A global multilayer cloud identification with POLDER/PARASOL

The detection of multilayer cloud situations is important for satellite retrieval algorithms and for many climate related applications. In this paper, we describe an algorithm based on the exploitation of the POLarization and Directionality of the Earth’s Reflectance (POLDER) observations to identify monolayered and multilayered cloudy situations along with a confidence index. Our reference comes from the synergy of the active instruments of the A-Train satellite constellation. The algorithm is based upon a decision tree that uses a metric from information theory and a series of tests on POLDER Level-2 products. We obtain a multilayer flag as the final result of a tree classification which takes discrete values between 0 and 100. Values closest to zero (resp. a hundred) indicate a higher confidence in the monolayer (resp. multilayer) character. This indicator can be used as it is, or with a threshold level that minimizes the risk of misclassification, as a binary index to distinguish between monolayer and multilayer clouds. For almost fully covered and optically thick enough cloud scenes, the risk of misclassification ranges from 29% to 34% over the period 2006–2010 and the average confidences in the estimated monolayer and multilayer characters of the cloud scenes are 74.0% and 58.2% respectively. With the binary distinction, POLDER provides a climatology of the mono/multi-layer cloud character that exhibits some interesting features. Comparisons with the performance of the Moderate-Resolution Imaging Spectroradiometer (MODIS) multilayerflag are given

Building capacity for clinical research in developing countries: the INDOX cancer research network experience

Transnational Organisations increasingly prioritise the need to support local research capacity in low and middle income countries in order that local priorities are addressed with due consideration of contextual issues. There remains limited evidence on the best way in which this should be done or the ways in which external agencies can support this process

The recent decline in mortality from Hodgkin lymphomas in central and eastern Europe

Background: Hodgkin lymphoma (HL) is a largely curable disease and its mortality had steadily declined in western Europe since the late 1960s. Only modest declines were, however, observed in central/eastern Europe. Materials and methods: We updated trends in mortality from HL in various European areas up to 2004 and analyzed patterns in incidence for selected European countries providing national data. Results: In most western European countries, HL mortality continued to steadily decline up to the mid 2000s. More recent reductions were also observed in eastern European countries. Overall, mortality from HL declined from 1.17/100 000 (age-standardized, world population) in 1980-1989 to 1.42/100 000 in 2000-2004 in men from the 15 member states of the European Union (EU) from western and northern Europe. In the EU 10 accession countries of central and eastern Europe, male mortality from HL was 1.42/100 000 in 1980-1984, 1.32 in 1990-1994, and declined to 0.76 in 2000-2004. Similar trends were observed in women. No consistent patterns were found for HL incidence. Conclusions: The present work confirms the persistent declines in HL mortality in western European countries, and shows favorable patterns over more recent calendar years in central/eastern ones, where rates, however, are still at levels observed in western Europe in the early 1990

Determinants of Acceptance of Cervical Cancer Screening in Dar es Salaam, Tanzania.

To describe how demographic characteristics and knowledge of cervical cancer influence screening acceptance among women living in Dar es Salaam, Tanzania. Multistage cluster sampling was carried out in 45 randomly selected streets in Dar es Salaam. Women between the ages of 25-59 who lived in the sampled streets were invited to a cervical cancer screening; 804 women accepted and 313 rejected the invitation. Information on demographic characteristics and knowledge of cervical cancer were obtained through structured questionnaire interviews. Women aged 35-44 and women aged 45-59 had increased ORs of 3.52 and 7.09, respectively, for accepting screening. Increased accepting rates were also found among single women (OR 2.43) and among women who had attended primary or secondary school (ORs of 1.81 and 1.94). Women who had 0-2 children were also more prone to accept screening in comparison with women who had five or more children (OR 3.21). Finally, knowledge of cervical cancer and awareness of the existing screening program were also associated with increased acceptance rates (ORs of 5.90 and 4.20). There are identifiable subgroups where cervical cancer screening can be increased in Dar es Salaam. Special attention should be paid to women of low education and women of high parity. In addition, knowledge and awareness raising campaigns that goes hand in hand with culturally acceptable screening services will likely lead to an increased uptake of cervical cancer screening

Epidemiology of biliary tract cancers: an update

Background: Biliary tract cancer (BTC) is a rare cancer in Europe and North America, characterized by wide geographic variation, with high incidence in some areas of Latin America and Asia. Materials and methods: BTC mortality and incidence have been updated according to recent data, using joinpoint regression analysis. Results: Since the 1980s, decreasing trends in BTC mortality rates (age-standardized, world standard population) were observed in the European Union as a whole, in Australia, Canada, Hong Kong, Israel, New Zealand, and the United States, and high-risk countries such as Japan and Venezuela. Joinpoint regression analysis indicates that decreasing trends were more favorable over recent calendar periods. High-mortality rates are, however, still evident in central and eastern Europe (4-5/100 000 women), Japan (4/100 000 women), and Chile (16.6/100 000 women). Incidence rates identified other high-risk areas in India (8.5/100 000 women), Korea (5.6/100 000 women), and Shanghai, China (5.2/100 000 women). Conclusions: The decreasing BTC mortality trends essentially reflect more widespread and earlier adoption of cholecystectomy in several countries, since gallstones are the major risk factor for BTC. There are, however, high-risk areas, mainly from South America and India, where access to gall-bladder surgery remains inadequat

Mechanical Analysis of WEST divertor support plate

The Tore Supra tokamak is being transformed in an x-point divertor fusion device in the frame of the WEST (W-for tungsten-Environment in Steady-state Tokamak) project, launched in support to the ITER tungsten divertor strategy. The WEST project aims to test W monoblock Plasma Facing Units (PFU) under long plasma discharge (up to 1000s), with thermal loads of the same magnitude as those expected for ITER. Therefore the divertor is a key component of the WEST project, and so is its support structure, which has to handle strong mechanical loads. The WEST upper and lower divertor are made of 12 30° sectors, each one composed of 38 PFU that can be made of tungsten, CuCrZr or graphite. A generic 316L stainless steel 30° conic support plate is used to hold the 38 PFU together, regardless of their material. The PFUs are fixed on the support plate thanks to 152 Xm19 stainless steel fixing elements (4 per PFU), and in each of this fixing element an Aluminium-Nickel-Bronze alloy (Al-Ni-Br) pin is engaged in a slotted hole, in order to allow thermal expansion in the length direction of the PFU. The support plate is fixed on the divertor coil casing thanks to 10 M10 screws. Mechanicals loads which act on the PFUs are transmitted to the support plate through the fixing elements. These loads are due to Vertical Displacement Event (VDE), disruptions and thermal expansion of the PFU. First the different load cases, PFU configurations and scenario are presented. Then an ANSYS plastic mechanical simulation is performed in order to validate the number of cycles of the support plate for each scenario: 30 000 cycles in steady-state and 3000 cycles in VDE. Finally reactions forces from the previous ANSYS simulation are used in order to calculate the stress in the M10 screws

Should colorectal cancer screening start at the same age in European countries? Contributions from descriptive epidemiology

We assessed incidence and mortality of colorectal cancer (CRC) at various ages among women and men in 38 European countries. The ages at which defined levels of incidence and mortality were reached varied between 9 and 17 years between countries. This variation requires consideration in the definition of screening guidelines

Adjustment to colostomy: stoma acceptance, stoma care self-efficacy and interpersonal relationships

‘The definitive version is available at www.blackwell-synergy.com.’ Copyright Blackwell Publishing. DOI: 10.1111/j.1365-2648.2007.04446.xThis paper is a report of a study to examine adjustment and its relationship with stoma acceptance and social interaction, and the link between stoma care self-efficacy and adjustment in the presence of acceptance and social interactions.Peer reviewe