Human pulpal response to mineral trioxide aggregate (MTA), bioactive glass and calcium hydroxide: A histologic study

Aim:The aim of this study was histological evaluation of the relative success of white mineral trioxide aggregate (MTA), bioactive glass (BAG), and calcium hydroxide (Ca(OH)2) when used as pulp capping agents in human teeth. Materials and Methods:45 healthy premolars scheduled to be extracted for orthodontic reasons were divided into three groups of 15 teeth in each group. The exposed pulps were capped with MTA, Bioglass or Calcium hydroxide. At the end of two months the teeth were extracted and subjected to histological analysis. The sections were blindly evaluated by an experienced and calibrated pathologist. Results: Statistically significant differences were observed among the groups for histological evaluation. A clear superiority of MTA over the other two materials in terms of all the histological criteria evaluated was observed. Conclusions:MTA was observed to be superior to BAG and Ca(OH)2 in terms of histological analysis. Although results favour the use of MTA, more studies with larger samples and a longer follow-up are suggested

An in vitro study to compare antibacterial efficacy of cinnamon extract, neem extract and sodium hypochlorite as root canal irrigants

Background: E. faecalis is the predominant micro-organism recovered from root canal of the teeth where previous endodontic treatment has failed. Thorough debridement and complete elimination of micro-organisms are objectives of an effective endodontic treatment. For many years, intracanal irrigants have been used as an adjunct to enhance antimicrobial effect of cleaning and shaping in endodontics. Aim: The aim of the study is to compare the antibacterial effectiveness between cinnamon extract as irrigant with neem extract irrigant and sodium hypochlorite against E. fecalis. Methodology: The present study is a randomized controlled in vitro study conducted on 90 extracted permanent single rooted teeth. The teeth were divided into three groups- Group 1 was irrigated with cinnamon extract, Group 2 was irrigated with neem extract irrigant and Group 3 with 3% sodium hypochlorite. The colonies in the reduction of E. feacalis was noted as CFU values per ml. Wilcoxon signed ranked test was used to compare in between the three groups. Mann- Whitney's test was used for inter group comparison between the three groups.&nbsp