Sensitive determination of uric acid at layered zinc hydroxide-sodium dodecyl sulphate-propoxur nanocomposite

An electrochemical chemical sensor for the determination of uric acid (UA) with high sen­si­ti­vity and a wide working range was fabricated using the layered zinc hydroxide-sodium dode­cyl sulphate-propoxur (LZH-SDS-PRO) nanocomposite, modified with multi­wall carbon nano­tu­bes (MWCNT). The introduction of LZH-SDS-PRO as a conducting matrix has en­hanced the con­ductivity of MWCNT. The morphology of LZH-SDS-PRO/MWCNT was cha­rac­terized by trans­mission electron microscopy (TEM) and scanning electron micro­scopy (SEM), while electro­chemical behavior of UA and K3[Fe(CN)6] at LZH-SDS-PRO/MWCNT paste electrode was studied by square wave and cyclic voltammetry, respect­tively. Under the opti­mized ex­peri­mental conditions, the electrode established linear plot for UA con­centrations 7.0 mol L-1 to 0.7 mmol L-1 (R2 = 0.9920) and LOD was calculated to be 4.28 µmol L-1 (S/N = 3). The fabri­ca­ted LZH-SDS-PRO/MWCNT electrode was success­sfully applied to urine samples, exhi­bi­t­ing excellent stability and reproducibility, which made it worthwhile for analytical applica­tions

Sensitive determination of uric acid at layered zinc hydroxide-sodium dodecyl sulphate-propoxur nanocomposite

An electrochemical chemical sensor for the determination of uric acid (UA) with high sen­si­ti­vity and a wide working range was fabricated using the layered zinc hydroxide-sodium dode­cyl sulphate-propoxur (LZH-SDS-PRO) nanocomposite, modified with multi­wall carbon nano­tu­bes (MWCNT). The introduction of LZH-SDS-PRO as a conducting matrix has en­hanced the con­ductivity of MWCNT. The morphology of LZH-SDS-PRO/MWCNT was cha­rac­terized by trans­mission electron microscopy (TEM) and scanning electron micro­scopy (SEM), while electro­chemical behavior of UA and K3[Fe(CN)6] at LZH-SDS-PRO/MWCNT paste electrode was studied by square wave and cyclic voltammetry, respect­tively. Under the opti­mized ex­peri­mental conditions, the electrode established linear plot for UA con­centrations 7.0 mol L-1 to 0.7 mmol L-1 (R2 = 0.9920) and LOD was calculated to be 4.28 µmol L-1 (S/N = 3). The fabri­ca­ted LZH-SDS-PRO/MWCNT electrode was success­sfully applied to urine samples, exhi­bi­t­ing excellent stability and reproducibility, which made it worthwhile for analytical applica­tions