Implementing international environmental agreements in Russia

This exciting book is the first systematic study of how international environmental agreements are transformed into political action in Russia. Using three illuminating case studies on the implementation process in the fields of fisheries management, nuclear safety and air pollution control, this book fills an important gap in existing literature. While the focus in current social science debate on international environmental regimes is accumulating knowledge on 'implementing activities' at both national and international level, this book goes one step further and examines implementation at national and regional level. This topic is of great theoretical relevance to the study of environmental politics since some of the main sources of environmental degradation in Europe are to be found in the Russian Federation. It is also of relevance to the more general debate on contemporary Russian politics and offers valuable new material on regional politics in Russia. With its emphasis on the politics of environmental and resource management, it continues the description and discussion of political processes where most accounts of Russian politics tend to stop. This book will be invaluable for undergraduates, postgraduates and academics studying environmental politics and Russian politics at regional and national level

Implementing international environmental agreements in Russia

This exciting book is the first systematic study of how international environmental agreements are transformed into political action in Russia. Using three illuminating case studies on the implementation process in the fields of fisheries management, nuclear safety and air pollution control, this book fills an important gap in existing literature. While the focus in current social science debate on international environmental regimes is accumulating knowledge on 'implementing activities' at both national and international level, this book goes one step further and examines implementation at national and regional level. This topic is of great theoretical relevance to the study of environmental politics since some of the main sources of environmental degradation in Europe are to be found in the Russian Federation. It is also of relevance to the more general debate on contemporary Russian politics and offers valuable new material on regional politics in Russia. With its emphasis on the politics of environmental and resource management, it continues the description and discussion of political processes where most accounts of Russian politics tend to stop. This book will be invaluable for undergraduates, postgraduates and academics studying environmental politics and Russian politics at regional and national level

The Svalbard Fisheries Protection Zone: How Russia and Norway Manage an Arctic Dispute

Svalbard and the maritime zone around this Arctic archipelago are central to Norway–Russia rela-tions. Since 1977, a dispute has concerned Norway’s right to exercise jurisdiction over fisheries. What are Russian positions on Norwegian jurisdiction enforcement in the Fisheries Protection Zone (FPZ)? How have perceptions and reactions evolved since the turn of the millennium? Has the deterioration in the bilateral relationship post-2014 sharpened the dispute in the FPZ, and has the risk of conflict increased? We find that 2014 does not appear to be a watershed with respect to relations in the FPZ around Svalbard. After the dramatic arrest of a Russian trawler in 2005, the Russian central authorities switched from protest to relatively conciliatory dialogue — with a marked exception in 2011 related to Russian domestic discord surrounding the 2010 Barents Sea maritime boundary agreement. After 2011, incidents in the FPZ have been handled without further escalation, but the situation is underpinned by various factors that might change. Russia’s policies in the FPZ have been a balancing act: always stressing its official position and insisting that there are limitations to how much Norwegian enforcement can be accepted, while also ensuring that the enforcement regime survives

Divergent epigenetic responses to perinatal asphyxia in severe mental disorders

Epigenetic modifications influenced by environmental exposures are molecular sources of phenotypic heterogeneity found in schizophrenia and bipolar disorder and may contribute to shared etiopathogenetic mechanisms of these two disorders. Newborns who experienced perinatal asphyxia have suffered reduced oxygen delivery to the brain around the time of birth, which increases the risk of later psychiatric diagnosis. This study aimed to investigate DNA methylation in blood cells for associations with a history of perinatal asphyxia, a neurologically harmful condition occurring within the biological environment of birth. We utilized prospective data from the Medical Birth Registry of Norway to identify incidents of perinatal asphyxia in 643 individuals with schizophrenia or bipolar disorder and 676 healthy controls. We performed an epigenome wide association study to distinguish differentially methylated positions associated with perinatal asphyxia. We found an interaction between methylation and exposure to perinatal asphyxia on case–control status, wherein having a history of perinatal asphyxia was associated with an increase of methylation in healthy controls and a decrease of methylation in patients on 4 regions of DNA important for brain development and function. The differentially methylated regions were observed in genes involved in oligodendrocyte survival and axonal myelination and functional recovery (LINGO3); assembly, maturation and maintenance of the brain (BLCAP;NNAT and NANOS2) and axonal transport processes and neural plasticity (SLC2A14). These findings are consistent with the notion that an opposite epigenetic response to perinatal asphyxia, in patients compared with controls, may contribute to molecular mechanisms of risk for schizophrenia and bipolar disorder.publishedVersio

Health-related quality of life issues, including symptoms, in patients with active COVID-19 or post COVID-19; a systematic literature review

Purpose This systematic review was performed to identify all relevant health-related quality of life (HRQoL) issues associated with COVID-19. Methods A systematic literature search was undertaken in April 2020. In four teams of three reviewers each, all abstracts were independently reviewed for inclusion by two reviewers. Using a pre-defined checklist of 93 criteria for each publication, data extraction was performed independently by two reviewers and subsequently compared and discussed. If necessary, a third reviewer resolved any discrepancies. The search was updated in February 2021 to retrieve new publications on HRQoL issues including issues related to the long-term consequences of COVID-19. Results The search in April 2020 identified 3342 potentially relevant publications, and 339 publications were selected for full-text review and data extraction. We identified 75 distinct symptoms and other HRQoL issues categorized into 12 thematic areas; from general symptoms such as fever, myalgia, and fatigue, to neurological and psychological issues. The updated search revealed three extra issues experienced during active disease and long-term problems with fatigue, psychological issues and impaired cognitive function. Conclusion This first comprehensive systematic review provides a detailed overview of the wide range of HRQoL issues experienced by patients with COVID-19 throughout the course of the disease. It demonstrates the devastating impact of the disease and provides critically important information for clinicians, to enable them to better recognize the disease and to provide knowledge important for treatment and follow-up. The results provided the foundation for the international development of a COVID-19 specific patient-reported HRQoL questionnaire

The persistence of anti-Spike antibodies following two SARS-CoV-2 vaccine doses in patients on immunosuppressive therapy compared to healthy controls—a prospective cohort study

The durability of vaccine-induced humoral immunity against SARS-CoV-2 in patients with immune mediated inflammatory diseases (IMIDs) on immunosuppressive therapy is not known. The aim of this study was to compare the persistence of anti-Spike antibodies following two-dose SARS-CoV-2 vaccination between IMID patients and healthy controls and to identify factors associated with antibody decline.publishedVersio

Health-related quality of life in patients with COVID-19; international development of a patient-reported outcome measure

Background We aimed to create a questionnaire to assess the health-related quality of life including functioning, symptoms, and general health status of adult patients with current or previous COVID-19. Here, we report on Phase I and II of the development. Methods Internationally recognized methodology for questionnaire development was followed. In Phase I, a comprehensive literature review was performed to identify relevant COVID-19 issues. Decisions for inclusion, exclusion, and data extraction were completed independently in teams of two and then compared. The resulting issues were discussed with health care professionals (HCPs) and current and former COVID-19 patients. The input of HCPs and patients was carefully considered, and the list of issues updated. In Phase II, this updated list was operationalized into items/questions. Results The literature review yielded 3342 publications, 339 of which were selected for full-text review, and 75 issues were identified. Discussions with 44 HCPs from seven countries and 52 patients from six countries showed that psychological symptoms, worries, and reduced functioning lasted the longest for patients, and there were considerable discrepancies between HCPs and patients concerning the importance of some of the symptoms. The final list included 73 issues, which were operationalized into an 80-item questionnaire. Conclusion The resulting COVID-19 questionnaire covers health–related quality of life issues relevant to COVID-19 patients and is available in several languages. The next steps include testing of the applicability and patients’ acceptability of the questionnaire (Phase IIIA) and preliminary psychometric testing (Phase IIIB)

First results from the L3+C experiment at CERN

The L3+C experiment combines the high-precision spectrometer of the L3 detector at LEP, CERN, with a small air shower array. The momenta of cosmic ray induced muons can be measured from 20 to 2000 GeV/c. During the 1999 data taking period 5 billion muon events were recorded in the spectrometer. From April until mid Summer 2000 an additional 3 billion muon events have been recorded as well as 25 million air shower events. Here the first results on the muon momentum spectrum and charge ratio will be presented