Plant-Based Food for the Prevention of Type 2 Diabetes: Scoping Review

Type 2 Diabetes Mellitus (T2DM) is a chronic condition with growing worldwide prevalence. Besides genetic factors, a sedentary lifestyle, excess weight, and inadequate eating habits, characterized by an excess intake of refined carbohydrates and ultra-processed foods, are contributing factors for the development of the disease. In this scenario, promoting a plant-based diet, and limiting animal product consumption while increasing the intake of vegetables, concurrently with healthy lifestyle habits, is a promising strategy to prevent T2DM. This scoping review, carried out between 2017 and 2022, aimed to gather evidence substantiating the benefits of a plant-based diet in T2DM prevention, considering different eating patterns, such as vegetarian, vegan, Mediterranean, and DASH diets. Several studies demonstrate a significant reduction in T2DM incidence among individuals adopting plant-based eating patterns or emphasizing healthy plant-based food alongside decreased intake or exclusion of animal-based foods. There are still no robust data regarding plant-based diets and the prevention of diabetes without loss in body weight. Hence, prospective studies in plant-based diets with weight control are needed. Nevertheless, adopting plant-based diets appears to induce significant weight loss, which is crucial in an obesity-endemic context. Thus, embracing plant-based diets, along with healthy habits, emerges as a relevant strategy in obesity and T2DM prevention

STUDY OF THE PREVALENCE OF Capillaria hepatica IN HUMANS AND RODENTS IN AN URBAN AREA OF THE CITY OF PORTO VELHO, RONDÔNIA, BRAZIL

Introduction: Hepatic capillariosis, caused by Capillaria hepatica (Calodium hepaticum) (Bancroft, 1893), Travassos, 1915 (Nematoda, Trichinelloidea, Capillariidae), is a common zoonosis in rodents but is rare in humans. Seventy-two cases in humans have been reported worldwide since the first case was described by MACARTHUR in 192417,27. This study aimed to determine the prevalence of Capillaria hepatica in humans and rodents in an urban area of Porto Velho, the capital of Rondônia, in Brazil. Methods: After conducting a census of the area, 490 residents were randomly selected, and, after signing a term of consent, provided blood samples that were screened for anti-Capillaria hepatica antibodies. Simultaneously, rats were captured to assess the prevalence of this parasite in rodents by histopathological examination in liver sections. Results: A prevalence of 1.8% was found among residents who had specific antibodies at a dilution of 1:150, indicating exposure to parasite eggs; 0.8% of the subjects also had positive titers at a dilution of 1:400, indicating true infection. The prevalence in rats was 2%. Conclusions: The prevalence of infection with this parasite among humans and rats was low. While the prevalence encountered among humans was within the limits reported in the literature, the prevalence among rodents was much lower.Introdução: Capilaríase hepática é causada pela Capillaria hepatica (syn. Calodium hepaticum) (Bancroft, 1893), Travassos, 1915 (Nematoda, Trichinelloidea, Capillariidae), sendo uma zoonose comum entre roedores, porém rara em humanos. Setenta e dois casos humanos foram relatados na literatura mundial desde o primeiro caso descrito por MACARTHUR em 192417,27. O objetivo desse estudo é determinar a prevalência da Capillaria hepatica em humanos e roedores de área urbana da cidade de Porto Velho, capital de Rondônia, Brasil. Método: Após realizar um censo da área, 490 moradores foram aleatoriamente selecionados e assinaram termo de consentimento, foram colhidas amostras de sangue para testar anticorpos anti-Capillaria hepatica. Simultaneamente, ratos foram capturados para determinação da prevalência deste parasita através do exame histopatológico em cortes de fígado. Resultados: Foi encontrada entre humanos prevalência de 1,8% de positividade para anticorpos específicos em diluição de 1:150, indicando exposição aos ovos do parasito; 0,8% desses também deram testes positivos quando seus soros sofreram diluição de 1:400, indicando infecção verdadeira. Nos ratos, a prevalência foi de 2%. Conclusão: A prevalência encontrada para o parasito entre homens e roedores foi baixa. Enquanto a prevalência encontrada entre humanos esteve dentro dos limites encontrados na literatura, a prevalência entre roedores foi bem menor

Study of the prevalence of Capillaria hepatica in humans and rodents in an urban area of the city of Porto Velho, Rondônia, Brazil.

Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2015-03-17T13:53:36Z No. of bitstreams: 1 Rocha EJG Study of the....pdf: 138873 bytes, checksum: 3aec7ed9947017e8611f434127d5f363 (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2015-03-17T13:53:47Z (GMT) No. of bitstreams: 1 Rocha EJG Study of the....pdf: 138873 bytes, checksum: 3aec7ed9947017e8611f434127d5f363 (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2015-03-17T14:10:11Z (GMT) No. of bitstreams: 1 Rocha EJG Study of the....pdf: 138873 bytes, checksum: 3aec7ed9947017e8611f434127d5f363 (MD5)Made available in DSpace on 2015-03-17T14:10:11Z (GMT). No. of bitstreams: 1 Rocha EJG Study of the....pdf: 138873 bytes, checksum: 3aec7ed9947017e8611f434127d5f363 (MD5) Previous issue date: 2015Faculdade São Lucas. Porto Velho, RO, BrasilFaculdade São Lucas. Porto Velho, RO, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, BrasilLaboratório Central de Saúde Pública de Rondônia. LACEN/RO. Porto Velho, RO, BrasilUnB Universidade de Brasília. Hospital Universitário. Laboratório de Patologia Veterinária. Brasília, DF, BrasilUniversidade Federal de Mato Grosso. Faculdade de Agronomia e Medicina Veterinária. Departamento de Clínica Médica Veterinária. Cuiabá, MG, BrasilFaculdade São Lucas. Porto Velho, RO, BrasilFaculdade São Lucas. Porto Velho, RO, BrasilFaculdade São Lucas. Porto Velho, RO, BrasilUniversity of Sao Paulo. Porto Velho, RO, BrasilIntroduction: Hepatic capillariosis, caused by Capillaria hepatica (Calodium hepaticum) (Bancroft, 1893), Travassos, 1915 (Nematoda, Trichinelloidea, Capillariidae), is a common zoonosis in rodents but is rare in humans. Seventy-two cases in humans have been reported worldwide since the first case was described by MACARTHUR in 192417,27. This study aimed to determine the prevalence of Capillaria hepatica in humans and rodents in an urban area of Porto Velho, the capital of Rondônia, in Brazil. Methods: After conducting a census of the area, 490 residents were randomly selected, and, after signing a term of consent, provided blood samples that were screened for anti-Capillaria hepatica antibodies. Simultaneously, rats were captured to assess the prevalence of this parasite in rodents by histopathological examination in liver sections. Results: A prevalence of 1.8% was found among residents who had specific antibodies at a dilution of 1:150, indicating exposure to parasite eggs; 0.8% of the subjects also had positive titers at a dilution of 1:400, indicating true infection. The prevalence in rats was 2%. Conclusions: The prevalence of infection with this parasite among humans and rats was low. While the prevalence encountered among humans was within the limits reported in the literature, the prevalence among rodents was much lower. KEYWORDS: Capillariasis; Capillaria hepatica; Rondônia

Epidemiological aspects of Toxoplasma gondii infection in riverside communities in the Southern Brazilian Amazon

INTRODUCTION: Toxoplasma gondii infection is widely prevalent in humans and other animals worldwide. Information on the prevalence of T. gondii infection is scarce in some regions of Brazil, including riverside communities along the Amazon River basin. M METHODS: The prevalence of T. gondii in 231 people, aged 1-85 years, who were living in four riverside communities along the Purus River, L&#225;brea, State of Amazonas, Brazil, was determined. Antibodies against T. gondii were assayed using a commercial enzyme-linked immunosorbent assay (ELISA) kit. The hearts and brains of 50 chickens, which were raised free-range in the communities, were pooled according to the community of origin and bioassayed in mice. The isolates were genotyped using polymorphisms at 12 nuclear markers (SAG1, 5' and 3'-SAG2, alt.SAG2, SAG3, BTUB, GRA6, c22-8, c29-2, L358, PK1, Apico and CS3). RESULTS: The overall seroprevalence of T. gondii was 56.7% (131/231). IgG antibodies were presented by 117 (89.3%) and IgM by 14 (10.7%) of the 131 positive individuals. No association between age group and gender with prevalence was observed (chi-square test, p > 0.05); however, the comparison between localities showed that the seroprevalence of T. gondii was significantly lower among the individuals living in the Boca do Ituxi (p < 0.05) community. Five isolates of T. gondii were obtained in the mouse bioassay, and genotyping revealed two complete genotypes that had not been described previously and three mixed isolates. CONCLUSIONS: These results support previous findings that T. gondii population genetics are highly diverse in Brazil and that T. gondii infection is active in these riverside communities