Spin correlations among the charge carriers in an ordered stripe phase

We have observed a diffuse component to the low-energy magnetic excitation spectrum of stripe-ordered La5/3Sr1/3NiO4 probed by neutron inelastic scattering. The diffuse scattering forms a square pattern with sides parallel and perpendicular to the stripe directions. The signal is dispersive, with a maximum energy of ~10 meV. Probed at 2 meV the scattering decreases in strength with increasing temperature, and is barely visible at 100 K. We argue that the signal originates from dynamic, quasi- one-dimensional, antiferromagnetic correlations among the stripe electrons.Comment: 4 pages, 4 figures. To be published in Physical Review Letter

Visualization of respiratory flows from 3D reconstructed alveolar airspaces using X-ray tomographic microscopy

A deeper knowledge of the three-dimensional (3D) structure of the pulmonary acinus has direct applications in studies on acinar fluid dynamics and aerosol kinematics. To date, however, acinar flow simulations have been often based on geometrical models inspired by morphometrical studies; limitations in the spatial resolution of lung imaging techniques have prevented the simulation of acinar flows using 3D reconstructions of such small structures. In the present study, we use high-resolution, synchrotron radiation-based X-ray tomographic microscopy (SRXTM) images of the pulmonary acinus of a mouse to reconstruct 3D alveolar airspaces and conduct computational fluid dynamic (CFD) simulations mimicking rhythmic breathing motion. Respiratory airflows and Lagrangian (massless) particle tracking are visualized in two examples of acinar geometries with varying size and complexity, representative of terminal sacculi including their alveoli. The present CFD simulations open the path towards future acinar flow and aerosol deposition studies in complete and anatomically realistic multi-generation acinar trees using reconstructed 3D SRXTM geometries

CD14 Deficiency Impacts Glucose Homeostasis in Mice through Altered Adrenal Tone

The toll-like receptors comprise one of the most conserved components of the innate immune system, signaling the presence of molecules of microbial origin. It has been proposed that signaling through TLR4, which requires CD14 to recognize bacterial lipopolysaccharide (LPS), may generate low-grade inflammation and thereby affect insulin sensitivity and glucose metabolism. To examine the long-term influence of partial innate immune signaling disruption on glucose homeostasis, we analyzed knockout mice deficient in CD14 backcrossed into the diabetes-prone C57BL6 background at 6 or 12 months of age. CD14-ko mice, fed either normal or high-fat diets, displayed significant glucose intolerance compared to wild type controls. They also displayed elevated norepinephrine urinary excretion and increased adrenal medullary volume, as well as an enhanced norepinephrine secretory response to insulin-induced hypoglycemia. These results point out a previously unappreciated crosstalk between innate immune- and sympathoadrenal- systems, which exerts a major long-term effect on glucose homeostasis

Chlorpromazine-induced vanishing bile duct syndrome leading to biliary cirrhosis

We describe a 33-yr-old pregnant woman in whom a primary biliary cirrhosis-like syndrome developed after 2 wk of chlorpromazine therapy. The clinical course was characterized by severe jaundice lasting 22 mo, intense pruritus, fever, steatorrhea, high alkaline phosphatase levels and hypercholesterolemia. Jaundice resolved with initiation of ursodeoxycholic acid therapy, but subclinical cholestasis and low-level inflammatory activity persisted and ultimately evolved into biliary cirrhosis. The pathological substrate of this severe and prolonged cholestatic reaction was found to be the vanishing bile duct syndrome with a marked transient pseudoxanthomatosis

Kristallstrukturbestimmung an einer Strontium-hydrid-imid-nitrid-Phase – Sr2(H)N/SrNH\mathrm{Sr_2(H)N/SrNH} bzw. Sr2(D)N/SrND\mathrm{Sr_2(D)N/SrND} – mit Röntgen-, Neutronen- und Synchrotron-Strahlung

Strontium reacts with nitrogen and hydrogen or deuterium under defined conditions to form a phase in which hydride, imide and nitride ions are present side by side.Sr is evaporated at 1000 ° C. The reaction with N 2 and H 2 or D 2 (p (N 2 ) = p (H 2 / D 2 ) = 50 mbar) takes place in the gas phase. The product crystallizes as orange-yellow or black crystal needles at 800 ° C.Neither from X-ray single crystal nor from X-ray or neutron diffraction powder data could the crystal structure be clearly determined. Only a high-resolution diffraction experiment with synchrotron radiation at the powder gave decisive indications for a structural model:Fractions of reflections can only be explained with a model in R 3 m with a = 3,870 (1) Å and c = 18,958 (3) Å. Additional reflections show that, in addition to Sr 2 (H), there are N regions with SrNH as the second phase. The refinement of neutron diffraction data (measurements at 2 K, 10 K, 300 K and 505 K) with a two-phase model Sr 2 (D) N / SrND leads to a meaningful result: in a slightly distorted cubic dense arrangement of Sr atoms occupy layers in Domains Hydride and nitride ions or imide ions Octahedral gaps completely and ordered to one third each