168 research outputs found

    Turbulence Measurements in Shear Flow Liquid Systems

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    The paper is a composite of a number of years of work on turbulence measurements in a variety of liquid flow systems. The trials and tribulations of such measurements are emphasized. Pipe flow Is considered in some detail, and the consistency between results of various investigators is analyzed. Other systems discussed are a stirred tank unit and a multi-jet reactor configuration. Statistical turbulence measurements such as autocorrelation, spectrum, probability density, flatness factor, and skewness factor are considered in terms of obtaining these from digital signals obtained by conversion of the normal analog signals. Descriptive parameters of statistical turbulence, such as microscale, macroscale, and kinetic energy dissipation, are discussed, as well as various attempts at the estimation of these without using statistical turbulence measurements

    Defining and measuring gender: A social determinant of health whose time has come

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    This paper contributes to a nascent scholarly discussion of sex and gender as determinants of health. Health is a composite of biological makeup and socioeconomic circumstances. Differences in health and illness patterns of men and women are attributable both to sex, or biology, and to gender, that is, social factors such as powerlessness, access to resources, and constrained roles. Using examples such as the greater life expectancy of women in most of the world, despite their relative social disadvantage, and the disproportionate risk of myocardial infarction amongst men, but death from MI amongst women, the independent and combined associations of sex and gender on health are explored. A model for incorporating gender into epidemiologic analyses is proposed

    Early versus Delayed Decompression for Traumatic Cervical Spinal Cord Injury: Results of the Surgical Timing in Acute Spinal Cord Injury Study (STASCIS)

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    BACKGROUND:There is convincing preclinical evidence that early decompression in the setting of spinal cord injury (SCI) improves neurologic outcomes. However, the effect of early surgical decompression in patients with acute SCI remains uncertain. Our objective was to evaluate the relative effectiveness of early (<24 hours after injury) versus late (≥ 24 hours after injury) decompressive surgery after traumatic cervical SCI. METHODS:We performed a multicenter, international, prospective cohort study (Surgical Timing In Acute Spinal Cord Injury Study: STASCIS) in adults aged 16-80 with cervical SCI. Enrolment occurred between 2002 and 2009 at 6 North American centers. The primary outcome was ordinal change in ASIA Impairment Scale (AIS) grade at 6 months follow-up. Secondary outcomes included assessments of complications rates and mortality. FINDINGS:A total of 313 patients with acute cervical SCI were enrolled. Of these, 182 underwent early surgery, at a mean of 14.2(± 5.4) hours, with the remaining 131 having late surgery, at a mean of 48.3(± 29.3) hours. Of the 222 patients with follow-up available at 6 months post injury, 19.8% of patients undergoing early surgery showed a ≥ 2 grade improvement in AIS compared to 8.8% in the late decompression group (OR = 2.57, 95% CI:1.11,5.97). In the multivariate analysis, adjusted for preoperative neurological status and steroid administration, the odds of at least a 2 grade AIS improvement were 2.8 times higher amongst those who underwent early surgery as compared to those who underwent late surgery (OR = 2.83, 95% CI:1.10,7.28). During the 30 day post injury period, there was 1 mortality in both of the surgical groups. Complications occurred in 24.2% of early surgery patients and 30.5% of late surgery patients (p = 0.21). CONCLUSION:Decompression prior to 24 hours after SCI can be performed safely and is associated with improved neurologic outcome, defined as at least a 2 grade AIS improvement at 6 months follow-up

    Christopher Hitchens' Public dying: Toward a Secular-Humanist Ars Moriendi?

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    This article explores the public dying of journalist, writer, provocateur, public intellectual, and renowned atheist, Christopher Hitchens. It does so primarily through an analysis of television interviews given by Hitchens following his diagnosis with esophageal cancer in June 2010. Four key themes are identified as emerging from analysis of the interviews: (a) Hitchens’ explicit sense of mission in challenging myths and superstitions surrounding cancer, dying, and death; (b) the personal experience of terminal illness and dying and the particular way (or style of dying) by which it is approached; (c) issues of regret and a life well lived; and (d) questions surrounding religion, the afterlife, and possibility of deathbed conversion. In light of the claim that ours is a culture in search of an ars moriendi, the article examines what we can learn from Hitchens’ auto/pathographic interviews (and writings) and the extent to which this rational-humanist, atheistic, and stoical style of dying provides a useable “template” for others nearing the end of life

    Rethinking the Architecture: An Action Researcher's Resolution to Writing and Presenting Their Thesis

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    The thesis as a bulky ‘tome’ with a traditional structure - literature review, methodology, research design, findings and conclusions - is a concept under increasing challenge. Recently, I completed a doctoral action research project based on environmental education in a primary school. However, I found that trying to force the action research process into a linear writing structure was an unsatisfactory experience. After much anxiety and considerable experimentation, I resolved the problem of ‘fit’ between action research and the traditional thesis format by creating an alternative architecture based on each of the action research cycles. While still producing a bulky ‘doorstopper’, I feel this structure is a better reflection of the way the study evolved. This paper outlines this new architecture and discusses its rationale. It also challenges other action researchers to innovate and experiment with the ways they represent their research work. License for such innovation is rapidly developing especially with the advent of digital thesis production and performative theses. I see no reason why action researchers cannot be leaders in the creation of new forms of practice about how research theses and dissertations are represented in the academy

    Sweat iodide excretion in patients with cystic fibrosis of the pancreas

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