Finding the Right Technology to Support Learning Outcomes

This 90-minute seminar, led by Ike Shibley, PhD, offers proven strategies for technology to increase flexibility and access, improve student performance, and manage costs. Ivan A. Shibley, Jr. (Ike), Ph.D., is associate professor of chemistry at Penn State Berks, a small four-year college within the Penn State system. He has won both local and university-wide awards for his teaching including the Eisenhower Award presented to a tenured Penn State faculty member who exhibits excellent teaching as well as mentoring other teachers. Ike became involved in blended learning as part of an 18-month project to completely redesign the general chemistry course at Berks. As part of a team of six professionals who invested over 1,000 man-hours in the redesign Ike helped provide the pedagogical and subject matter expertise to help guide the redesign. The course has now been delivered in a blended format for three years with an average GPA almost 25% higher than previous years. Ike has taught the three sections of the course and is currently co-author- ing a manuscript about the results. Ike recently redesigned a nutrition course that was taught in a blended format that met only half the number of hours of a traditional course with comparable grades. He has presented his work on blended learning at numerous professional conferences and has become an advocate of blended learning.https://knowledge.e.southern.edu/onlineseminars/1007/thumbnail.jp

In Blended Courses, What Should Students Do Online?

This presentation gives teachers advice on what to do in blended classrooms and what resources to use in their online classrooms. Ike Shibley, is an assistant professor, associate professor of chemistry at the Penn State Berks campus. Tim Wilson is an assistant professor at the University of Western Ontario in anatomy and cell biology.https://knowledge.e.southern.edu/onlineseminars/1023/thumbnail.jp

Deoxyguanosine-resistant Leukemia L1210 Cells: Loss of Specific Deoxyribonecleoside Kinase Activity

A mouse leukemia L1210 cell line was selected for resistance to deoxyguanosine. The deoxyguanosine-resistant cells (dGuo-R) were 126-fold less sensitive to deoxyguanosine than the wild-type cells. The IC50 values for araC and araG were increased, but only 10-12-fold in the dGuo- R cells when compared with the wild-type cells. The dGuo-R cell line showed an increased level of resistance to 2-fluoro-2'-deoxyadenosine and 2-fluoroadenine arabinoside (11-14-fold), but essentially no increase in resistance to deoxyadenosine or adenine arabinoside. Deoxyribonucleoside kinase activity was decreased only slightly (19%) when deoxycytidine was utilized as substrate; when cytosine arabinoside or deoxyguanosine was used as the substrate, the kinase activity in the extracts from the dGuo-R cells was only 10% of the enzyme activity in the extracts from the wild-type cells. The determination of the kinetic parameters, Km and Vmax, indicated that there were marked decreases in the Vmax values for deoxyguanosine and cytosine arabinoside as substrates, but not for deoxycytidine as substrate; the Km values for deoxycytidine and cytosine arabinoside were increased in the extracts from the dGuo-R cells. By use of high-performance liquid chromatography, the kinase activities in the extracts from the wild-type and resistant cells could be resolved. There was the specific loss of kinase activity toward cytosine arabinoside and deoxyguanosine as substrates. These data indicate that the dGuo-R cells have decreased levels of a specific deoxyribonucleoside kinase activity. Originally published Journal of Biological Chemistry, Vol. 268, No. 1, Jan 199

23 Practical Strategies to Help New Faculty Thrive

In 23 Practical Strategies to Help New Faculty Thrive, award-winning professor Ike Shibley will fill this training gap by explaining how new college professors can sharpen their pedagogical skills while avoiding common errors and teaching traps. Ivan A. Shibley, Jr. (Ike) is associate professor of chemistry at Penn State Berks, a small four-year college within the Penn State system. He received his B.S. in chemical engineering from the University of Pittsburgh and his Ph.D. in biochemistry from East Carolina University. Between undergraduate and graduate school he spent four years in the Navy where he taught nuclear physics and radiation safety. He now teaches introductory chemistry, general chemistry, organic chemistry, biochemistry, philosophy of science courses, first-year bioethics seminar, and senior sci- ence seminar. His research involves pedagogical approaches to improving science instruction at thecollege level. He has won both local and university-wide awards for his teaching including theEisenhower Award presented to a tenured Penn State faculty member who exhibits excellent teach- ing as well as mentoring other teachers.https://knowledge.e.southern.edu/onlineseminars/1000/thumbnail.jp