29 research outputs found

    The OCaml system release 5.0: Documentation and user's manual

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    This manual documents the release 5.0 of the OCaml system. It is organized as follows. Part I, "An introduction to OCaml", gives an overview of the language. Part II, "The OCaml language", is the reference description of the language. Part III, "The OCaml tools", documents the compilers, toplevel system, and programming utilities. Part IV, "The OCaml library", describes the modules provided in the standard library. Part V, “Indexes”, contains an index of all identifiers defined in the standard library, and an index of keywords

    Analyse écorégionale marine de Nouvelle-Calédonie : atelier d'identification des aires de conservation prioritaires

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    Dans le cadre de l'initiative pour les rĂ©cifs coralliens du Pacifique sud (CRISP), le WWF-France a souhaitĂ© dĂ©velopper un projet pour la protection des rĂ©cifs et des lagons nĂ©o-calĂ©doniens. L'atelier, qui s'est dĂ©roulĂ© les 10 et 11 aoĂ»t Ă  NoumĂ©a, avait pour objectif de rassembler les scientifiques et les experts du lagon nĂ©ocalĂ©donien pour identifier, sur la base de leur connaissance experte, les zones les plus remarquables du lagon (richesse, endĂ©misme, originalitĂ© des faunes et flores, espĂšces emblĂ©matiques, zones d'intĂ©rĂȘt fonctionnel) sur lesquelles doivent porter en prioritĂ© les efforts de conservation. Il a permis d'identifier 20 aires prioritaires pour la conservation, parmi lesquelles 6 ont un intĂ©rĂȘt mondial, 4 ont un intĂ©rĂȘt sur le plan rĂ©gional, les autres ayant un intĂ©rĂȘt local

    Parkin Deficiency Delays Motor Decline and Disease Manifestation in a Mouse Model of Synucleinopathy

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    In synucleinopathies, including Parkinson's disease, partially ubiquitylated α-synuclein species phosphorylated on serine 129 (PS129-α-synuclein) accumulate abnormally. Parkin, an ubiquitin-protein ligase that is dysfunctional in autosomal recessive parkinsonism, protects against α-synuclein-mediated toxicity in various models
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