Conflicting Tasks and Moral Hazard: Theory and Experimental Evidence

We study a multi-task principal-agent problem in which tasks can be in direct conflict with each other. In theory, it is difficult to induce a single agent to exert efforts in two conflicting tasks, because effort in one task decreases the success probability of the other task. We have conducted an experiment in which we find strong support for the relevance of this incentive problem. In the presence of conflict, subjects choose two efforts significantly less often when both tasks are assigned to a single agent than when there are two agents each in charge of one task.moral hazard, conflicting tasks, experiment

SDSS J212531.92–010745.9 : the first definite PG 1159 close binary system

Aims. The archival spectrum of SDSS J212531.92−010745.9 shows not only the typical signature of a PG 1159 star, but also indicates the presence of a companion. Our aim was the proof of the binary nature of this object and the determination of its orbital period. Methods. We performed time-series photometry of SDSS J212531.92−010745.9. We observed the object during 10 nights, spread over one month, with the Tübingen 80 cm and the Göttingen 50 cm telescopes. We fitted the observed light curve with a sine and simulated the light curve of this system with the nightfall program. Furthermore, we compared the spectrum of SDSS J212531.92−010745.9 with NLTE models, the results of which also constrain the light curve solution. Results. An orbital period of 6.95616(33) h with an amplitude of 0.354(3) mag is derived from our observations. A pulsation period could not be detected. For the PG 1159 star we found, as preliminary results from comparison with our NLTE models, T eff ∼ 90 000 K, log g ∼ 7.60, and the abundance ratio C/He ∼ 0.05 by number fraction. For the companion we obtained with a mean radius of 0.4 ± 0.1 R, a mass of 0.4 ± 0.1 M, and a temperature of 8200 K on the irradiated side, good agreement between the observed light curve and the nightfall simulation, but we do not regard those values as final

Public-private partnerships versus traditional procurement: An experimental investigation

A government agency wants an infrastructure-based public service to be provided. Our experimental study compares two different modes of provision. In a public-private partnership, the two tasks of building the infrastructure and operating it are delegated to one private contractor (a consortium), while under traditional procurement, these tasks are delegated to separate contractors. We find support for the theoretical prediction that, compared to traditional procurement, a public-private partnership provides stronger incentives to make cost-reducing investments (which may increase or decrease service quality). In two additional treatments, we study governance structures which explicitly take subcontracting within private consortia into account.experiment, incomplete contracts, procurement, public-private partnerships

Circulating calcitonin and carcinoembryonic antigen m-RNA detected by RT-PCR as tumour markers in medullary thyroid carcinoma

Detection of local relapse or metastasis in medullary thyroid carcinoma (MTC) continue to pose a major diagnostic challenge. Besides established diagnostic studies such as serum calcitonin (CT) and carcinoembryonic antigen (CEA), molecular detection of circulating tumour cells may be an additional diagnostic tool for the early detection of disease recurrence. We performed reverse transcription-polymerase chain reaction (RT-PCR) on blood samples from patients diagnosed with MTC disease using primers specific for CT and CEA, respectively. CT mRNA was not detectable in peripheral blood of all patients with MTC (n = 11) and all controls (n = 32). CEA mRNA was significantly more often detected patients with MTC (72.7%) than in controls (34.4%; p = 0.038; Fisher exact test). With an example of a patient with MTC and massive tumour mass in the neck we demonstrate the failure of detection of CT mRNA over a period of 6 months, whereas CEA mRNA could be detected in peripheral blood of this patient. As a consequence, CT mRNA detected by RT-PCR in the peripheral blood can not be recommended as a tumour marker in MTC. However, the use of carcinoembryonic mRNA may provide a significant improvement in diagnosis of recurrent disease in MTC. © 2001 Cancer Research Campaign   http://www.bjcancer.co

Suppression of X-rays during an optical outburst of the helium dwarf nova KL Dra

KL Dra is a helium accreting AM CVn binary system with an orbital period close to 25 mins. Approximately every 60 days there is a 4 mag optical outburst lasting ~10 days. We present the most sensitive X-ray observations made of an AM CVn system during an outburst cycle. A series of eight observations were made using XMM-Newton which started shortly after the onset of an optical outburst. We find that X-rays are suppressed during the optical outburst. There is some evidence for a spectral evolution of the X-ray spectrum during the course of the outburst. A periodic modulation is seen in the UV data at three epochs -- this is a signature of the binary orbital or the super-hump period. The temperature of the X-ray emitting plasma is cooler compared to dwarf novae, which may suggest a wind is the origin of a significant fraction of the X-ray flux.Comment: Accepted by MNRA

Dynamic masses for the close PG1159 binary SDSSJ212531.92-010745.9

SDSSJ212531.92-010745.9 is the first known PG1159 star in a close binary with a late main sequence companion allowing a dynamical mass determination. The system shows flux variations with a peak-to-peak amplitude of about 0.7 mag and a period of about 6.96h. In August 2007, 13 spectra of SDSSJ212531.92-010745.9 covering the full orbital phase range were taken at the TWIN 3.5m telescope at the Calar Alto Observatory (Alm\'{e}ria, Spain). These confirm the typical PG1159 features seen in the SDSS discovery spectrum, together with the Balmer series of hydrogen in emission (plus other emission lines), interpreted as signature of the companion's irradiated side. A radial velocity curve was obtained for both components. Using co-added radial-velocity-corrected spectra, the spectral analysis of the PG1159 star is being refined. The system's lightcurve, obtained during three seasons of photometry with the G\"ottingen 50cm and T\"ubingen 80cm telescopes, was fitted with both the NIGHTFALL and PHOEBE binary simulation programs. An accurate mass determination of the PG1159 component from the radial velocity measurements requires to first derive the inclination, which requires light curve modelling and yields further constraints on radii, effective temperature and separation of the system's components. From the analysis of all data available so far, we present the possible mass range for the PG1159 component of SDSSJ212531.92-010745.9.Comment: 8 pages, in "White dwarfs", proceedings of the 16th European White Dwarf Workshop, eds. E. Garcia-Berro, M. Hernanz, J. Isern, S. Torres, to be published in J. Phys.: Conf. Se

Locality and topology with fat link overlap actions

We study the locality and topological properties of fat link clover overlap (FCO) actions. We find that a small amount of fattening (2-4 steps of APE or 1 step of HYP) already results in greatly improved properties compared to the Wilson overlap (WO). We present a detailed study of the localisation of the FCO and its connection to the density of low modes of $A^\dagger A$. In contrast to the Wilson overlap, on quenched gauge backgrounds we do not find any dependence of the localization of the FCO on the gauge coupling. This suggests that the FCO remains local in the continuum limit. The FCO also faithfully reproduces the zero mode wave functions of typical lattice instantons, not like the Wilson overlap. After a general discussion of different lattice definitions of the topological charge we also show that the FCO together with the Boulder charge are likely to satisfy the index theorem in the continuum limit. Finally, we present a high statistics computation of the quenched topological susceptibility with the FCO action.Comment: 19 pages, LaTe

Molecular detection of thyroglobulin mRNA transcripts in peripheral blood of patients with thyroid disease by RT-PCR

The sensitive detection of circulating tumour cells in patients with differentiated thyroid cancer may precede the detection of relapse by other diagnostic studies – such as serum thyroglobulin – and thus may have important therapeutic and prognostic implications. We performed reverse transcription-polymerase chain reaction (RT-PCR) on blood samples from patients diagnosed with thyroid disease using two different RT-PCR sensitivities. Additionally, tissue specificity of TG mRNA-expression was determined using RNA extracts from 27 different human tissues. The lower limit of detection was 50–100 TG mRNA producing cells/ml blood using a ‘normal’ RT-PCR sensitivity and 10–20 cells/ml blood using a ‘high’ sensitivity. With the normal sensitivity TG mRNA was detected in 9/13 patients with thyroid cancer and metastasis, 63/137 patients with a history of thyroid cancer and no metastasis, 21/85 with non-malignant thyroid disease and 9/50 controls. With the high sensitivity TG mRNA was detected in 11/13 patients with thyroid cancer and metastasis, 111/137 patients with a history of thyroid cancer and no metastasis, 61/85 with non-malignant thyroid disease and 41/50 controls. Interestingly, using the normal RT-PCR sensitivity TG mRNA transcripts are specific for thyroid tissue and detectable in the peripheral blood of controls and patients with thyroid disease, which correlates with a diagnosis of metastasized thyroid cancer. However, with a high RT-PCR sensitivity, TG mRNA expression was found not to be specific for thyroid tissue and was not correlated with a diagnosis of thyroid cancer in patients. As a consequence, to date TG mRNA detected by RT-PCR in the peripheral blood cannot be recommended as a tumour marker superior to TG serum-level. © 2000 Cancer Research Campaig