14,250 research outputs found
Large transverse field tunnel splittings in the Fe_8 spin Hamiltonian
The spin Hamiltonian that describes the molecular magnet Fe has biaxial
symmetry with mutually perpendicular easy, medium, and hard magnetic axes.
Previous calculations of the ground state tunnel splittings in the presence of
a magnetic field along the hard axis are extended, and the meaning of the
previously discovered oscillation of this splitting is further clarified
Oscillatory Tunnel Splittings in Spin Systems: A Discrete Wentzel-Kramers-Brillouin Approach
Certain spin Hamiltonians that give rise to tunnel splittings that are viewed
in terms of interfering instanton trajectories, are restudied using a discrete
WKB method, that is more elementary, and also yields wavefunctions and
preexponential factors for the splittings. A novel turning point inside the
classically forbidden region is analysed, and a general formula is obtained for
the splittings. The result is appled to the \Fe8 system. A previous result for
the oscillation of the ground state splitting with external magnetic field is
extended to higher levels.Comment: RevTex, one ps figur
Quenched Spin Tunneling and Diabolical Points in Magnetic Molecules: II. Asymmetric Configurations
The perfect quenching of spin tunneling first predicted for a model with
biaxial symmetry, and recently observed in the magnetic molecule Fe_8, is
further studied using the discrete phase integral (or
Wentzel-Kramers-Brillouin) method. The analysis of the previous paper is
extended to the case where the magnetic field has both hard and easy
components, so that the Hamiltonian has no obvious symmetry. Herring's formula
is now inapplicable, so the problem is solved by finding the wavefunction and
using connection formulas at every turning point. A general formula for the
energy surface in the vicinity of the diabolo is obtained in this way. This
formula gives the tunneling apmplitude between two wells unrelated by symmetry
in terms of a small number of action integrals, and appears to be generally
valid, even for problems where the recursion contains more than five terms.
Explicit results are obtained for the diabolical points in the model for Fe_8.
These results exactly parallel the experimental observations. It is found that
the leading semiclassical results for the diabolical points appear to be exact,
and the points themselves lie on a perfect centered rectangular lattice in the
magnetic field space. A variety of evidence in favor of this perfect lattice
hypothesis is presented.Comment: Revtex; 4 ps figures; follow up to cond-mat/000311
Spin Tunneling in Magnetic Molecules: Quasisingular Perturbations and Discontinuous SU(2) Instantons
Spin coherent state path integrals with discontinuous semiclassical paths are
investigated with special reference to a realistic model for the magnetic
degrees of freedom in the Fe8 molecular solid. It is shown that such paths are
essential to a proper understanding of the phenomenon of quenched spin
tunneling in these molecules. In the Fe8 problem, such paths are shown to arise
as soon as a fourth order anisotropy term in the energy is turned on, making
this term a singular perturbation from the semiclassical point of view. The
instanton approximation is shown to quantitatively explain the magnetic field
dependence of the tunnel splitting, as well as agree with general rules for the
number of quenching points allowed for a given value of spin. An accurate
approximate formula for the spacing between quenching points is derived
Corticosteroid implants for chronic non-infectious uveitis.
BACKGROUND: Uveitis is a term used to describe a heterogeneous group of intraocular inflammatory diseases of the anterior, intermediate, and posterior uveal tract (iris, ciliary body, choroid). Uveitis is the fifth most common cause of vision loss in high-income countries, accounting for 5% to 20% of legal blindness, with the highest incidence of disease in the working-age population.Corticosteroids are the mainstay of acute treatment for all anatomical subtypes of non-infectious uveitis and can be administered orally, topically with drops or ointments, by periocular (around the eye) or intravitreal (inside the eye) injection, or by surgical implantation.
OBJECTIVES: To determine the efficacy and safety of steroid implants in people with chronic non-infectious posterior uveitis, intermediate uveitis, and panuveitis.
SEARCH METHODS: We searched CENTRAL (which contains the Cochrane Eyes and Vision Trials Register) (Issue 10, 2015), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to November 2015), EMBASE (January 1980 to November 2015), PubMed (1948 to November 2015), Latin American and Caribbean Health Sciences Literature Database (LILACS) (1982 to November 2015), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com) (last searched 15 April 2013), ClinicalTrials.gov (www.clinicaltrials.gov), and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic search for studies. We last searched the electronic databases on 6 November 2015.We also searched reference lists of included study reports, citation databases, and abstracts and clinical study presentations from professional meetings.
SELECTION CRITERIA: We included randomized controlled trials comparing either fluocinolone acetonide (FA) or dexamethasone intravitreal implants with standard-of-care therapy with at least six months of follow-up after treatment. We included studies that enrolled participants of all ages who had chronic non-infectious posterior uveitis, intermediate uveitis, or panuveitis with vision that was better than hand-motion.
DATA COLLECTION AND ANALYSIS: Two review authors independently reviewed studies for inclusion. Two review authors independently extracted data and assessed the risk of bias for each study.
MAIN RESULTS: We included data from two studies (619 eyes of 401 participants) that compared FA implants with standard-of-care therapy. Both studies used similar standard-of-care therapy that included administration of prednisolone and, if needed, immunosuppressive agents. The studies included participants from Australia, France, Germany, Israel, Italy, Portugal, Saudi Arabia, Spain, Switzerland, Turkey, the United Kingdom, and the United States. We assessed both studies at high risk of performance and detection bias.Only one study reported our primary outcome, recurrence of uveitis at any point during the study through 24 months. The evidence, judged as moderate-quality, showed that a FA implant probably prevents recurrence of uveitis compared with standard-of-care therapy (risk ratio (RR) 0.29, 95% confidence interval (CI) 0.14 to 0.59; 132 eyes). Both studies reported safety outcomes, and moderate-quality evidence showed increased risks of needing cataract surgery (RR 2.98, 95% CI 2.33 to 3.79; 371 eyes) and surgery to lower intraocular pressure (RR 7.48, 95% CI 3.94 to 14.19; 599 eyes) in the implant group compared with standard-of-care therapy through two years of follow-up. No studies compared dexamethasone implants with standard-of-care therapy.
AUTHORS\u27 CONCLUSIONS: After considering both benefits and harms reported from two studies in which corticosteroids implants were compared with standard-of-care therapy, we are unable to conclude that the implants are superior to traditional systemic therapy for the treatment of non-infectious uveitis. These studies exhibited heterogeneity in design and outcomes that measured efficacy. Pooled findings regarding safety outcomes suggest increased risks of post-implant surgery for cataract and high intraocular pressure compared with standard-of-care therapy
Bohr-Sommerfeld quantization of spin Hamiltonians
The Bohr-Sommerfeld rule for a spin system is obtained, including the first
quantum corrections. The rule applies to both integer and half-integer spin,
and respects Kramers degeneracy for time-reversal invariant systems. It is
tested for various models, in particular the Lipkin-Meshkov-Glick model, and
found to agree very well with exact results.Comment: Revtex 4, no figures, 1 tabl
Drawing Trees with Perfect Angular Resolution and Polynomial Area
We study methods for drawing trees with perfect angular resolution, i.e.,
with angles at each node v equal to 2{\pi}/d(v). We show:
1. Any unordered tree has a crossing-free straight-line drawing with perfect
angular resolution and polynomial area.
2. There are ordered trees that require exponential area for any
crossing-free straight-line drawing having perfect angular resolution.
3. Any ordered tree has a crossing-free Lombardi-style drawing (where each
edge is represented by a circular arc) with perfect angular resolution and
polynomial area. Thus, our results explore what is achievable with
straight-line drawings and what more is achievable with Lombardi-style
drawings, with respect to drawings of trees with perfect angular resolution.Comment: 30 pages, 17 figure
Macroscopic Quantum Tunneling of a Domain Wall in a Ferromagnetic Metal
The macroscopic quantum tunneling of a planar domain wall in a ferromagnetic
metal is studied based on the Hubbard model. It is found that the ohmic
dissipation is present even at zero temperature due to the gapless Stoner
excitation, which is the crucial difference from the case of the insulating
magnet. The dissipative effect is calculated as a function of width of the wall
and is shown to be effective in a thin wall and in a weak ferromagnet. The
results are discussed in the light of recent experiments on ferromagnets with
strong anisotropy. PACS numbers:75.60.Ch, 03.65.Sq, 75.10.LpComment: 13page
Macroscopic Quantum Tunneling and Dissipation of Domain Wall in Ferromagnetic Metals
The depinning of a domain wall in ferromagentic metal via macroscopic quantum
tunneling is studied based on the Hubbard model. The dynamics of the
magnetization verctor is shown to be governed by an effective action of
Heisenberg model with a term non-local in time that describes the dissipation
due to the conduction electron. Due to the existence of the Fermi surface there
exists Ohmic dissipation even at zero temperature, which is crucially different
from the case of the insulator. Taking into account the effect of pinning and
the external magnetic field the action is rewritten in terms of a collective
coordinate, the position of the wall, . The tunneling rate for is
calculated by use of the instanton method. It is found that the reduction of
the tunneling rate due to the dissipation is very large for a thin domain wall
with thickness of a few times the lattice spacing, but is negligible for a
thick domain wall. Dissipation due to eddy current is shown to be negligible
for a wall of mesoscopic size.Comment: of pages 26, to appear in "Quantum Tunneling of Magnetization, ed. B.
Barbara and L. Gunther (Kluwer Academic Pub.), Figures available by FAX
(81-48-462-4649
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