1,049 research outputs found
Incremental UML for Agile development: embedding UML class models in source code
Agile methods favor "working software over comprehensive documentation." The latter presumably includes Unified Modeling Language. UML is expensive to maintain, and it lacks good drill-down mechanisms, however, UML affords very useful visualizations. This paper describes a discipline for incrementally embedding graphical UML class models within source code for continuous agile development. The approach consists of identifying a main function, and having it drive the piece-wise creation of UML by explicitly including in its postconditions the placement of functions corresponding directly to requirements. The approach thus introduces higher order pre-and postconditions. A specific process is provided for carrying this out, together with examples. It enables UML class model visualization in rapid development, especially when tool-supported
Synergism of Ampicillin and Gentamicin against Obstructive Pyelonephritis Due to Escherichia coli in Rats
(Re)conceptualising physical activity participation as career
Physical activity is increasingly positioned as playing an important role in preventing and mitigating many of the decrements associated with biological ageing. As a result, public health messages encourage older people to remain active in later life. Despite this, physical activity participation rates among older adults are low. This may be in part related to the conventional approach to understanding physical activity participation as a product of motivation. We contend that this approach does not allow for a deeper exploration of the wider structural, historical and discursive contexts in which physical activity participation occurs. Therefore, we propose that physical activity can be reconceptualised as a career. Through a synthesis of findings from four studies exploring physical activity experiences in later life, we demonstrate that beginning and maintaining a physical activity career requires a disposition towards physical activity, the legitimation of physically active practices and dealing with contingencies. In addition, we demonstrate that maintaining a physical activity career requires investment and deliberation to adapt physical activity practices continually within an individual's own personal biography. As such, we conclude that current strategies to promote physical activity to older adults are unlikely to result in increased levels of participation. To promote physical activity to older adults an understanding of how structural, cultural and historical contexts influence participation is needed
Comprehensive geriatric assessment in perioperative care: a protocol for a systematic review and qualitative synthesis
INTRODUCTION: Comprehensive geriatric assessment (CGA) is an intervention that has been deployed in the perioperative setting with the aim to improve outcomes for older patients admitted to hospital. Older patients undergoing surgery are more likely to have postoperative complications, a longer hospital stay and be discharged to a care facility. Despite the increasing application of this intervention within surgical services, the evidence for CGA remains limited in this group. The aim of this systematic review is to describe CGA as in intervention applied to surgical populations in randomised controlled trials (RCTs) as well as the outcomes assessed. METHODS AND ANALYSIS: A systematic search of RCTs of CGA in surgery will be run in Embase, Medline, CINAHL (Cumulative Index to Nursing and Allied Health Literature) and Cochrane library. Further articles will be identified from reference lists in relevant studies found in the search. A narrative synthesis will be undertaken outlining specialties included, detailed descriptions of the intervention and outcomes. ETHICS AND DISSEMINATION: No ethical approval is required. The results of this review will be published and used as the basis of work to optimise this intervention for future trials in surgical populations. PROSPERO REGISTRATION NUMBER: This review is registered with PROSPERO CRD42020221797
Amputation and advance care plans:an observational study exploring decision-making and long-term outcomes in a vascular centre
RC J1148+0455 identification: gravitational lens or group of galaxies ?
The structure of the radio source RC B1146+052 of the ``Cold'' catalogue is
investigated by data of the MIT-GB-VLA survey at 4850 MHz. This source belongs
to the steep spectrum radio sources subsample of the RC catalogue. Its spectral
index is = -1.04. The optical image of this source obtained with 6m
telescope is analysed. The radio source center is situated in a group of 8
galaxies of about 24 in the R-filter. The possible explanations of the
complex structure of radio components are considered.Comment: 6 pages, 5 figures, uses psfig.sty. This was the poster as presented
on Gamow Memorial Internat. Conference GMIC'99 "Early Universe: Cosmological
Problems and Instrumental Technologies" in St.Petersburg, 23-27 Aug., 1999.
Submitted to Proceedings to be published in A&A Transaction
Resumption of elective colorectal surgery during COVID-19 and risk of death
Peer reviewedPostprin
Prevention of Pyelonephritis Due to Escherichia coli in Rats with Gentamicin Stored in Kidney Tissue
Although gentamicin is known to accumulate and persist in the kidneys after sys-temic administration, its antibacterial activity at this site has not been determined. In the present study the accumulation of gentamicin in rat kidneys before infection prevented obstructive pyelonephritis due to Escherichia coli despite heavy urinary tract infection in the obstructed pelvis; thus the kidneys were protected against in-fection in the absence of effective levels of gentamicin in the urine. Stored gentamicin also protected pyelonephritic rats from relapse after complete obstruction of the kidneys. The level of antimicrobial activity of gentamicin in whole kidney tissue was 95 % less than that anticipated on the basis of levels measured after dilution of kidney tissue homogenates; this low level of activity apparently was due in part to high concentrations of solutes. In view of these results in rats, the possibility must be considered that despite reduced activity, gentamicin storage might be useful in the prophylaxis of kidney infection in patients with abnormalities of the urinary tract. In the treatment of established kidney infection, the dose of gentamicin could be reduced and the interval of its administration increased for minimal toxicity
Vortex shear effects in layered superconductors
Motivated by recent transport and magnetization measurements in BSCCO samples
[B. Khaykovich et. al., Phys. Rev. B 61, R9261 (2000)], we present a simple
macroscopic model describing effects of inhomogeneous current distribution and
shear in a layered superconductor. Parameters of the model are deduced from a
microscopic calculation. Our model accounts for the strong current
non-linearities and the re-entrant temperature dependence observed in the
experiment.Comment: 11 pages, 7 figures, submitted to Phys. Rev.
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