EFFECT OF DRYING ON POWDER COATING EFFICIENCY AND AGGLOMERATION IN VIBRO-FLUIDIZED BED

Glass beads of 43 m were coated in a vibro-fluidized bed by atomizing a fine silica powder together with polyvinyl alcohol aqueous solution. The coating efficiency and weight fraction of the agglomerated particles were measured under various experimental conditions, and their dependencies on the frequency and the direction of vibration were investigated. The coating efficiency and the degree of the agglomeration among core particles correlated well with an index R. The index R was introduced to evaluate quantitatively the drying conditions in a fluidized bed. Application of vertical vibration on the fluidized bed lowered the coating efficiency somewhat, while it prevented agglomeration. From the experimental results it was confirmed that coating with high quality and high efficiency, where few agglomerates were produced and silica powder was utilized efficiently, was possible in a vibro-fluidized bed with adequate vibration frequency and orientation of the vibration vector

Effect of Drying on Powder Coating Efficiency and Agglomeration in Vibro-Fluidized Bed

Glass beads of 43 m were coated in a vibro-fluidized bed by atomizing a fine silica powder together with polyvinyl alcohol aqueous solution. The coating efficiency and weight fraction of the agglomerated particles were measured under various experimental conditions, and their dependencies on the frequency and the direction of vibration were investigated. The coating efficiency and the degree of the agglomeration among core particles correlated well with an index R. The index R was introduced to evaluate quantitatively the drying conditions in a fluidized bed. Application of vertical vibration on the fluidized bed lowered the coating efficiency somewhat, while it prevented agglomeration. From the experimental results it was confirmed that coating with high quality and high efficiency, where few agglomerates were produced and silica powder was utilized efficiently, was possible in a vibro-fluidized bed with adequate vibration frequency and orientation of the vibration vector

High glucose concentration-induced expression of pentraxin-3 in a rat model of continuous peritoneal dialysis

Background: Continuous exposure to peritoneal dialysis fluids (PDFs) is associated with pathological responses such as persistent microinflammation, which leads to ultrafiltration failure. Pentraxin-3 (PTX3), a multifunctional soluble pattern recognition receptor, is produced at sites of inflammation by a wide range of cell types. This study investigates the in vivo expression of PTX3 in the peritoneal membrane of a rat continuous peritoneal dialysis (PD) model, as well as the effect of high glucose on the in vitro expression of PTX3. Methods: The expression of PTX3 was analyzed using RT-PCR, real-time PCR, immunohistochemistry and western blotting in a PD rat model receiving saline or conventional PDF containing 3.86% glucose for 8 weeks. The effects of high glucose on the expression of PTX3 were examined in cultured rat peritoneal mesothelial cells (RPMCs), mouse macrophage-like cells, and mouse fibroblasts. Results: In a rat model of PD, eight-week instillation of the conventional PDF produced increased submesothelial thickening, followed by substantially enhanced PTX3 protein levels in the submesothelial layer of peritoneal membrane. PTX3 was detected in peritoneal mesothelial cells, macrophages and fibroblasts in the thickened submesothelial area. Glucose was found to induce PTX3 protein expression in RPMCs as well as macrophage-like cells and fibroblasts. Conclusion: Continuous exposure to conventional PDF induces PTX3 expression in the peritoneal membrane of rats. High glucose may be involved in the mechanism of PDF-induced local micro-inflammation in the peritoneum