26,964 research outputs found
Capital Structure of Public–Private Partnership Projects: A Sustainability Perspective
Capital is key to achieve the standardized operation of public–private partnership (PPP) projects. The capital structure of PPP projects stresses the structure of equity and debt funds, which are important for securing life-cycle ample funds and achieving the expected outcomes of projects. By incorporating sustainability into PPP projects, the capital structure not only secures current needs of funds, it also focuses on life-cycle stable operations and achieves economic, social, and environmental benefits. This study first set the equity–debt ratio and equity investment ratio of the private sector as the dependent variables and built a selection model of the capital structure of PPP projects from a sustainability perspective using the benefit, cost, and project conditions as core factors based on multi-objective programming and a discounted cash-flow model. Then, the qualitative analysis could be achieved according to the analysis of critical factors that had not been calculated. Afterwards, a selection process which combined the multi-objective programming model with qualitative analysis was proposed to achieve a comprehensive selection of the capital structure of PPP projects from the sustainability perspective. Finally, the process was applied to a real project to verify its rationality and usability. This study not only enriches the theoretical research of PPP projects and provides a new idea on which to build the capital structure selection model, it also proposes a selection process that can provide scientific references for the selection and optimization of the capital structure of PPP projects in practice
Aerosol reactor production of uniform submicron powders
A method of producing submicron nonagglomerated particles in a single stage reactor includes introducing a reactant or mixture of reactants at one end while varying the temperature along the reactor to initiate reactions at a low rate. As homogeneously small numbers of seed particles generated in the initial section of the reactor progress through the reactor, the reaction is gradually accelerated through programmed increases in temperature along the length of the reactor to promote particle growth by chemical vapor deposition while minimizing agglomerate formation by maintaining a sufficiently low number concentration of particles in the reactor such that coagulation is inhibited within the residence time of particles in the reactor. The maximum temperature and minimum residence time is defined by a combination of temperature and residence time that is necessary to bring the reaction to completion. In one embodiment, electronic grade silane and high purity nitrogen are introduced into the reactor and temperatures of approximately 770.degree. K. to 1550.degree. K. are employed. In another embodiment silane and ammonia are employed at temperatures from 750.degree. K. to 1800.degree. K
Manipulation of heat current by the interface between graphene and white graphene
We investigate the heat current flowing across the interface between graphene
and hexagonal boron nitride (so-called white graphene) using both molecular
dynamics simulation and nonequilibrium Green's function approaches. These two
distinct methods discover the same phenomena that the heat current is reduced
linearly with increasing interface length, and the zigzag interface causes
stronger reduction of heat current than the armchair interface. These phenomena
are interpreted by both the lattice dynamics analysis and the transmission
function explanation, which both reveal that the localized phonon modes at
interfaces are responsible for the heat management. The room temperature
interface thermal resistance is about mK/W in zigzag
interface and mK/W in armchair interface, which
directly results in stronger heat reduction in zigzag interface. Our
theoretical results provide a specific route for experimentalists to control
the heat transport in the graphene and hexagonal boron nitride compound through
shaping the interface between these two materials.Comment: accepted by EP
Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled.
Frizzled is the earliest discovered glycosylated Wnt protein receptor and is critical for the initiation of Wnt signaling. Antagonizing Frizzled is effective in inhibiting the growth of multiple tumor types. The extracellular N terminus of Frizzled contains a conserved cysteine-rich domain that directly interacts with Wnt ligands. Structure-based virtual screening and cell-based assays were used to identify five small molecules that can inhibit canonical Wnt signaling and have low IC50 values in the micromolar range. NMR experiments confirmed that these compounds specifically bind to the Wnt binding site on the Frizzled8 cysteine-rich domain with submicromolar dissociation constants. Our study confirms the feasibility of targeting the Frizzled cysteine-rich domain as an effective way of regulating canonical Wnt signaling. These small molecules can be further optimized into more potent therapeutic agents for regulating abnormal Wnt signaling by targeting Frizzled
Glueball Spectrum from the B.S. Equation
The mass of the glueballs is calculated in the B.S. equation framework. Under
instantaneous approximation, the wave function of B.S. equations are obtained.
The kernel is chosen as the sum of an one-gluon exchange potential, a contact
interaction and a linear confining potential. The numerical results are in
agreement with that of recent lattice calculation.Comment: TeX file, 14 pages, 1 ps figur
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