Influence of individual behavioral risk factors (smoking, drinking) on mortality in the population cohort of adult people 20—59 years old in Tomsk (17-year prospective study)

In 17-year prospective cohort study, we analyzed the influence of smoking and drinking on the formation of cardiovascular and general mortality of adult people in Tomsk. The cohort included 1 546 people (630 men and 916 women) aged 20—59 years. It has been found that due to smoking the 17-year risk of death by any cause increases 2.4 times among men and 2.7 times among women. The increase in the frequency of drinking in the male population increase the risk of death by any cause 1.6 times (for men drinking once a month or more rarely), 2.4 times (for men drinking once a week and more rarely, but more often than once a month), and 3.8 times (for men drinking more often than once a week). The risk of death by cardiovascular diseases increases 1.7, 2.9, and 4.9 times, respectively

Dynamics of arterial hypertension depending on change of weight

In 17-year cohort p1rospective study, the dynamics of arterial hypertension (AH) and arterial pressure (AP) levels has been examined as functions of the boy mass. The cohort included 630 men and 916 women aged from 20 to 59. The overweight was diagnosed at the Body Mass Index index no lower than 25 kg/m2.In the primary research, the AH prevalence rate was 35,7% among overweighted people and 12,5% (р < 0,001) among people with normal weight. In the 17-year observation, the increase of the body mass up to overweight was accompanied by an increase in the AH rate and AP levels, while the decrease of the body mass down to the normal one was accompanied by a decrease of these indices (except only for men aged from 40 to 59). Among overweighted people revealed at the I and II stages of the study, the systolic ((155,71 ± 28,59) mmHg) and diastolic ((93,68 ± 13,77) mm Hg) AH was higher than that in people, who became overweighted the observation: (137,08 ± 23,02) and (86,73 ± 12,19) mm Hg, respectively (р < 0,001)

Natural dynamics of hypertriglyceridemia: incidence, regression, mortality from cardiovascular diseases and all causes (according to the results of a 17-years prospective study)

In 17-year nested prospective study, the natural dynamics of hypertriglyceridemia (HTG) (development of new cases, regress), cardiovascular mortality and other mortality of patients with HTG have been examined. The nest included 630 men and 916 women from 20 to 59 years old. The HTG incident in the nest was 8.24 cases per 1000 people*years of observation. Among people 20—29 years old, new HTG cases were observed more often in men, while in the age interval of 30—59 years, new cases were more often observed in women. For the period of observation, the HTG occurrence increased 1.6 times in men and 2.1 times in women. HTG is characterized by the low course stability, and the regress level is independent of sex. Among men and women, Among men and women with HTG, brain stroke and cardiovascular mortality is higher than that among people with the normal triglyceride (TG) level. The TG level did not affect the total men mortality