In vitro effects of 3-(4-Dimethylamino-naphthelen-1-ylmethylene)-1, 3-hydroindolo-2-one) in combination with epigallocatechin gallate on tumour survival in melanoma cells

https://drive.google.com/file/d/153CuXx-7W9fn6HVyPxCHKaYvP9jyRpH4/view?usp=sharinghttps://drive.google.com/drive/folders/1-GtCEd5yMuwzGYVWRhDjdTsXdPaLseIv?usp=sharinghttps://drive.google.com/drive/folders/1ejsusthQqSKYillyASt9KvY8tEQe86K7?usp=sharin

Perceptions of rewards among volunteer caregivers of people living with AIDS working in faith-based organizations in South Africa: a qualitative study

<p>Abstract</p> <p>Background</p> <p>Volunteer caregivers are a critical source of support for the majority of people living with HIV and AIDS in southern Africa, which has extremely high HIV/AIDS prevalence rates. While studies have shown that volunteer caregiving is associated with negative health and socio-economic outcomes, little is known about the positive experiences of volunteers in the home-based care context in South Africa. The purpose of this study is to explore the perception of rewards among volunteers working in home-based care settings.</p> <p>Methods</p> <p>This study uses a qualitative design. Qualitative interviews were conducted with a purposively selected sample of 55 volunteer caregivers using an interview schedule containing open-ended questions.</p> <p>Results</p> <p>Volunteer caregivers derived intrinsic rewards related to self-growth and personal (emotional and psychological) development on the job; they also derived satisfaction from community members taking a liking for them and expressing a need for their services. Volunteers felt gratified by the improvements in their health behaviours, which were a direct consequence of the experiences of caring for terminally ill patients with AIDS. Extrinsic rewards came from appreciation and recognition shown by patients and community members. Extrinsic rewards also accrued to volunteers when the services they rendered made their patients happy. Perhaps the greatest sources of extrinsic rewards are skills and competencies acquired from training and experience while caring for their patients, and volunteers' ability to make a difference in the community.</p> <p>Conclusions</p> <p>Insights into volunteer caregiver rewards provide opportunities for policy makers and programme managers to develop a model of home-based care that facilitates the accrual of rewards to volunteers alongside volunteers' traditional duties of patient care. Programme managers could employ these insights in recruiting and assisting volunteers to identify and reflect on rewards in the caregiving situation as a means of reducing the burden of care and sustaining volunteer interest in caregiving.</p

Optical potentials for the rare-isotope beam era

We review recent progress and motivate the need for further developments in nuclear optical potentials that are widely used in the theoretical analysis of nucleon elastic scattering and reaction cross sections. In regions of the nuclear chart away from stability, which represent a frontier in nuclear science over the coming decade and which will be probed at new rare-isotope beam facilities worldwide, there is a targeted need to quantify and reduce theoretical reaction model uncertainties, especially with respect to nuclear optical potentials. We first describe the primary physics motivations for an improved description of nuclear reactions involving short-lived isotopes, focusing on its benefits for fundamental science discoveries and applications to medicine, energy, and security. We then outline the various methods in use today to build optical potentials starting from phenomenological, microscopic, and ab initio methods, highlighting in particular the strengths and weaknesses of each approach. We then discuss publicly-available tools and resources facilitating the propagation of recent progresses in the field to practitioners. Finally, we provide a set of open challenges and recommendations for the field to advance the fundamental science goals of nuclear reaction studies in the rare-isotope beam era.Comment: This paper is the outcome of the Facility for Rare Isotope Beams Theory Alliance (FRIB - TA) topical program "Optical Potentials in Nuclear Physics" held in March 2022 at FRIB. Its content is non-exhaustive, was chosen by the participants and reflects their efforts related to optical potential

Language rights, intercultural communication and the law in South Africa

This article seeks to explore the present language scenario in courts of law. The article makes use of section 6 of the Constitution of the Republic of South Africa (1996), as a point of departure. At face value this section seems to entrench the language rights of individuals. This would mean that individuals could request trials to be held in their mother tongues, with fluent and competent speakers of that mother tongue sitting on the bench. However, this has not materialised. Contrary to popular opinion, the article argues that individual language rights are to some extent entrenched in the Constitution, but there are no mechanisms to secure such rights in the public domain. The article argues that it is often only language privileges that are preserved in institutions such as the justice system. Legally speaking, there is an obligation on the State to provide interpreters to facilitate access to all eleven official languages in courts of law. This in itself presents numerous challenges. The article argues further that the corollary to this is that there is very little space for intercultural communication in courts of law (as defined by Ting-Toomey, 1999, and Gibson, 2002). There has been little or no capacity building in this regard. It is English, to some extent Afrikaans, and the western cultural paradigm, which prevails. The result is further communication breakdown and language intolerance. In this article, the notion of language rights in courts of law is explored against the backdrop of existing theories of intercultural communication

An evaluation of the state of wellness amongst medical aid company employees in South Africa

Huidige navorsing op die gebied van welstand in die werkplek is gefragmenteer en vereis ’n holistiese, geïntegreerde en stelselmatige begrip van werknemerwelstand sodat gesondheiden welstandsorg doeltreffend bestuur kan word. Die toenemende las van nie-oordraagbare toestande in Suid-Afrika beklemtoon die noodsaaklikheid van voorkomingstrategieë soos welstandprogramme. Die werkomgewing bied ’n ideale plek, aangesien ’n groot deel van die bevolking geteiken word, insluitende diegene wie se lewenstyl verbeter moet word. Hierdie studie is dus daarop gemik om verskeie gesondheid- en welstandkomponente onder werknemers van ’n mediesefondsmaatskappy te evalueer in ’n poging om risikogebiede te identifiseer wat verdere ingryping vereis. Die deelnemers het bestaan uit 140 werknemers van ’n mediesefondsmaatskappy wat ten minste 40 h per week werk. Hulle is onderwerp aan ’n welstandassesseringsbattery bestaande uit antropometrieke, gesondheidverwante en fisieke kapasiteitmetings. Die resultate toon dat ingryping nodig is betreffende alkohol- en dwelmgebruik, dieetgewoontes, hartgesondheid, liggaamsamestelling, spieruithouvermoë, kardiorespiratoriese uithouvermoë en individuele persepsies van die maatskappy. Dié studie het resultate opgelewer wat die bevindings van baie vorige navorsing op hierdie gebied staaf. Die trefwydte van welstandprogramme op die Suid-Afrikaanse bevolking is egter beperk. Die sukses van welstandprogramme wat fisieke aktiwiteit beklemtoon, is goed gedokumenteer in hoë-inkomstelande, met bewys van die ekonomiese voordele en opbrengs op belegging. Gevolglik word daar aangevoer dat die toepassing van welstandprogramme ’n positiewe uitwerking op die Suid-Afrikaanse werkmag sal hê.Current research in the area of wellness in the workplace is fragmented and requires a holistic, integrated and systemic understanding of employee wellness in order for health and wellness care to be effectively managed. The growing burden of noncommunicable conditions in South Africa highlights the necessity for prevention strategies such as wellness programmes to be implemented. The workplace provides an ideal setting as a large proportion of the population will be targeted, including those who require lifestyle improvement. Therefore this study sought to evaluate various health and wellness components among employees of a medical aid company in an attempt to identify risk areas which require further intervention. Participants were 140 employees of a medical aid company who work a minimum of 40 h per week and who were subjected to a wellness assessment battery, consisting of anthropometrical, health-related and physical capacity measurements. The results indicate that intervention is required in terms of alcohol and drug usage, dietary habits, heart health, body composition, muscular endurance, cardiorespiratory endurance, and individual perceptions towards the company. This study produced results which corroborate the findings of a great deal of previous research in this field. However, the scope for applying wellness programmes to the South African population is limited. The success of wellness programmes which emphasise physical activity has been well documented in high-income countries, with evidence of economic benefits and return on investment. And so it is proposed that implementation of wellness programmes will have a positive effect on the South African workforce.http://www.satnt.ac.zaam201