Security and confidentiality approach for the Clinical E-Science Framework (CLEF)

CLEF is an MRC sponsored project in the E-Science programme that aims to establish policies and infrastructure for the next generation of integrated clinical and bioscience research. One of the major goals of the project is to provide a pseudonymised repository of histories of cancer patients that can be accessed by researchers. Robust mechanisms and policies are needed to ensure that patient privacy and confidentiality are preserved while delivering a repository of such medically rich information for the purposes of scientific research. This paper summarises the overall approach adopted by CLEF to meet data protection requirements, including the data flows and pseudonymisation mechanisms that are currently being developed. Intended constraints and monitoring policies that will apply to research interrogation of the repository are also outlined. Once evaluated, it is hoped that the CLEF approach can serve as a model for other distributed electronic health record repositories to be accessed for research

Security and confidentiality approach for the Clinical E-Science Framework (CLEF)

Objectives: CLEF is an MRC sponsored project in the E-Science programme that aims to establish methodologies and a technical infrastructure for the next generation of integrated clinical and bioscience research. Methods: The heart of the CLEF approach to this challenge is to design and develop a pseudonymised repository of histories of cancer patients that can be accessed by researchers. Robust mechanisms and policies have been developed to ensure that patient privacy and confidentiality are preserved while delivering a repository of such medically rich information for the purposes of scientific research. Results: This paper summarises the overall approach adopted by CLEF to meet data protection requirements, including the data flows, pseudonymisation measures and additional monitoring policies that are currently being developed. Conclusion: Once evaluated, it is hoped that the CLEF approach can serve as a model for other distributed electronic health record repositories to be accessed for research

Hysteroscopic Surgery for Submucosal Fibroids

This chapter presents a contemporary summary of the evidence of the clinical impact of submucosal fibroids and discusses the methods used to investigate and surgically manage this common gynaecological condition

Traditional Wisdom for Sustainable Agri and Livestock Production: An Opportunity for Better Animal, Human and Environment Health

Animal production is poised to make a generous leap in the years to come because of the multiplicity of the related events that are taking place around the globe. Increased demand of the livestock products, ease of market accessibility, and opportunity of global trade, increased cash flow in urban and rural societies, application of science and application of new technologies in production, feeding & processing may be some of the key factors responsible for the anticipated increase in livestock production. However, at the same time it is high time that we address some areas of quality assurance of feed & food of animal origin, maintaining the production in spite of scarcity of land, water and imminent climate change In nutshell it is high time we integrate Animal health and Agriculture sector for better sustainability of farming community y and simultaneously addressing the national food security .Needless to mention, education of rural masses for adopting new techniques will play a significant role in entire process of livelihood generation of farming community. The traditional wisdom of ancient India existed in integration of “5F”, which meant Food, Feed, Fodder, Fuel & Fertilizer security. In the current era, Ayurvet with help of modern science has worked on the above model using technological tools for addressing the needs of Animal, Human & Environment Health

Building data analytics capability to increase information processing capacity: The case of a professional service firm

Supply chain literature has emphasised the importance of data analytics capability in driving supply chain outcomes. Additionally, along with knowledge and professional judgement, providing data-driven analyses has become a critical component of professional service operations. However, there remains little understanding of how organisations build data analytics capability to reduce supply network uncertainty. A single case study of a professional service firm revealed analytics capability to be a combination of three capabilities, each with its distinct micro-foundations. We argue that the development of analytics capability requires the interaction of individual abilities and knowledge-bases with social and technical interorganisational processes and structures

Joining up health and bioinformatics: e-science meets e-health

CLEF (Co-operative Clinical e-Science Framework) is an MRC sponsored project in the e-Science programme that aims to establish methodologies and a technical infrastructure forthe next generation of integrated clinical and bioscience research. It is developing methodsfor managing and using pseudonymised repositories of the long-term patient histories whichcan be linked to genetic, genomic information or used to support patient care. CLEF concentrateson removing key barriers to managing such repositories ? ethical issues, informationcapture, integration of disparate sources into coherent ?chronicles? of events, userorientedmechanisms for querying and displaying the information, and compiling the requiredknowledge resources. This paper describes the overall information flow and technicalapproach designed to meet these aims within a Grid framework

Mechanoluminescnce and photoluminescence in gamma irradiated NaCl:Eu

Rare earth (RE) ions posses unique optical behavior when doped into phosphors. Eu2+ activated phosphors find use in many applications. Eu2+ emission arises from the lowest band of 4f6 5d configuration to 8S7/2  state of 4f7. NaCl having different concentrations of Eu were prepared by melt technique. The crystals of small sizes were cleaved from the grown crystal block and crushed to obtain powder or microcrystalline form of NaCl. Annealed samples were exposed to gamma rays at dose level 0.930kGy. Mechanoluminescnce (ML) was excited impulsively by dropping a load of mass 0.4 kg with the impact velocity of   0.6 ms-1 on to it. An intense ML peak was observed in its ML glow curve. ML intensity increases with increasing concentration of dopant. ML emission spectrum shows a single peak at 482 nm. Photoluminescence (PL) of the sample has also been recorded and a single peak at 427 nm was observed. Shift in ML and PL emission spectrum was observed

Network orchestration in a large inter-organizational project

Multiple organizations working jointly on shared activities in inter-organizational projects for a defined period of time are used increasingly to coordinate the supply of complex products, subsystems, and services across many industries. Despite the growth in inter-organizational networks as an organizational form, scholars have only recently begun to identify how lead organizations orchestrate the coordination of multiple parties with disparate goals, responsibilities, and capabilities. Prior work offers limited insights into the choice of network governance forms, and how coordination is undertaken by the network orchestrator to govern these networks. We conducted a longitudinal study of four networks to deliver vital services into a large project. We identified how the choice of network governance form was based on task complexity. A shared governance form was chosen for networks developed to deliver routine services, whereas a lead organization governance form was chosen for networks set up to deliver complex services. However, findings showed that the selection of an appropriate governance form was not sufficient for ensuring high performance. The network orchestrator's mode of coordination (formal or informal), the intensity of coordination (active or passive), and fit with the form of governance form (shared or lead organization governed) was important in driving performance