コウケツアツシゼンハッショウラットノマッショウドウミャクノケイタイガクテキケンキュウ

京都大学0048新制・課程博士医学博士甲第1216号医博第407号新制||医||164B(附属図書館)3231UT51-47-G20京都大学大学院医学研究科病理系専攻(主査)教授 翠川 修, 教授 岡本 耕造, 教授 尾曽 越文亮学位規則第5条第1項該当Kyoto UniversityDA

A CASE OF MALIGNANT RENAL NEOPLASM WITH RHABDOID FEATURES IN AN ADULT

We report a case of malignant neoplasm with rhabdoid features of the kidney in a 68 year old man. To our knowledge malignant rhabdoid tumor of the kidney (MRTK) has been limited to the pediatric age group. Malignant renal neoplasm similar to MRTK occurring in adults is very rare. However, there has been a recent review in which the authors found 23/480 cases of renal cell carcinoma (RCC) (4.7%) exhibiting rhabdoid features, all in adults. In the present case, examination of many sections of tumor-affected tissue revealed no sign of any other malignant tumor included RCC, so-called pure adult malignant rhabdoid tumor in the kidney. MRTK does not respond well to aggressive chemotherapy regimens and survival tends to be short. This patient remains alive with no metastasis and local recurrence more than 45 months from the operation without adjuvant therapy