Global characteristics of nucleus-nucleus collisions in an ultrarelativistic domain

The global observable distributions of nucleus-nucleus collisions at a high energy are studied. It is shown that these distributions are sensitive to interaction dynamics and can be used to investigate the evolution of dense nuclear matter. On the LHC energy scale ( square root s/sub NN/=5 TeV in the heavy-ion mode), a central bump over the pseudorapidity plateau in jet quenc

Crewing of Sea Vessels Taking into Account Project Risks and Technical Condition of Ship Equipment

Motivation: One of the main concepts in project management is the concept of “team†in the project, and in project management - the human resources management of the project, which includes the processes of planning, forming and creating a team, its development and support activities, transformation or disbandment of the team. Despite the great attention paid to the formation of project management teams, existing studies do not fully highlight the specifics and features of crew operations. Criteria for the quantitative optimization of the ship's crew should be consistent with the main objectives of the project.Novelty: The research paper proposes an approach that allows optimizing the quantitative composition of the crew of a ship by more accurately assessing the level of project risks and costs associated with the maintenance of ship equipment. The practical application of this approach will optimize the quantitative composition of the ship's crew, which will both satisfy the needs of managing the technical equipment and minimize the risks and costs of the shipowner.Methodology and Methods: Risk management tools were used to achieve the objective and test the hypotheses suggested in the research, namely: methodology for estimating the net present value of the project; the method of estimating internal rate of return for the project; the method of estimating the return on investment in the project; the method of estimation for the period of return on investment costs in the project; the method of estimating the discounted payback period for the project, as well as the tools of simulation modelling (Monte Carlo simulation method). The method of identification and grouping in the process of classification of project risks in the sphere of marine transportation, methods of systematization, grouping and logical generalization were also applied for systematization of information, drawing conclusions and making scientific suggestions in the research.Policy Considerations: Shipping plays an important role in the trade and tourism industry; human factor is the most important aspect that determines the efficiency of shipping development; maintaining of technical and technological processes of the ship puts certain requirements to the quantitative and qualitative composition of the team, deviation from which leads to the occurrence of certain risk events; formation of an effective model of ship's crew manning is the main link in ensuring effective shipping project management

Information support system for regional human resource development

In paper suggest a concept of information support system for human resource management at a regional level. We identify the main factors that affect quantitative and qualitative characteristics of regional human resource, including educational system, demographic and migration processes, and present a concept of the Program for its development. As a tool for information support of the Program propose a distributed information system with interfaces for various groups of users: regional administration, population and organization

Using Shewhart charts to monitor quality characteristics of preventive vaccines for tuberculosis

Scientific relevance. The quality of medicinal products, particularly vaccines, is contingent on the stability of the manufacturing process at all stages, which can be evaluated using Shewhart charts for data obtained by monitoring the quality attributes of interest.Aim. This study evaluated the stability of the quality and manufacturing processes of the BCG and BCG-M tuberculosis vaccines using Shewhart charts.Materials and methods. This study focused on samples of the BCG tuberculosis vaccine and the BCG-M tuberculosis vaccine, a less reactogenic alternative for primary immunisation. Both vaccines were released to the market in 2019–2022. The quality of samples was assessed for stability based on their potency and total bacterial count, which are the key parameters for immunogenicity evaluation. These quality parameters were compared using test results submitted by the manufacturer and obtained at the testing centre. The authors plotted individuals charts (X-charts) and moving range charts (R-charts) in accordance with national standards GOST R 50779.42-99 and GOST R ISO 7870-2-2015.Results. The quality of the BCG and BCG-M vaccines remained stable during the entire follow-up period (2019–2022). For some periods, the retrospective analysis of R- and X-charts revealed characteristic trends meeting special cause criteria. The Pearson correlation coefficient (r) between the data submitted by the manufacturer and the data obtained at the testing centre ranged from 0.2 to 0.8.Conclusions. The Shewhart charts demonstrated that the quality parameters of the BCG and BCG-M tuberculosis vaccines tested in 2019–2022 were stable. These vaccines had stable manufacturing processes, as shown by the R- and X-charts. However, the warning signs indicated that additional measures should be taken to standardise the manufacturing processes. The findings suggest that Shewhart charts may be recommended for monitoring the production and quality of tuberculosis vaccines