Motional Broadening in Ensembles With Heavy-Tail Frequency Distribution

We show that the spectrum of an ensemble of two-level systems can be broadened through `resetting' discrete fluctuations, in contrast to the well-known motional-narrowing effect. We establish that the condition for the onset of motional broadening is that the ensemble frequency distribution has heavy tails with a diverging first moment. We find that the asymptotic motional-broadened lineshape is a Lorentzian, and derive an expression for its width. We explain why motional broadening persists up to some fluctuation rate, even when there is a physical upper cutoff to the frequency distribution.Comment: 6 pages, 4 figure

Direct Measurement of the System-Environment Coupling as a Tool For Understanding Decoherence and Dynamical Decoupling

Decoherence is a major obstacle to any practical implementation of quantum information processing. One of the leading strategies to reduce decoherence is dynamical decoupling --- the use of an external field to average out the effect of the environment. The decoherence rate under any control field can be calculated if the spectrum of the coupling to the environment is known. We present a direct measurement of the bath coupling spectrum in an ensemble of optically trapped ultracold atoms, by applying a spectrally narrow-band control field. The measured spectrum follows a Lorentzian shape at low frequencies, but exhibits non-monotonic features at higher frequencies due to the oscillatory motion of the atoms in the trap. These features agree with our analytical models and numerical Monte-Carlo simulations of the collisional bath. From the inferred bath-coupling spectrum, we predict the performance of well-known dynamical decoupling sequences: CPMG, UDD and CDD. We then apply these sequences in experiment and compare the results to predictions, finding good agreement in the weak-coupling limit. Thus, our work establishes experimentally the validity of the overlap integral formalism, and is an important step towards the implementation of an optimal dynamical decoupling sequence for a given measured bath spectrum.Comment: 9 pages, 6 figure

Caught in the act: the lifetime of synaptic intermediates during the search for homology on DNA

Homologous recombination plays pivotal roles in DNA repair and in the generation of genetic diversity. To locate homologous target sequences at which strand exchange can occur within a timescale that a cell’s biology demands, a single-stranded DNA-recombinase complex must search among a large number of sequences on a genome by forming synapses with chromosomal segments of DNA. A key element in the search is the time it takes for the two sequences of DNA to be compared, i.e. the synapse lifetime. Here, we visualize for the first time fluorescently tagged individual synapses formed by RecA, a prokaryotic recombinase, and measure their lifetime as a function of synapse length and differences in sequence between the participating DNAs. Surprisingly, lifetimes can be ∼10 s long when the DNAs are fully heterologous, and much longer for partial homology, consistently with ensemble FRET measurements. Synapse lifetime increases rapidly as the length of a region of full homology at either the 3′- or 5′-ends of the invading single-stranded DNA increases above 30 bases. A few mismatches can reduce dramatically the lifetime of synapses formed with nearly homologous DNAs. These results suggest the need for facilitated homology search mechanisms to locate homology successfully within the timescales observed in vivo

Towards the Crowdsourcing of Massive Smartphone Assisted-GPS Sensor Ground Observations for the Production of Digital Terrain Models

Digital Terrain Models (DTMs) used for the representation of the bare earth are produced from elevation data obtained using high-end mapping platforms and technologies. These require the handling of complex post-processing performed by authoritative and commercial mapping agencies. In this research, we aim to exploit user-generated data to produce DTMs by handling massive volumes of position and elevation data collected using ubiquitous smartphone devices equipped with Assisted-GPS sensors. As massive position and elevation data are collected passively and straightforwardly by pedestrians, cyclists, and drivers, it can be transformed into valuable topographic information. Specifically, in dense and concealed built and vegetated areas, where other technologies fail, handheld devices have an advantage. Still, Assisted-GPS measurements are not as accurate as high-end technologies, requiring pre- and post-processing of observations. We propose the development and implementation of a 2D Kalman filter and smoothing on the acquired crowdsourced observations for topographic representation production. When compared to an authoritative DTM, results obtained are very promising in producing good elevation values. Today, open-source mapping infrastructures, such as OpenStreetMap, rely primarily on the global authoritative SRTM (Shuttle Radar Topography Mission), which shows similar accuracy but inferior resolution when compared to the results obtained in this research. Accordingly, our crowdsourced methodology has the capacity for reliable topographic representation production that is based on ubiquitous volunteered user-generated data

Silent voices that must be heard – women’s perceptions of gynecologic examinations

Purpose To analyze the perception of gynecologic examination from the patients’ point of view. Materials and methods This anonymous electronic cross-sectional survey aimed to evaluate the subjective experiences of women during gynecologic examinations (levels of pain, embarrassment and trauma), the manner the examination was conducted, and women’s suggestions for improving their experience. Results Overall, 6,508 women answered the survey. The examination was considered an embarrassing event by 47%, painful by 35% and traumatic by 19%. Importantly, only 43% of the respondents stated they would notify the gynecologist in case of physical discomfort or pain during the examination. The quality of physician-to-patient communication was rated as the most important aspect of gynecologic examination, and showed a significant association with the general quality of the experience (levels of pain, embarrassment, and trauma). Matters relating to women’s privacy during gynecologic examination were also considered important. An option for a companion was rated as important by 64% of the respondents. Significant differences with large effect-sizes were found between the respondents’ preferences and their reports of the observed situation. Conclusion The findings highlight the need for establishing guidelines for gynecologic examinations, according to a patient-centered care approach. This study constitutes a first discourse on the subject of gynecologic examinations in Israel in order to provide an overview and initial insights, serving as a starting point for further specific and more in-depth research

Design principles of biologically fabricated avian nests

Abstract Materials and construction methods of nests vary between bird species and at present, very little is known about the relationships between architecture and function in these structures. This study combines computational and experimental techniques to study the structural biology of nests fabricated by the edible nest swiftlet Aerodramus fuciphagus on vertical rock walls using threaded saliva. Utilizing its own saliva as a construction material allows the swiftlets full control over the structural features at a very high resolution in a process similar to additive manufacturing. It was hypothesized that the mechanical properties would vary between the structural regions of the nest (i.e. anchoring to the wall, center of the cup, and rim) mainly by means of architecture to offer structural support and bear the natural loads of birds and eggs. We generated numerical models of swiftlet nests from μCT scans based on collected swiftlet nests, which we loaded with a force of birds and eggs. This was done in order to study and assess the stress distribution that characterizes the specific nest’s architecture, evaluate its strength and weak points if any, as well as to understand the rationale and benefits that underlie this natural structure. We show that macro- and micro-scale structural patterns are identical in all nests, suggesting that their construction is governed by specific design principles. The nests’ response to applied loads of birds and eggs in finite element simulations suggests a mechanical overdesign strategy, which ensures the stresses experienced by its components in any loading scenario are actively minimized to be significantly smaller than the tensile fracture strength of the nests’ material. These findings highlight mechanical overdesign as a biological strategy for resilient, single-material constructions designed to protect eggs and hatchlings