Relationship Between Glycaemic Control And Hypertension In Nigerian Type II Diabetic Patients Attending The Medical Outpatient Clinics, U.I.T.H. Ilorin

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Cardio-metabolic risk factors among young infertile women: a systematic review and meta-analysis

BACKGROUND:There is currently no concise systematic review or meta-analysis addressing cardio-metabolic risk factors in women experiencing infertility. OBJECTIVES:To determine whether infertile women have higher levels of cardiovascular risk factors compared to fertile women. SEARCH STRATEGY:We performed a systematic literature search using Pubmed, EMBASE and CINAHL, Scopus and additional manual and bibliographic searches for relevant articles (end search date of 6th November 2019). SELECTION CRITERIA:We selected studies that compared cardio-metabolic risk factors between fertile and infertile women of reproductive age. DATA COLLECTION AND ANALYSIS:At least two authors independently screened potentially eligible studies. MAIN RESULTS:There was an increased presence of several cardio-metabolic risk factors in infertile women compared to fertile women. Infertile women had statistically significant higher BMI, increased TC, LDL-C, and TG compared to fertile women. Fasting glucose, fasting insulin, HOMA-IR and MAP were not found to be different between fertile and infertile women. A subgroup analysis revealed that TC, HDL-C, fasting glucose and fasting insulin were increased only in women with polycystic ovarian syndrome compared to fertile women, while BMI, TG and LDL-C were statistically significantly increased in women with any indication of infertility compared to fertile women. CONCLUSIONS:Infertile women have a higher level of cardio-metabolic risk factors compared to fertile women. This finding has clinical implications for infertile women in general, and those attempting to conceive through medically assisted reproduction.C.L. Mulder, Z.S. Lassi, J.A. Grieger, A Ali, T Jankovic‐Karasoulos, C.T. Roberts, P.H. Andraweer