Modern approaches to diagnosis and treatment of urethral strictures: literature review and own experience

This article presents a literature review of modern methods of diagnosis and treatment for urethral strictures. In addition, the own results of a pilot study on the use of synthetic tissue-engineering structures as a material for urethroplasty substitution are presented as well

Использование мезенхимных стволовых клеток в терапии туберкулеза

This review presents data from 29 publications on the use of mesenchymal stem cells in the therapy of tuberculosis of various localizations. It also describes some mechanisms of interaction between mesenchymal stem cells and M. tuberculosis.В обзоре представлены данные из 29 источников литературы, посвященных использованию мезенхимных стволовых клеток в терапии туберкулеза различной локализации. Также описаны некоторые механизмы взаимодействия мезенхимных стволовых клеток с M. tuberculosis

Porous composite prosthetic pylon for integration with skin and bone

This article presents results of the further development and testing of the skin and bone integrated pylon (SBIP-1) for percutaneous (through skin) connection of the residual bone with an external limb prosthesis. We investigated a composite structure (called the SBIP-2) made of titanium particles and fine wires using mathematical modeling and mechanical testing. Results showed that the strength of the pylon was comparable with that of anatomical bone. In vitro and in vivo animal studies on 30 rats showed that the reinforcement of the composite pylon did not compromise its previously shown capacity for inviting skin and bone cell ingrowth through the device. These findings provide evidence for the safe and reliable long-term percutaneous transfer of vital and therapeutic substances, signals, and necessary forces and moments from a prosthetic device to the body