the lest. Using the SRIM2000 program, the transit of 5.5 MeV alpha particles through a diode was simulated, determining the optimum thickness for these particles to deposit their energy in the intrinsic layer of the diode

Cistogastrostoanastomosis laparoscópica en paciente pediátrico: reporte de un caso.

Los trastornos pancreáticos, las pancreatitis agudas de etiología biliar son infrecuentes en pediatría y más aún los pseudoquistes pancreáticos, los cuales son colecciones líquidas rodeadas por una cápsula fibrosa sin epitelio, generalmente secundario a una pancreatitis aguda. Presentamos el caso de una paciente femenina de 14 años, con antecedente de pancreatitis aguda de origen biliar hace 10 meses, que presenta dolor abdominal y una masa palpable en epigastrio. Se realizaron estudios imagenológicos, confirmando el diagnóstico de pseudoquiste pancreático y colelitiasis. Se optó por las bondades técnicas y estéticas de la laparoscopía, para esta población. Por lo cual, se realizó una cistogastroanastomosis y colecistectomía laparoscópica, con una evolución favorable. Nosotros reafirmamos que esta técnica, es un método seguro y efectivo, para el manejo de esta patología en pacientes pediátricos, y debería considerarse como primera opción, al no contar con procedimientos endoscópicos. Siendo este, el primer reporte en nuestro medio

Transferencia de conocimiento y los retos de la formación de ingenieros ante la globalización.

La transferencia de conocimiento es una máxima en la sociedad contemporánea. Ante este fenómeno, impulsado por la globalización neoliberal, se le impone a las instituciones de educación universitaria cambios radicales que apuntan a adecuar los planes de estudio a los requerimientos de la aldea global. La formación de ingenieros no puede situarse al margen de estas perspectivas curriculares, pero ha de imponer una visión humanista al quehacer científico y tecnológico. El presente trabajo se inscribe en la ruta de fortalecer la ética y la crítica en la formación de ingenieros

The Gut Microbiome in Polycystic Ovary Syndrome (PCOS) and its Association with Metabolic Traits

This work was funded by Estonian Research Council grants PUT 1371 (to E.O.), EMBO Installation grant 3573 (to E.O.) … E.O. was supported by European Regional Development Fund Project No. 15-0012 GENTRANSMED and Estonian Center of Genomics/Roadmap II project No 16-0125. S.A. was supported by the Spanish Ministry of Economy, Industry and Competitiveness (MINECO) and European Regional Development Fund (FEDER): grants RYC-2016-21199 and ENDORE (SAF2017-87526-R); and by FEDER/Junta de Andalucía-Consejería de Economía y Conocimiento: MENDO (B-CTS-500-UGR18).Purpose: Despite gut microbiome being widely studied in metabolic diseases, its role in polycystic ovary syndrome (PCOS) has been scarcely investigated. The aim of our study was to test for possible associations between gut microbiome and PCOS in late fertile age women and investigate whether changes in the gut microbiome correlate with PCOS-related metabolic parameters. Methods: We compared the 16S rRNA sequenced gut microbiome of 102 PCOS women with 201 age- and body mass index (BMI) matched non-PCOS women. Clinical and biochemical characteristics of the participants were assessed at ages 31 and 46 and analyzed in the context of gut microbiome data at the age of 46. Results: Bacterial diversity indices did not differ significantly between PCOS and controls. We identified four genera whose balance helps to differentiate between PCOS and non-PCOS. In the whole cohort, the abundance of two genera from the order Clostridiales was correlated with several PCOS-related markers. When investigating the gut microbiome composition in PCOS women with different BMI and glucose tolerance groups, prediabetic PCOS women had significantly lower alpha diversity and markedly increased abundance of genus Dorea compared to women with normal glucose tolerance. Conclusions: Our data indicate that PCOS and non-PCOS women at late fertile age with similar BMI do not signficantly differ in gut microbiota. However, there are significant microbial changes in PCOS individuals depending on their metabolic health. Further studies are needed in order to further understand these changes in more detail.Estonian Research Council grants PUT 1371EMBO Installation grant 3573European Regional Development Fund Project No. 15-0012 GENTRANSMEDEstonian Center of Genomics/Roadmap II project No 16-0125Spanish Ministry of Economy, Industry and Competitiveness (MINECO) European Regional Development Fund (FEDER) RYC-2016-21199 and ENDORE (SAF2017-87526-R)FEDER/Junta de Andalucía-Consejería de Economía y Conocimiento: MENDO (B-CTS-500-UGR18

Controlled transdermal release of antioxidant ferulate by a porous Sc(III) MOF

The Sc(III) MOF-type MFM-300(Sc) is demonstrated in this study to be stable under physiological conditions (PBS), biocompatible (to human skin cells), and an efficient drug carrier for the long-term controlled release (through human skin) of antioxidant ferulate. MFM-300(Sc) also preserves the antioxidant pharmacological effects of ferulate while enhancing the bio-preservation of dermal skin fibroblasts, during the delivery process. These discoveries pave the way toward the extended use of Sc(III)-based MOFs as drug delivery systems (DDSs)

Alternative Eco-Friendly Methods in the Control of Post-Harvest Decay of Tropical and Subtropical Fruits

The effectiveness on several fruits by the application of alternative methods against fungi is summarized in the present chapter. Several investigations have reported the efficacy of these technologies for controlling fungal infections. Currently, high post-harvest loses have been reported due to several factors such as inefficient management, lack of training for farmers, and problems with appropriate conditions for storage of fruits and vegetables. Even now, in many countries, post-harvest disease control is led by the application of chemical fungicides. However, in this time, awareness about fungi resistance, environmental, and health issues has led to the research of eco-friendly and effective alternatives for disease management. The pathogen establishment on fruits can be affected by the application of GRAS compounds like chitosan, essential oils, salts, among others; besides, their efficacy can be enhanced by their combination with other technologies like ultrasound. Thus, the applications of these alternatives are suitable approaches for post-harvest management of fruits

Uso de Biocolina® na alimentação de Ambystoma velasci pré-adultos

El anfibio Ambystoma velasci es una especie endémica de México sujeta a protección especial de acuerdo con la normatividad mexicana. Una de las estrategias de conservación es su mantenimiento en cautiverio siendo la alimentación uno de los aspectos más importantes a considerar. Por lo que, el objetivo de este trabajo fue evaluar el efecto de la adición de Biocolina® en la dieta de adultos Ambystoma velasci como un promotor de crecimiento. Se emplearon cuatro tratamientos de Biocolina® (0%, 1%, 2% y 3%), para evaluar los parámetros productivos y determinar el efecto lineal y cuadrático (P<0.05) de la adición de este suplemento al alimento. Los resultados indicaron un efecto lineal en el peso de los ajolotes tratados con alimento enriquecido con 2% de Biocolina®, así mismo el consumo de alimento se redujo con la dosis del 1% (P<0.05). La Biocolina® mejoró el peso de los ajolotes y optimizó el consumo de alimento en la dosis del 1%, por lo que se considera que este suplemento podría ser una alternativa para mejorar la calidad del alimento del ajolote y reducir los costos de producción por alimentación.The amphibian Ambystoma velasci is an endemic species of Mexico subject to special protection according to Mexican regulations. One of the conservation strategies is its maintenance in captivity, being feeding one of the most important aspects to consider. Therefore, the objective of this study was to evaluate the effect of the addition of Biocolina® in the diet of adult Ambystoma velasci as a growth promoter. Four Biocolina® treatments (0%, 1%, 2% and 3%) were used to evaluate the productive parameters and to determine the linear and quadratic (P<0.05) effect of the addition of this supplement to the feed. The results indicated a linear effect on the weight of axolotl treated with feed enriched with 2% Biocolina®, and feed consumption was reduced with the 1% dose (P<0.05). Biocolina® improved the weight of the salamanders and optimized feed consumption at the 1% dose, so it is considered that this supplement could be an alternative to improve the quality of axolotl feed and reduce production costs per feeding.O anfibio Ambystoma velasci é uma espécie endêmica do México sujeita a proteção especial de acordo com a regulamentação mexicana. Uma das estratégias de conservação é a sua manutenção em cativeiro, sendo a alimentação um dos aspetos mais importantes a ter em conta. Portanto, o objetivo deste trabalho foi avaliar o efeito da adição de Biocolina® na dieta de Ambystoma velasci adultos como promotor de crescimento. Quatro tratamentos Biocolina® (0%, 1%, 2% e 3%) foram utilizados para avaliar os parâmetros produtivos e determinar o efeito linear e quadrático (P<0,05) da adição deste suplemento à ração. Os resultados indicaram um efeito linear sobre o peso dos axolotes tratados com ração enriquecida com 2% de Biocolina®, assim como o consumo de ração foi reduzido com a dose de 1% (P<0,05). A Biocolina® melhorou o peso dos axolotes e otimizou o consumo de ração na dose de 1%, pelo que se considera que este suplemento poderá ser uma alternativa para melhorar a qualidade da alimentação dos axolotes e reduzir os custos de produção por ração

Social class, well-being, and general affectivity during the COVID-19 pandemic in Ibero-America

La actual pandemia de la COVID-19 ha supuesto un marcado incremento de las brechas sociales preexistentes. En esta investigación analizamos las relaciones de diferentes facetas de clase social con el bienestar y afectividad general a lo largo de un total de 8 países de la región cultural iberoamericana. Asimismo, también pusimos a prueba el potencial rol mediador del riesgo percibido relativo a la COVID-19 y de la eficacia colectiva percibida. Los resultados obtenidos (a) revelaron que una clase social más baja se relacionó con un menor bienestar y afecto positivo, así como con un mayor afecto negativo; (b) confirmaron que la clase social subjetiva constituye un mejor predictor del bienestar y afectividad general que el nivel educativo (i.e., indicador de clase social objetiva); y (c) mostraron que los efectos de la clase social subjetiva en el bienestar/afectividad general se daban de forma indirecta a través del riesgo percibido y la eficacia colectiva. Estos hallazgos confirman la existencia de diferencias en bienestar y afectividad general en función de la clase social durante la pandemia, al tiempo que permiten avanzar en la com-prensión de los mecanismos psicosociales subyacentes.Esta investigación ha sido posible gracias a los Gobiernos de España (PID2020-115738GB-I0; PSI2017- 84145-P; PSI2017-83966-R) y País Vasco (IT1187-19; PRE_2017_1_0405), la Universidad del País Vasco (DOCREC20/23), CONICYT (72180394) y la Universidad Viña del Mar (FIIUVM-EN-1904)