5,914 research outputs found
Case report. A rare case of giant basal cell carcinoma and malignant melanoma
The presence of two several skin lesions in the same patient is a rare occurrence in dermatological findings. The associations of malignant melanoma (MM) and giant basal cell carcinoma (BCC) within the same patient have only been described in few cases in the literature.1,6 Is there a common genetic origin? However, until now the pathogenesis of collision tumors existing of MM and BCC remains unclear. We, therefore, report a case of association of MM and BCC in the same patient
A rare case of leiomyoma of the bladder
Bladder leiomyoma is a benign tumour of the bladder and constitute <0.5% of all bladder tumors. We report a clinical case of a 51‑year‑old female who presented with with symptomatic bladder leiomyoma. An ultrasound examination showed well-defined bladder leiomyoma in the right posterior bladder wall, which was excised through a transurethral resection. The pathologic diagnosis was bladder leiomyoma
Open and / or laparoscopic surgical treatment of liver hydatic cysts
Hydatid disease is a severe parasitic disease with a widely ranging distribution. In the human being the liver is the most frequent organ affected. 1 The treatment should be individualized to the morphology, size, number and location of the cysts, that is why a variety of surgical operations have been advocated from complete resection like total pericystectomy or partial hepatectomy to laparoscopy to a minimally invasive procedures like percutaneous aspiration of cysts to conservative drug therapy. 3-4 This study compares laparoscopic versus open management of the hydatid cyst of liver the surgical approach to liver echinococcosis is still a controversial issue and shows our results of surgical treatment of liver hydatid cysts during a 3-years period
Comment on "Research on values of GDF-15 level in the diagnosis of primary liver cancer and evaluation of chemotherapeutic effect"
Comment on research on values of GDF-15 level in the diagnosis of primary liver cancer and evaluation of chemotherapeutic effec
Evaluating the expression of urokinase and tissue leukocyte being in benign and malignant breast disease
Introduction: Our objectives is to show that the expression of uPA leukocyte could be considered, in the future, as a marker of
the expression of uPA in the malignant tissue and therefore a potential indicator of prognosis.
Methods: We examined the expression of uPa in leukocytes and tissues of three groups of women: with breast cancer; with
benign breast lesion and healthy women (control group). We used RT Real Time PCR assay. The expression of urokinase is
significantly higher in malignant breast lumps compared to benign lesions. However, in women with carcinoma of the breast,
malignant tissue expresses higher amounts of uPA than the healthy counterpart. There are no statistically significant differences in
the expression of uPA, between tissues taken from women with benign lesions. The lymphocytes taken from healthy volunteers
show a level of expression of uPA significantly lower than the other tested samples Lymphocytes extracted from cancer patients
express higher amounts of uPA compared to lymphocytes belonging to women with benign breast lesions. The expression of uPA
was compared with the clinical and biological parameters commonly used in clinical practice for the definition of the prognosis.
The only exception found, concerns those tumors characterized by the simultaneous negativity for estrogen receptors,
progesterone and HER2 (state of triple negative), in which the expression of uPA is very high.
Results and conclusions: Our data show that uPA expressed by leukocytes of each individual patient is the mirror image of the
one expressed by malignant nodular uPA.Introduction: Our objectives is to show that the expression of uPA leukocyte could be considered, in the future, as a marker of
the expression of uPA in the malignant tissue and therefore a potential indicator of prognosis.
Methods: We examined the expression of uPa in leukocytes and tissues of three groups of women: with breast cancer; with
benign breast lesion and healthy women (control group). We used RT Real Time PCR assay. The expression of urokinase is
significantly higher in malignant breast lumps compared to benign lesions. However, in women with carcinoma of the breast,
malignant tissue expresses higher amounts of uPA than the healthy counterpart. There are no statistically significant differences in
the expression of uPA, between tissues taken from women with benign lesions. The lymphocytes taken from healthy volunteers
show a level of expression of uPA significantly lower than the other tested samples Lymphocytes extracted from cancer patients
express higher amounts of uPA compared to lymphocytes belonging to women with benign breast lesions. The expression of uPA
was compared with the clinical and biological parameters commonly used in clinical practice for the definition of the prognosis.
The only exception found, concerns those tumors characterized by the simultaneous negativity for estrogen receptors,
progesterone and HER2 (state of triple negative), in which the expression of uPA is very high.
Results and conclusions: Our data show that uPA expressed by leukocytes of each individual patient is the mirror image of the
one expressed by malignant nodular uPA
A case of primary Hodgkin's lymphoma of the parotid gland. Case report and differentian diagnosis from Kuttner's Syndrom
Abstract
We report a rare case of primary Hodgkin’s lymphoma (HL) of the submandibular
gland, with initially diagnosis of Kuttner’s Syndrom. A 48 years old man was referred to our hospital foe evaluation
of a submandibular mass. Although the initial Fine Needle Aspiration and subsequent cytology was highly suggestive for a cronic sialadenitis with lymphoid cells.
After surgical gland removal we obtained a definitive diagnosis of Hodgkin’s lymphoma in
submandibular gland a seat where the most common lymphoma tipe is B
Which is the most accurate diagnostic procedure in Tamoxifen treated breast cancer patients
Purpose: The aim of this study was to evaluate the diagnostic accuracy of bi-dimensional (2D) and three-dimensional (3D) transvaginal ultrasound (TVUS), hysterosonography (HSSG) and hysteroscopy in the detection of endometrial pathology in women treated with tamoxifen (TMX) for breast cancer.
Methods: Forty-two patients, affected by breast cancer under treatment with TMX, underwent 2D-3D TVUS, HSSG and hysteroscopy completed by biopsy, after abnormal findings following a routine 2D TVUS examination.
Results: 3D-TVUS was more accurate than 2D-TVUS in the detection of atrophic endometrium confirmed by biopsy and in the detection of endometrial polyps.
HSSG and hysteroscopy detected atrophic endometrium and endometrial polyps significantly better than ultrasound scan. Endometrial carcinoma was detected in two cases, and in both HSSG and hysteroscopy were 100% diagnostic.
Conclusion: In TMX treated breast cancer patients, HSSG and hysteroscopy provide more accurate diagnosis than 2D-3D ultrasound in the detection of treatment related endometrial lesions
Stochastic background of gravitational waves "tuned" by gravity
The cosmological background of gravitational waves can be tuned by Extended
Theories of Gravity. In particular, it can be shown that assuming a generic
function of the Ricci scalar gives a parametric approach to control
the evolution and the production mechanism of gravitational waves in the early
Universe.Comment: 5 pages, to appear in the Proceedings of the 3rd Stueckelberg
Workshop, July 2008, Pescara - Ital
The FORS1 catalogue of stellar magnetic field measurements
The FORS1 instrument on the ESO Very Large Telescope was used to obtain
low-resolution circular polarised spectra of nearly a thousand different stars,
with the aim of measuring their mean longitudinal magnetic fields. A catalogue
of FORS1 magnetic measurements would provide a valuable resource with which to
better understand the strengths and limitations of this instrument and of
similar low-dispersion, Cassegrain spectropolarimeters. However, FORS1 data
reduction has been carried out by a number of different groups using a variety
of reduction and analysis techniques. Our understanding of the instrument and
our data reduction techniques have both improved over time. A full re-analysis
of FORS1 archive data using a consistent and fully documented algorithm would
optimise the accuracy and usefulness of a catalogue of field measurements.
Based on the ESO FORS pipeline, we have developed a semi-automatic procedure
for magnetic field determinations, which includes self-consistent checks for
field detection reliability. We have applied our procedure to the full content
of circular spectropolarimetric measurements of the FORS1 archive. We have
produced a catalogue of spectro-polarimetric observations and magnetic field
measurements for about 1400 observations of about 850 different objects. The
spectral type of each object has been accurately classified. We have also been
able to test different methods for data reduction is a systematic way. The
resulting catalogue has been used to produce an estimator for an upper limit to
the uncertainty in a field strength measurement of an early type star as a
function of the signal-to-noise ratio of the observation. While FORS1 is not
necessarily an optimal instrument for the discovery of weak magnetic fields, it
is very useful for the systematic study of larger fields, such as those found
in Ap/Bp stars and in white dwarfs.Comment: Accepted for publication by A&
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