2 research outputs found

    ROLE OF OLIVE OIL IN CANCER PREVENTION

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    Cancer is the second leading cause of death in the United States. From this fact showshow ferociously the disease if not treated well. The emergence of this disease is causedby various factors, but often caused by damage to the structure of DNA and othermolecular structures by a reactive oxygen species (ROS). Early prevention that can beimplemented, is to improve the lifestyle and diet that contains a substance that canprotect our body cells from damage caused by ROS. These molecules calledantioxidants. Therefore, antioxidants are often called reducing agents (thiol orpolyphenols). Olive oil is the one of the exogenous antioxidants have many benefitsespecially polyphenols that have chemo preventive effects on several types of cancer,and can inhibit the process of carcinogenesis by several mechanisms such as inhibitionof DNA synthesis in the process, reducing the production of ROS, regulate cell cycle,regulate proliferation and survival mechanisms of cells.<br /

    THE ROLE OF ESTROGEN IN WOMEN WITH ANDROGENETIC ALOPECIA

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    Normal 0 false false false EN-US X-NONE X-NONE Hair loss may accured in both male and female population. Hair loss usually accured in Telogenic phase, meanwhile in Anagenic phase hair loss due to chemotherapy or radiation. Female pattern hair loss (FPHL) is regarded as hair fall type which is accured in women in common and known as female androgenetic alopecia. Almost 40%, 50 years old female shown hair fall sign, which is developed progressive fibrosing alopecia of central scalp, especially in frontal and parietal area. There are two common treatment for Female pattern Hair Loss are Minoxidil for topical use, and Fenesteride by oral. However, it has long been known that estrogens also profoundly alter hair follicle growth and cycling by binding to locally expressed high-affinity estrogen receptors (ERs), in turn increase anagenic phase and represed telogenic phase. /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} <![endif]--
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