Quasistatic computing environments

Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1996.Includes bibliographical references (p. 55-57).by Ian S. Eslick.M.Eng

Searching for commonsense

Thesis (S.M.)--Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2006.Includes bibliographical references (leaves 97-101).Acquiring and representing the large body of "common sense" knowledge underlying ordinary human reasoning and communication is a long standing problem in the field of artificial intelligence. This thesis will address the question whether a significant quantity of this knowledge may be acquired by mining natural language content on the Web. Specifically, this thesis emphasizes the representation of knowledge in the form of binary semantic relationships, such as cause, effect, intent, and time, among natural language phrases. The central hypothesis is that seed knowledge collected from volunteers enables automated acquisition of this knowledge from a large, unannotated, general corpus like the Web. A text mining system, ConceptMiner, was developed to evaluate this hypothesis. ConceptMiner leverages web search engines, Information Extraction techniques and the ConceptNet toolkit to analyze Web content for textual evidence indicating common sense relationships.(cont.) Experiments are reported for three semantic relation classes: desire, effect, and capability. A Pointwise Mutual Infomation measure computed from Web hit counts is demonstrated to filter general common sense from instance knowledge true only in specific circumstances. A semantic distance metric is introduced which significantly reduces negative instances from the extracted hypotheses. The results confirm that significant relational common sense knowledge exists on the Web and provides evidence that the algorithms employed by ConceptMiner can extract this knowledge with a precision approaching that provided by human subjects.by Ian Scott Eslick.S.M

Severe Lumbar Disability Is Associated With Decreased Psoas Cross-Sectional Area in Degenerative Spondylolisthesis

Study Design: Retrospective cohort. Objectives: Alterations in lumbar paraspinal muscle cross-sectional area (CSA) may correlate with lumbar pathology. The purpose of this study was to compare paraspinal CSA in patients with degenerative spondylolisthesis and severe lumbar disability to those with mild or moderate lumbar disability, as determined by the Oswestry Disability Index (ODI). Methods: We retrospectively reviewed the medical records of 101 patients undergoing lumbar fusion for degenerative spondylolisthesis. Patients were divided into ODI score ≤40 (mild/moderate disability, MMD) and ODI score \u3e40 (severe disability, SD) groups. The total CSA of the psoas and paraspinal muscles were measured on preoperative magnetic resonance imaging (MRI). Results: There were 37 patients in the SD group and 64 in the MMD group. Average age and body mass index were similar between groups. For the paraspinal muscles, we were unable to demonstrate any significant differences in total CSA between the groups. Psoas muscle CSA was significantly decreased in the SD group compared with the MMD group (1010.08 vs 1178.6 mm2, P =.041). Multivariate analysis found that psoas CSA in the upper quartile was significantly protective against severe disability (P =.013). Conclusions: We found that patients with severe lumbar disability had no significant differences in posterior lumbar paraspinal CSA when compared with those with mild/moderate disability. However, severely disabled patients had significantly decreased psoas CSA, and larger psoas CSA was strongly protective against severe disability, suggestive of a potential association with psoas atrophy and worsening severity of lumbar pathology. © The Author(s) 2018

School Counseling Faculty Perceptions and Experiences Preparing Elementary School Counselors

School counselors’ job roles and preferences reportedly vary by educational level (i.e., elementary, middle and high school); however, several organizations, such as the American School Counselor Association, conceptualize and recommend school counseling practice and preparation through a K–12 lens. Little is known about how or if school counseling faculty members vary their preparation for specific educational levels. In this article, we discuss a national, mixed methods study of school counseling faculty (N = 132) experiences and perceptions regarding school counselor preparation for the elementary level. We focused on elementary school counselors due to their unique roles. Findings included faculty’s varied experiences and perceptions of differentiation, prioritizing a K–12 preparation focus, and several external factors driving their preparation such as state licensure and mandates, school counseling job opportunities, and student enrollment, motivation and interest in elementary school counseling

HEALTH GeoJunction: place-time-concept browsing of health publications

<p>Abstract</p> <p>Background</p> <p>The volume of health science publications is escalating rapidly. Thus, keeping up with developments is becoming harder as is the task of finding important cross-domain connections. When geographic location is a relevant component of research reported in publications, these tasks are more difficult because standard search and indexing facilities have limited or no ability to identify geographic foci in documents. This paper introduces <it><smcaps>HEALTH</smcaps> GeoJunction</it>, a web application that supports researchers in the task of quickly finding scientific publications that are relevant geographically and temporally as well as thematically.</p> <p>Results</p> <p><it><smcaps>HEALTH</smcaps> GeoJunction </it>is a geovisual analytics-enabled web application providing: (a) web services using computational reasoning methods to extract place-time-concept information from bibliographic data for documents and (b) visually-enabled place-time-concept query, filtering, and contextualizing tools that apply to both the documents and their extracted content. This paper focuses specifically on strategies for visually-enabled, iterative, facet-like, place-time-concept filtering that allows analysts to quickly drill down to scientific findings of interest in PubMed abstracts and to explore relations among abstracts and extracted concepts in place and time. The approach enables analysts to: find publications without knowing all relevant query parameters, recognize unanticipated geographic relations within and among documents in multiple health domains, identify the thematic emphasis of research targeting particular places, notice changes in concepts over time, and notice changes in places where concepts are emphasized.</p> <p>Conclusions</p> <p>PubMed is a database of over 19 million biomedical abstracts and citations maintained by the National Center for Biotechnology Information; achieving quick filtering is an important contribution due to the database size. Including geography in filters is important due to rapidly escalating attention to geographic factors in public health. The implementation of mechanisms for iterative place-time-concept filtering makes it possible to narrow searches efficiently and quickly from thousands of documents to a small subset that meet place-time-concept constraints. Support for a <it>more-like-this </it>query creates the potential to identify unexpected connections across diverse areas of research. Multi-view visualization methods support understanding of the place, time, and concept components of document collections and enable comparison of filtered query results to the full set of publications.</p

RNA interference in marine and freshwater sponges

Background: The marine sponge Tethya wilhelma and the freshwater sponge Ephydatia muelleri are emerging model organisms to study evolution, gene regulation, development, and physiology in non-bilaterian animal systems. Thus far, functional methods (i.e., loss or gain of function) for these organisms have not been available. Results: We show that soaking developing freshwater sponges in double-stranded RNA and/or feeding marine and freshwater sponges bacteria expressing double-stranded RNA can lead to RNA interference and reduction of targeted transcript levels. These methods, first utilized in C. elegans, have been adapted for the development and feeding style of easily cultured marine and freshwater poriferans. We demonstrate phenotypic changes result from ‘knocking down’ expression of the actin gene. Conclusion: This technique provides an easy, efficient loss-of-function manipulation for developmental and gene regulatory studies in these important non-bilaterian animals