16 research outputs found
Validity of modified early warning, Glasgow Blatchford, and pre-endoscopic Rockall scores in predicting prognosis of patients presenting to emergency department with upper gastrointestinal bleeding
- Author
- AC Meltzer
- AJ Stanley
- AJ Stanley
- Ataman Köse
- CH Wang
- CP Subbe
- Cüneyt Ayrık
- D Dicu
- DW Cheng
- E Göksu
- Engin Deniz Arslan
- Enver Üçbilek
- FT Farooq
- H Ali
- I Khamaysi
- İbrahim Çevik
- IC Chen
- J Ludikhuize
- JK Lim
- JN Fullerton
- JR Stephens
- L Camellini
- MT Blanche
- O Blatchford
- Orhan Sezgin
- R Srirajaskanthan
- RV Bryant
- S Chandra
- Semra Erdoğan
- Seyran Bozkurt
- SH Pang
- T Masaoka
- TA Rockall
- TA Rockall
- Ö Köksal
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Molecular alterations as target for therapy in metastatic osteosarcoma: a review of literature
- Author
- A Abdeen
- A Briccoli
- A Jeanes
- AJ Chou
- AJ Minn
- B. J. van Royen
- BH Hoang
- C Khanna
- C Khanna
- C Laverdiere
- C Yang
- C Zucchini
- CM Diaz-Montero
- CY Huang
- D Barkan
- D Hanahan
- DG Fan
- DP Hughes
- DP Hughes
- E Favaro
- E Pradelli
- EA Kolb
- EA Kolb
- EA Lafleur
- EA Lafleur
- EI Hauben
- EM Rubin
- F deNigris
- F Engin
- FH Igney
- G Bacci
- G. J. L. Kaspers
- HC Reinhardt
- HS Kim
- IC Wang
- J Fuchs
- J Whelan
- J. PosthumaDeBoer
- K Krishnan
- K Ryu
- K Scotlandi
- KA Nyberg
- L Kager
- L Mirabello
- L Ren
- LC Kim
- LL Worth
- M Kansara
- M Kansara
- M Kaya
- M Pasello
- M Tanaka
- M. A. Witlox
- MT Harting
- N Almog
- N Gordon
- NI Rodriguez
- P Anderson
- P Hingorani
- P Zhang
- PC Leow
- PJ Mansky
- PJ Messerschmitt
- PM Murphy
- PS Steeg
- R Gorlick
- RG Syljuasen
- RN Kaplan
- RO Hynes
- S Schuetze
- SA Eccles
- SJ Strauss
- SS Bielack
- SS Bielack
- SY Kim
- T Kashima
- T Kawabe
- VO Lewis
- X Duan
- X Liu
- X Wan
- XW Yuan
- Y Cai
- Y Guo
- Y Guo
- Y Nakamura
- Y Pignochino
- Publication venue
- Springer Netherlands
- Publication date
- 01/01/2011
- Field of study
Treating metastatic osteosarcoma (OS) remains a challenge in oncology. Current treatment strategies target the primary tumour rather than metastases and have a limited efficacy in the treatment of metastatic disease. Metastatic cells have specific features that render them less sensitive to therapy and targeting these features might enhance the efficacy of current treatment. A detailed study of the biological characteristics and behaviour of metastatic OS cells may provide a rational basis for innovative treatment strategies. The aim of this review is to give an overview of the biological changes in metastatic OS cells and the preclinical and clinical efforts targeting the different steps in OS metastases and how these contribute to designing a metastasis directed treatment for OS
Iron Behaving Badly: Inappropriate Iron Chelation as a Major Contributor to the Aetiology of Vascular and Other Progressive Inflammatory and Degenerative Diseases
- Author
- A Abbott
- A Abou-Raya
- A Aljandali
- A Ambesi-Impiombato
- A Aydin
- A Balcerczyk
- A Besarab
- A Brzezinski
- A Campbell
- A Carrillo-Vico
- A Cavalli
- A Chattopadhyay
- A Chattopadhyay
- A Cherubini
- A Dey
- A Doms
- A Donovan
- A Donovan
- A Dávalos
- A Gaeta
- A Garny
- A Gnjec
- A Gomes
- A Gopalakrishnan
- A Hald
- A Henney
- A Hirayama
- A Hoffmann
- A Huber
- A Hugman
- A Iannetti
- A Ide-Ektessabi
- A Jacobs
- A Jeyabalan
- A Kahvejian
- A Karrar
- A Kasztler
- A Kibel
- A Kocyigit
- A Kotha
- A Kumral
- A Lass
- A Lecube
- A Lewén
- A Lotery
- A Maggio
- A Malek
- A Malik
- A Mantovani
- A Matsuzawa
- A Mitra
- A Monge
- A Murakami
- A Murakami
- A Murakami
- A Murakami
- A Mutti
- A Nijnik
- A Nunomura
- A Nunomura
- A Patt
- A Persson
- A Pietrangelo
- A Piga
- A Pirat
- A Post
- A Pradhan
- A Protti
- A Rattner
- A Ravati
- A Rehman
- A Reynolds
- A Richmond
- A Roetto
- A Roetto
- A Rostom
- A Rumbold
- A Russo
- A Rötig
- A Saltelli
- A Saltelli
- A Sandek
- A Sassano
- A Scalbert
- A Scalbert
- A Scalbert
- A Sica
- A Smahi
- A Sola
- A Stintzi
- A Szewczyk
- A Taguchi
- A Tedgui
- A Terman
- A Terman
- A Terman
- A Undas
- A Virdis
- A Wagner
- A Wagner
- A Wagner
- A Wagner
- A Wojas-Pelc
- A Wong
- A Xu
- A Yoritaka
- A Yoshimura
- A-L Barabási
- AA Andreadis
- AA Borisy
- AA Farooqui
- AA Qutub
- AA Qutub
- AA Vlessis
- AB Nathens
- AB Parsons
- AB Parsons
- AB Thompson
- AB Thomson
- AC Bayne
- AC Bharti
- AC Cave
- AC Mello Filho
- AD d'Hardemare
- AD de Silva
- Ad hoc committee on systemic lupus erythematosus response criteria for fatigue
- ADL van der
- AE Aust
- AE Baue
- AE Finefrock
- AE Heazell
- AE Heazell
- AE Kartikasari
- AEC Ihekwaba
- AEC Ihekwaba
- AF Tramontano
- AH Berg
- AH Koeppen
- AH Koeppen
- AH Tong
- AI Bush
- AI Bush
- AI Bush
- AI Bush
- AI Faden
- AJ Ghio
- AJ Ghio
- AJ Ghio
- AJ Hulbert
- AJ Kowaltowski
- AJ Lusis
- AJ Matthews
- AJ Reyes
- AJ van Oostrom
- AJ Watson
- AJ White
- AJ Williams
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- AL Beal
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- AL Hopkins
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- AM Choi
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- AM Samuni
- AM Snyder
- AN Crowson
- AN Tabah
- AP Bolger
- AP Breen
- AP Liappis
- AR Kallianpur
- AR Kallianpur
- AR Martin
- AR Ness
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- AS Baldwin Jr
- AS Binbrek
- AS Kaprelyants
- AS Wierzbicki
- AT McKie
- AV Lebedev
- AV Perkins
- AV Rao
- AW Maresso
- AY Andreyev
- AY Sun
- B Chakravarti
- B Chance
- B Cronin
- B de Valk
- B De Vries
- B Desoize
- B Drayer
- B Faller
- B Goodell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Huppertz
- B Jayawardhana
- B Kwak
- B Lachili
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- B Pradines
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- B Schiessl
- B Shipley
- B Skibska
- B Sturm
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- B Wang
- B Wolff
- B Wolozin
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- B Xu
- B Zhang
- B Zhou
- BA Maddux
- BA Molitoris
- BB Aggarwal
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- BS Chen
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- BØ Palsson
- C Arnaud
- C Beaumont
- C Behl
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- C Bolin
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- C Brooksbank
- C Bubici
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- C Camaschella
- C Camaschella
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- C Cavdar
- C Chen
- C Delaby
- C Demougeot
- C Finch
- C Fleury
- C García-Ruiz
- C Gasche
- C Gasche
- C Gerhäuser
- C Goble
- C Henry
- C Herce-Pagliai
- C Herder
- C Hershko
- C Hershko
- C Hershko
- C Hershko
- C Jacob
- C Kenyon
- C Knox
- C Kretz-Remy
- C Kunsch
- C Köhle
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- C Li
- C Lu
- C Manach
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- CJA Doelman
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- CY Wang
- CY Wu
- D Agnello
- D Barisani
- D Ben Shachar
- D Berg
- D Berg
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- D Closa
- D De Roure
- D DeFaria Yeh
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- D Galaris
- D Galter
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- D HaMai
- D Hamerman
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- D Hristovski
- D Hull
- D Hull
- D Imbert
- D Johnson
- D Kaur
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- D Lapenna
- D Law
- D Meyer
- D Mozaffarian
- D Noble
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- D Ponraj
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- D Salvemini
- D Tapscott
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- D Trinder
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- D Weininger
- D Yoon
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- VB O'Donnell
- VD Longo
- VE O'Collins
- VE Steele
- VH Haase
- VL Kinnula
- VL Kinnula
- VM Campese
- VM Victor
- VM Victor
- VN Anisimov
- VR Gordeuk
- VR Gordeuk
- VR Taqueti
- W Aerbajinai
- W Breuer
- W Craelius
- W Davis Jr
- W Dichtl
- W Dröge
- W Dröge
- W Hu
- W Kalt
- W Kong
- W Li
- W Ma
- W Mair
- W Makropoulos
- W Ondo
- W Tungwiwat
- WA Cass
- WB Dunn
- WB Ershler
- WB Kannel
- WI Leong
- WJ Jo
- WK Adkins
- WL Neeley
- WM Campana
- WR Farwell
- WR Markesbery
- WR Markesbery
- WS Jeong
- WS Yang
- WW Huber
- WW Wong
- WY Ong
- X Chen
- X Chen
- X He
- X Huang
- X Huang
- X Huang
- X Li
- X Zhang
- X Zhu
- X Zhu
- XD Huang
- XJ Li
- XM Yuan
- XM Yuan
- XP Huang
- Y Almog
- Y Avramovich-Tirosh
- Y Bao
- Y Bdolah
- Y Chen
- Y Christen
- Y Curin
- Y Deugnier
- Y Deugnier
- Y Engin-Üstün
- Y Ge
- Y Gilgun-Sherki
- Y Haruna
- Y Honda
- Y Hua
- Y Ikeda
- Y Jiao
- Y Jung
- Y Ke
- Y Ke
- Y Kohgo
- Y Kohgo
- Y Levites
- Y Li
- Y Okatani
- Y Okatani
- Y Sai
- Y Sai
- Y Sun
- Y Takada
- Y Wang
- Y Wang
- Y Wei
- Y Wei
- Y Wu
- Y Wu
- Y Zhang
- Y Zhang
- Y Zhang
- Y Zhao
- Y Zheng
- YE Henrotin
- YF Chu
- YH Lee
- YH Suh
- YH Wei
- YJ Surh
- YJ Surh
- YJ Surh
- YK Wu
- YM Kim
- YS Keum
- YS Sohn
- YX Ma
- YZ Fang
- Z Cai
- Z Cai
- Z Cheng
- Z Pei
- Z Serdar
- Z Tong
- Z Tong
- Z Yu
- Z Zhang
- ZD Liu
- ZD Liu
- ZE Karanjawala
- ZE Suntres
- ZI Cabantchik
- ZZ Chong
- ZZ Chong
- Publication venue
- Publication date
- 09/08/2008
- Field of study
The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular "reactive oxygen species" (ROSs)
can exhibit a number of biological effects, they are not of themselves
excessively reactive and thus they are not especially damaging at physiological
concentrations. However, their reactions with poorly liganded iron species can
lead to the catalytic production of the very reactive and dangerous hydroxyl
radical, which is exceptionally damaging, and a major cause of chronic
inflammation. We review the considerable and wide-ranging evidence for the
involvement of this combination of (su)peroxide and poorly liganded iron in a
large number of physiological and indeed pathological processes and
inflammatory disorders, especially those involving the progressive degradation
of cellular and organismal performance. These diseases share a great many
similarities and thus might be considered to have a common cause (i.e.
iron-catalysed free radical and especially hydroxyl radical generation). The
studies reviewed include those focused on a series of cardiovascular, metabolic
and neurological diseases, where iron can be found at the sites of plaques and
lesions, as well as studies showing the significance of iron to aging and
longevity. The effective chelation of iron by natural or synthetic ligands is
thus of major physiological (and potentially therapeutic) importance. As
systems properties, we need to recognise that physiological observables have
multiple molecular causes, and studying them in isolation leads to inconsistent
patterns of apparent causality when it is the simultaneous combination of
multiple factors that is responsible. This explains, for instance, the
decidedly mixed effects of antioxidants that have been observed, etc...Comment: 159 pages, including 9 Figs and 2184 reference
Prediction of blasting-induced fragmentation in Meydook copper mine using empirical, statistical, and mutual information models
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- 'Springer Science and Business Media LLC'
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- Field of study
A three-dimensional forward dynamic model of the golf swing optimized for ball carry distance
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- A Cochran
- A Engin
- A Schultz
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- Daniel Balzerson
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- E Henrikson
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- SJ MacKenzie
- SJ Quintavalla
- SM Nesbit
- T Iwatsubo
- WM Pickering
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- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Solving the two-stage hybrid flow shop scheduling problem based on mutant firefly algorithm
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- A Allahverdi
- A Allahverdi
- Beibei Fan
- BMT Lin
- C Kahraman
- CJ Liao
- E Teymourian
- E Torabzadeh
- FD Chou
- GQ Huang
- H Xuan
- I Ribas
- IC Lin
- J Yang
- JIR Molano
- JND Gupta
- JQ Li
- L Wang
- O Engin
- P Fattahi
- Q Zhang
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- R Ruizab
- RJ Paul
- RY Zhong
- S Wang
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- T Ning
- T Nishi
- TP Chung
- W Bożejko
- Wenwei Yang
- X Li
- X Liang
- XS Yang
- Y Tian
- Z Hongsheng
- Zaifang Zhang
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- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Magnesium’s role in bone fractures of overweight children and adolescents
- Author
- A Engin
- A Goulding
- A Goulding
- A Goulding
- A Mazur
- AD Hirschfelder
- AL Boskey
- AL Tranquilli
- AO Gobato
- B Herngren
- C Malpuech-Brugère
- C-H Chang
- CN Lumeng
- DL Skaggs
- F Guerrero-Romero
- F-Y Li
- HY Kim
- I Nikolic
- IC Backstrom
- J Kessler
- JHF De Baaij
- JN Farr
- K He
- KL Tucker
- KM Ryder
- L Karim
- L Lisenda
- M Ordak
- MG Huerta
- MM Belluci
- N Ouchi
- NCD Risk Factor Collaboration (NCD-RisC)
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- VA D’Hondt
- VL Bland
- W ELDerawi
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- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Increasing fasting glucose and fasting insulin associated with elevated bone mineral density—evidence from cross-sectional and MR studies
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- A Saller
- AB Engin
- AC Kaliora
- C Conte
- CA Emdin
- D Shin
- DE Bonds
- DR Matthews
- F Javed
- F Sassi
- GA Faulhaber
- GD Smith
- GM Reaven
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- MB Greenblatt
- N Napoli
- NB Kasim
- NE Lane
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- P Vestergaard
- PN Sambrook
- R Sealand
- RA Scott
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- RD Wasnich
- S Adami
- S Arikan
- S Botolin
- S Costantini
- S Ishii
- S Yakar
- TL Patrocinio-Silva
- V Didelez
- V Lundback
- VM Tagi
- VV Shanbhogue
- W Yan
- WD Leslie
- Y Kasukawa
- Y Sheu
- Y Zhang
- YC Klimentidis
- Z Hu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Rare and Secondary Tumors of the Kidney and Renal Pseudotumors
- Author
- A Mejean
- A Orsola
- AB Gelb
- AJ Davidson
- BA Urban
- BJ Wagner
- C Roy
- CA Hanau
- CJ Davis Jr
- D Chao
- DJ Choi
- DS Hartman
- ER Carazo
- FN Tessler
- G Engin
- GM Israel
- GM Israel
- H Isobe
- H Takao
- HL Abrams
- I Hamilton
- I Pedrosa
- IC Chiang
- IK Walsh
- J Beaudoin
- JE Madewell
- JK Hopkins
- JR Srigley
- K Enomoto
- K Idrissi-Serhrouchni
- KD Fairbanks
- KE Warren
- L Garel
- LD Narla
- LH Lowe
- M Kumar
- MS Gibson
- MT Heller
- NM Blitman
- NR Dunnick
- PJ Pickhardt
- PL Choyke
- R Krishnamurthy
- RE Bechtold
- RE Bechtold
- RJ Zagoria
- RJ Zagoria
- RK Zeman
- RR Pascal
- S Bhatt
- S Mazziotti
- S Sheth
- S Störkel
- SE Rha
- SK Yoon
- SR Prasad
- T Koyama
- TA Lalani
- TR Johnson
- VA Leitao
- VR Surabhi
- VS Katabathina
- WK Volders
- WS Hayes
- Z Melegh
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A Distribution-Free Description of Fragmentation by Blasting Based on Dimensional Analysis
- Author
- A Daehnke
- A Hafsaoui
- A Scott
- A Tosun
- AA Griffith
- AK Raina
- AK Raina
- AM Gaudin
- AO Gates
- AT Spathis
- AT Spathis
- AT Spathis
- AT Spathis
- B Ma
- CH Scholz
- CK McKenzie
- CM Lownds
- CVB Cunningham
- CVB Cunningham
- D Johansson
- D Price
- D Thornton
- DK Roberts
- E Hoek
- E Sellers
- EA Eissa
- EA Koshelev
- EP Dulaney
- F Faramarzi
- F Ouchterlony
- F Ouchterlony
- F Ouchterlony
- F Ouchterlony
- F Ouchterlony
- F Ouchterlony
- F Ouchterlony
- F Ouchterlony
- F Ouchterlony
- F Vanbrabant
- Finn Ouchterlony
- G Bekkers
- GAF Seber
- GE LeJuge
- GV Borquez
- I Onederra
- IC Engin
- J Boudet
- J Cáceres Saavedra
- JA Sanchidrián
- JA Sanchidrián
- JA Sanchidrián
- JC Jaeger
- JM Adebola
- José A. Sanchidrián
- KA Holsapple
- KR Housen
- LB Freund
- LN Marchenko
- M Jahani
- MA Morin
- MS Stagg
- MS Stagg
- MS Stagg
- P Katsabanis
- P Rosin
- P Schimek
- PA Lilly
- PA Lilly
- PA Persson
- PD Katsabanis
- PD Katsabanis
- PD Katsabanis
- PK Singh
- Q Liu
- R Ivanova
- RE Otterness
- RR Rollins
- S Gheibie
- S Gheibie
- S Kou
- S Rodger
- S Strelec
- SH Chung
- SR Winzer
- SS Kanchibotla
- SS Mitrovic
- T Kojovic
- U Langefors
- VM Kuznetsov
- W Weibull
- WL Fourney
- Y Hirosaki
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study