5 research outputs found

    Ranibizumab for the treatment of degenerative ocular conditions

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    Magdalini Triantafylla,1 Horace F Massa,2 Doukas Dardabounis,1 Zisis Gatzioufas,2 Vassilios Kozobolis,1 Konstantinos Ioannakis,1 Irfan Perente,1,3 Georgios D Panos1,21Department of Ophthalmology, University General Hospital of Alexandroupolis, School of Medicine, University of Thrace, Alexandroupolis, Greece; 2Department of Ophthalmology, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Switzerland; 3Beyoglou Eye Research and Teaching Hospital, Istanbul University, Istanbul, TurkeyAbstract: Degenerative ocular conditions, such as age-related macular degeneration, diabetic retinopathy, retinal vein occlusions, and myopic degeneration, have become a major public health problem and a leading cause of blindness in developed countries. Anti-vascular endothelial growth factor (VEGF) drugs seem to be an effective and safe treatment for these conditions. Ranibizumab, a humanized monoclonal antibody antigen-binding fragment, which inhibits all biologically active isoforms of VEGF-A, is still the gold standard treatment for the majority of these pathological entities. In this review, we present the results of the most important clinical trials concerning the efficacy and safety of ranibizumab for the treatment of degenerative ocular conditions.Keywords: age-related macular degeneration, diabetic macular edema, retinal vein occlusion, anti-VEGF, safety, efficacy, quality of lif

    SHREC'16 track: partial shape queries for 3D object retrieval

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    Despite numerous recent efforts, 3D object retrieval based on partial shape queries remains a challenging problem, far from being solved. The problem can be defined as: given a partial view of a shape as query, retrieve all partially similar 3D models from a repository. The objective of this track is to evaluate the performance of partial 3D object retrieval methods, for partial shape queries of various scan qualities and degrees of partiality. The retrieval problem is often found in cultural heritage applications, for which partial scans of objects query a dataset of geometrically distinct classes

    SHREC'16 track: partial shape queries for 3D object retrieval

    No full text
    Despite numerous recent efforts, 3D object retrieval based on partial shape queries remains a challenging problem, far from being solved. The problem can be defined as: given a partial view of a shape as query, retrieve all partially similar 3D models from a repository. The objective of this track is to evaluate the performance of partial 3D object retrieval methods, for partial shape queries of various scan qualities and degrees of partiality. The retrieval problem is often found in cultural heritage applications, for which partial scans of objects query a dataset of geometrically distinct classes
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