4 research outputs found
RNA-binding proteins in bacteria.
RNA-binding proteins (RBPs) are central to most if not all cellular processes,
dictating the fate of virtually all RNA molecules in the cell. Starting with
pioneering work on ribosomal proteins, studies of bacterial RBPs have paved the
way for molecular studies of RNA-protein interactions. Work over the years has
identified major RBPs that act on cellular transcripts at the various stages of
bacterial gene expression and that enable their integration into
post-transcriptional networks that also comprise small non-coding RNAs. Bacterial
RBP research has now entered a new era in which RNA sequencing-based methods
permit mapping of RBP activity in a truly global manner in vivo. Moreover, the
soaring interest in understudied members of host-associated microbiota and
environmental communities is likely to unveil new RBPs and to greatly expand our
knowledge of RNA-protein interactions in bacteria