52 research outputs found
Nucleosynthesis: Stellar and Solar Abundances and Atomic Data
Abundance observations indicate the presence of often surprisingly large
amounts of neutron capture (i.e., s- and r-process) elements in old Galactic
halo and globular cluster stars. These observations provide insight into the
nature of the earliest generations of stars in the Galaxy -- the progenitors of
the halo stars -- responsible for neutron-capture synthesis. Comparisons of
abundance trends can be used to understand the chemical evolution of the Galaxy
and the nature of heavy element nucleosynthesis. In addition age
determinations, based upon long-lived radioactive nuclei abundances, can now be
obtained. These stellar abundance determinations depend critically upon atomic
data. Improved laboratory transition probabilities have been recently obtained
for a number of elements. These new gf values have been used to greatly refine
the abundances of neutron-capture elemental abundances in the solar photosphere
and in very metal-poor Galactic halo stars. The newly determined stellar
abundances are surprisingly consistent with a (relative) Solar System r-process
pattern, and are also consistent with abundance predictions expected from such
neutron-capture nucleosynthesis.Comment: 8 pages, 2 figures, 1 table. To appear in the Proceedings of the NASA
Laboratory Astrophysics Workshop in Las Vegas, NV (February 2006
The ESO Nearby Abell Cluster Survey. III. Distribution and Kinematics of Emission-Line Galaxies
We have studied the frequency of occurrence, the kinematics and the spatial
distribution of Emission-Line Galaxies (ELG) in clusters in the ESO Nearby
Abell Cluster Survey (ENACS). More than 90% of the ELG are spirals, but the ELG
represent only 30% of all spirals. The true ELG fraction in clusters is 0.10;
this is consistent with that in the field (0.21) as a result of differences in
morphological mix. The average ELG fraction decreases with increasing velocity
dispersion of the cluster. Only 1/5 of the clusters shows a significant
difference in the average velocities of the ELG and the other (non-ELG)
galaxies; in a similar fraction of the clusters significant differences in
velocity dispersion are seen. Yet, the velocity dispersion of the ELG is, on
average, 20% larger than that of the non-ELG. This larger velocity dispersion
is largely intrinsic, i.e. it is not likely to be the result of velocity
offsets of the ELG. The surface density of the ELG is significantly less peaked
towards the centre than that of the non-ELG. The ELG are distributed fairly
smoothly within the cluster with at most 25% in compact substructures. The
distribution and kinematics of the ELG yield virial mass estimates that, on
average, are 50% higher than those based on the non-ELG. This probably means
that the ELG are on more radial orbits than the non-ELG. All observed
properties of the ELG are consistent with most of them being on their first
approach of the high-density cluster core.Comment: 23 LaTeX pages, 13 figures, to be published in A&A; uuencoded
compressed ps file also available at ftp://132.229.8.14
Study of the Dependency on Magnetic Field and Bias Voltage of an AC-Biased TES Microcalorimeter
At SRON we are studying the performance of a Goddard Space Flight Center single pixel TES microcalorimeter operated in an AC bias configuration. For x-ray photons at 6 keV the pixel shows an x-ray energy resolution Delta E(sub FWHM) = 3.7 eV, which is about a factor 2 worse than the energy resolution observed in an identical DC-biased pixel. In order to better understand the reasons for this discrepancy we characterized the detector as a function of temperature, bias working point and applied perpendicular magnetic field. A strong periodic dependency of the detector noise on the TES AC bias voltage is measured. We discuss the results in the framework of the recently observed weak-link behaviour of a TES microcalorimeter
ORIGIN: Metal Creation and Evolution from the Cosmic Dawn
ORIGIN is a proposal for the M3 mission call of ESA aimed at the study of metal creation from the epoch of cosmic dawn. Using high-spectral resolution in the soft X-ray band, ORIGIN will be able to identify the physical conditions of all abundant elements between C and Ni to red-shifts of z=10, and beyond. The mission will answer questions such as: When were the first metals created? How does the cosmic metal content evolve? Where do most of the metals reside in the Universe? What is the role of metals in structure formation and evolution? To reach out to the early Universe ORIGIN will use Gamma-Ray Bursts (GRBs) to study their local environments in their host galaxies. This requires the capability to slew the satellite in less than a minute to the GRB location. By studying the chemical composition and properties of clusters of galaxies we can extend the range of exploration to lower redshifts (z approx. 0.2). For this task we need a high-resolution spectral imaging instrument with a large field of view. Using the same instrument, we can also study the so far only partially detected baryons in the Warm-Hot Intergalactic Medium (WHIM). The less dense part of the WHIM will be studied using absorption lines at low redshift in the spectra for GRBs. The ORIGIN mission includes a Transient Event Detector (coded mask with a sensitivity of 0.4 photon/sq cm/s in 10 s in the 5-150 keV band) to identify and localize 2000 GRBs over a five year mission, of which approx.65 GRBs have a redshift >7. The Cryogenic Imaging Spectrometer, with a spectral resolution of 2.5 eV, a field of view of 30 arcmin and large effective area below 1 keV has the sensitivity to study clusters up to a significant fraction of the virial radius and to map the denser parts of the WHIM (factor 30 higher than achievable with current instruments). The payload is complemented by a Burst InfraRed Telescope to enable onboard red-shift determination of GRBs (hence securing proper follow up of high-z bursts) and also probes the mildly ionized state of the gas. Fast repointing is achieved by a dedicated Controlled Momentum Gyro and a low background is achieved by the selected low Earth orbit
Reduced costs with bisoprolol treatment for heart failure - An economic analysis of the second Cardiac Insufficiency Bisoprolol Study (CIBIS-II)
Background
Beta-blockers, used as an adjunctive to diuretics, digoxin and angiotensin converting enzyme inhibitors, improve survival in chronic heart failure. We report a prospectively planned economic analysis of the cost of adjunctive beta-blocker therapy in the second Cardiac Insufficiency BIsoprolol Study (CIBIS II).
Methods
Resource utilization data (drug therapy, number of hospital admissions, length of hospital stay, ward type) were collected prospectively in all patients in CIBIS . These data were used to determine the additional direct costs incurred, and savings made, with bisoprolol therapy. As well as the cost of the drug, additional costs related to bisoprolol therapy were added to cover the supervision of treatment initiation and titration (four outpatient clinic/office visits). Per them (hospital bed day) costings were carried out for France, Germany and the U.K. Diagnosis related group costings were performed for France and the U.K. Our analyses took the perspective of a third party payer in France and Germany and the National Health Service in the U.K.
Results
Overall, fewer patients were hospitalized in the bisoprolol group, there were fewer hospital admissions perpatient hospitalized, fewer hospital admissions overall, fewer days spent in hospital and fewer days spent in the most expensive type of ward. As a consequence the cost of care in the bisoprolol group was 5-10% less in all three countries, in the per them analysis, even taking into account the cost of bisoprolol and the extra initiation/up-titration visits. The cost per patient treated in the placebo and bisoprolol groups was FF35 009 vs FF31 762 in France, DM11 563 vs DM10 784 in Germany and pound 4987 vs pound 4722 in the U.K. The diagnosis related group analysis gave similar results.
Interpretation
Not only did bisoprolol increase survival and reduce hospital admissions in CIBIS II, it also cut the cost of care in so doing. This `win-win' situation of positive health benefits associated with cost savings is Favourable from the point of view of both the patient and health care systems. These findings add further support for the use of beta-blockers in chronic heart failure
- …