Low-grade Myofibroblastic Sarcoma at the Base of the Tongue

Low-grade myofibroblastic sarcoma (LGMS) represents a distinct atypical myofibroblastic tumor that occurs at several sites, primarily within the head and neck regions. A painless, enlarged mass is the most common clinical presentation, but a definitive diagnosis requires both histopathological and immunohistochemical analyses. Histologically, LGMS commonly presents as a cellular lesion composed of spindle-shaped tumor cells arranged primarily in fascicles with a diffusely infiltrative pattern. Immunohistochemically, LGMS shows positive staining for at least one myogenic marker, such as desmin or muscle actin. Here we report a case of LGMS in the base of the tongue. Our case showed positive immunostaining for desmin and vimentin, and was thus diagnosed as LGMS. The patient received surgery, but no chemotherapy or radiotherapy, and was completely without evidence of the disease 38 months after the surgery

Cervical Sympathetic Chain Schwannomas

Surgery for cervical sympathetic chain schwannomas may result in postoperative Horner\u27s syndrome. Thus, appropriate informed consent and adequate surgical experience are required to prevent any decrease in patients\u27 quality of life (QOL) following such surgery. Here we report three cases of cervical sympathetic chain schwannomas, focusing on diagnosis and postoperative neuroparalysis. A schwannoma is suspected on pre-operative imaging when the common carotid artery (internal and external carotid artery) and internal jugular vein are located in front of or alongside the tumor, and cases in which the artery and vein are not separated are considered to be of sympathetic nerve origin. Since the origin nerve comes from the back anatomically, great care is needed during surgery. None of the patients in this study had symptoms of nerve paralysis postoperatively