26 research outputs found
Topical Imiquimod for Management of Recurrent Lentigo Maligna Melanoma in Situ
Topical imiquimod is a medication approved for the treatment
of external genital and perianal warts, actinic keratosis, and superficial basal
cell carcinoma. There have also been reports of its successful use in patients
with lentigo maligna melanoma in situ. An 80-year-old female patient was
diagnosed with lentigo maligna melanoma in situ which was then surgically
removed. After several recurrences, nonsurgical treatment using topical 5%
imiquimod was introduced. At 9-month follow-up the skin was completely
healed with no evidence of cancer recurrence. In select cases, topical imiquimod
seems to be an effective alternative to surgical treatment of melanoma
in situ (MIS). Further studies are necessary to assess the successfulness of this
treatment method
Malignant melanoma in childhood
Maligni melanom je v otroÅ”ki dobi zelo redka oblika malignega obolenja. Zanesljiva diagnoza pomeni izziv tako za kliniko kot za patohistologa. Äeprav oba postavita diagnozo melanom silno redko gre kljub vsemu nemalokrat v resnici za benigno pigmentno spremembo. Nekateri podatki in vpraÅ”anja v zvezi z melanomi v otroÅ”tvu so obravnavani v prispevku.Malignant melanoma in childhood is a very rare malignancy. The accurate diagnosis of melanoma in infants and children present a challenging problem for clinicians and pathologists. It is often "overdiagnosed". Some datas and questions are disscussed