893 research outputs found

    Доповнення до Списку дійсних членів УМТ

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    Grondwater is wereldwijd de grootste bron van zoet water, en in Nederland hebben we er relatief veel van. Dat heeft te maken met de unieke ligging in een deltagebied waarin dikke pakketten goed doorlatende afzettingen zoals fluviatiele zanden zijn afgezet, met een aanzienlijk neerslagoverschot en met de aanvoer van zoet rivierwater dat deels weer infiltreert. Toch is het ook in Nederland zaak om met het grondwater zorgvuldig om te springen

    The effect of functional roles on group efficiency

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    The usefulness of ‘roles’ as a pedagogical approach to support small group performance can be often read, however, their effect is rarely empirically assessed. Roles promote cohesion and responsibility and decrease so-called ‘process losses’ caused by coordination demands. In addition, roles can increase awareness of intra-group interaction. In this article, the effect of functional roles on group performance, efficiency and collaboration during computer-supported collaborative learning (CSCL) was investigated with questionnaires and quantitative content analysis of e-mail communication. A comparison of thirty-three questionnaire observations, distributed over ten groups in two research conditions: role (n = 5, N = 14) and non-role (n = 5, N = 19), revealed no main effect for performance (grade). A latent variable was interpreted as ‘perceived group efficiency’ (PGE). Multilevel modelling (MLM) yielded a positive marginal effect of PGE. Groups in the role condition appear to be more aware of their efficiency, compared to groups in the ‘non-role’ condition, regardless whether the group performs well or poor. Content analysis reveals that students in the role condition contribute more ‘task content’ focussed statements. This is, however, not as hypothesised due to the premise that roles decrease coordination and thus increase content focused statements; in fact, roles appear to stimulate coordination and simultaneously the amount of ‘task content’ focussed statements increases

    Paracetamol Toxicity: Influence Of Ageing, Frailty, Resveratrol And Sirt1

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    The objective of this thesis was to help improve the safety of paracetamol for patients of all ages by adding evidence to the body of knowledge on the changing risks of paracetamol toxicity in ageing, frailty and non-acute exposures, and the potential for lifespan and healthspan increasing interventions to provide novel mechanisms of paracetamol hepatotoxicity protection. Furthermore, this thesis aimed to investigate the potential of both paracetamol, and lifespan and healthspan interventions in delaying or preventing frailty. Overall the work presented in this thesis used a series of mouse models to contribute to three main findings with clinical significance. Firstly, they demonstrated that there is no increase in susceptibility to paracetamol toxicity in old age or frailty, with either acute, chronic or sub-acute paracetamol exposure. Secondly, they showed that the currently used paracetamol hepatotoxicity therapy, NAC, does not protect against toxicity induced by sub-acute paracetamol exposure. Further studies showed that the mechanism of SIRT1 activation does not provide an alternative protective mechanism. Finally, this thesis found that the lifespan and healthspan increasing interventions of resveratrol and calorie restriction, but not therapeutic paracetamol, were able to delay frailty in aged mice

    A Schema Therapy Based Milieu in Secure Residential Youth Care:Effects on Aggression, Group Climate, Repressive Staff Interventions, and Team Functioning

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    Group care workers of residential youth care settings face the challenge of creating a warm and involved treatment climate against the demands and restrictions of the treatment setting. We tested the effects of SafePath, a milieu-based intervention based on Schema Therapy principles, during the first year of implementation on two secure residential treatment units compared to two control units. Staff’s daily reports on 139 individual patients were coded on use of schema mode language (implementation check), occurrences of aggression (primary outcome) and repressive staff interventions. In addition, repeated questionnaires were filled out by patients (n = 87) on group climate and by staff (n = 50) on team functioning. Compared to the control units, SafePath units showed higher improvements in group climate and repressive interventions. Both SafePath and control units showed decreased aggression over time. Team functioning was consistently better in the SafePath units compared to the care-as-usual units from baseline through 12 months. In conclusion, a Schema Therapy based milieu as implemented with SafePath may contribute to a warm and supportive group climate with less repressive interventions in secure residential youth care

    Observation of coherent transients in ultrashort chirped excitation of an undamped two-level system

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    The effects of Coherent excitation of a two level system with a linearly chirped pulse are studied theoretically and experimentally (in Rb (5s - 5p)) in the low field regime. The Coherent Transients are measured directly on the excited state population on an ultrashort time scale. A sharp step corresponds to the passage through resonance. It is followed by oscillations resulting from interferences between off-resonant and resonant contributions. We finally show the equivalence between this experiment and Fresnel diffraction by a sharp edge.Comment: 4 pages, 4 figures, to appear in PR
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