Influence of individual behavioral risk factors (smoking, drinking) on mortality in the population cohort of adult people 20—59 years old in Tomsk (17-year prospective study)

In 17-year prospective cohort study, we analyzed the influence of smoking and drinking on the formation of cardiovascular and general mortality of adult people in Tomsk. The cohort included 1 546 people (630 men and 916 women) aged 20—59 years. It has been found that due to smoking the 17-year risk of death by any cause increases 2.4 times among men and 2.7 times among women. The increase in the frequency of drinking in the male population increase the risk of death by any cause 1.6 times (for men drinking once a month or more rarely), 2.4 times (for men drinking once a week and more rarely, but more often than once a month), and 3.8 times (for men drinking more often than once a week). The risk of death by cardiovascular diseases increases 1.7, 2.9, and 4.9 times, respectively

Body mass, marital status, and number of children in the family

Aim. To study the effects of social factors (marital status, the number of children born and raised in the family) on the incidence of body weight (BW) increase. Material and methods. The 15-year follow-up focussed on BW dynamics in men and women, in regard to the changes in their martial status. At baseline, all participants were married (n=845; 327 men and 518 women). To evaluate the effects of the children’s number on increased BW incidence, 238 women aged 40—59 years and having at least one child before the baseline, were examined (≥ 2 children in 163 women, 1 child in 75 women). Increased BW was registered if body mass index (BMI) was 25 kg/m2 or higher. Results. In widowed participants, the incidence of BW increase was lower (1,9 %) than in those married (10,5 %; p<0,01) or divorced (21,4 %; p<0,01). In widowed women, the normalisation of initially increased BW was registered more often (13,5 %), compared to their still married peers (4,3 %; p<0,05). In those still married, BMI increased from 26,95±0,09 to 27,91±0,09 kg/m2 (p<0,001), while in those widowed, it decreased from 29,92±0,24 to 29,34±0,24 kg/m2 (p<0,05). In women with 2 or more children, the incidence of BW increase was higher (85,3 %) than in women with only one child (73,3 %; p<0,05). Conclusion. The change in marital status could affect BW dynamics. Spouse death is an important cause of BW reduction. In women with 2 or more children, increased BW was more common than in women with only one child

Natural dynamics of hypertriglyceridemia: incidence, regression, mortality from cardiovascular diseases and all causes (according to the results of a 17-years prospective study)

In 17-year nested prospective study, the natural dynamics of hypertriglyceridemia (HTG) (development of new cases, regress), cardiovascular mortality and other mortality of patients with HTG have been examined. The nest included 630 men and 916 women from 20 to 59 years old. The HTG incident in the nest was 8.24 cases per 1000 people*years of observation. Among people 20—29 years old, new HTG cases were observed more often in men, while in the age interval of 30—59 years, new cases were more often observed in women. For the period of observation, the HTG occurrence increased 1.6 times in men and 2.1 times in women. HTG is characterized by the low course stability, and the regress level is independent of sex. Among men and women, Among men and women with HTG, brain stroke and cardiovascular mortality is higher than that among people with the normal triglyceride (TG) level. The TG level did not affect the total men mortality

Correlation of spouses’ body weight (results of a 15-year prospective study)

Aim. To study the cross-sectional prevalence of overweight (OW) in men and women, in regard to their spouses’ body weight (BW), as well as to assess the BW dynamics in participants and their spouses over 15 years of the prospective follow-up. Material and methods. In the screening study, body mass index (BMI) was assessed in 425 married couples. The repeat assessment, performed 15 years later, included 232 couples who were still married. OW was diagnosed in subjects with BMI ≥25 kg/m2. Results. In the wives of OW men, OW prevalence was higher (76,2%) than in the spouses of non-OW men (61,3%; p<0,001). In the husbands of OW women, OW prevalence was also higher (61,3%) than in the spouses of non-OW women (43,8%; p<0,001). In the prospective study, the participants with no OW at baseline, whose spouses developed OW, the incidence of OW was significantly higher (60,9%) than in participants whose spouses remained non-OW (16,4%; p<0,001), or in participants whose spouses remained OW (31,7%; p<0,05). Among men and women with OW at baseline, whose spouses reduced their BW and became non-OW, BW normalization was more frequent (32,0%) than in the participants whose spouses either remained OW (9,1%; p<0,001), or remained nonOW (3,4%; p<0,001), or increased BW and became OW (6,9%; p<0,05). Conclusion. BW dynamics in spouses was characterized by parallel increases or decreases, due to shared social and intra-familial factors