Cathodoluminescence and Cross-sectional Transmission Electron Microscopy Studies for Deformation Behaviors of GaN Thin Films Under Berkovich Nanoindentation

In this study, details of Berkovich nanoindentation-induced mechanical deformation mechanisms of metal-organic chemical-vapor deposition-derived GaN thin films have been systematic investigated with the aid of the cathodoluminescence (CL) and the cross-sectional transmission electron microscopy (XTEM) techniques. The multiple “pop-in” events were observed in the load-displacement (P–h) curve and appeared to occur randomly by increasing the indentation load. These instabilities are attributed to the dislocation nucleation and propagation. The CL images of nanoindentation show very well-defined rosette structures with the hexagonal system and, clearly display the distribution of deformation-induced extended defects/dislocations which affect CL emission. By using focused ion beam milling to accurately position the cross-section of an indented area, XTEM results demonstrate that the major plastic deformation is taking place through the propagation of dislocations. The present observations are in support to the massive dislocations activities occurring underneath the indenter during the loading cycle. No evidence of either phase transformation or formation of micro-cracking was observed by means of scanning electron microscopy and XTEM observations. We also discuss how these features correlate with Berkovich nanoindentation produced defects/dislocations structures

Shakura-Sunyaev Disk Can Smoothly Match Advection-Dominated Accretion Flow

We use the standard Runge-Kutta method to solve the set of basic equations describing black hole accretion flows composed of two-temperature plasma. We do not invoke any extra energy transport mechanism such as thermal conduction and do not specify any ad hoc outer boundary condition for the advection-dominated accretion flow (ADAF) solution. We find that in the case of high viscosity and non-zero radiative cooling, the ADAF solution can have an asymptotic approach to the Shakura-Sunyaev disk (SSD) solution, and the SSD-ADAF transition radius is close to the central black hole. Our results further prove the mechanism of thermal instability-triggered SSD-ADAF transition suggested previously by Takeuchi & Mineshige and Gu & Lu.Comment: 10 pages, 2 figures, accepted for publication in ApJ Letter

Global Dynamics of Advection-Dominated Accretion Revisited

We numerically solve the set of dynamical equations describing advection-dominated accretion flows (ADAF) around black holes, using a method similar to that of Chakrabarti (1996a). We choose the sonic radius of the flow $R_s$ and the integration constant in angular momentum equation $j$ as free parameters, and integrate the equations from the sonic point inwards to see if the solution can extend supersonically to the black hole horizon, and outwards to see if and where an acceptable outer boundary of the flow can be found. We recover the ADAF-thin disk solution constructed in Narayan, Kato, & Honma (1997, NKH97), an representative paper of the previous works on global ADAF solutions, although in that paper an apparently very different procedure was adopted. We obtain a complete picture in the form of $R_s-j$ parameter space which sums up the situation of ADAF solution at a glance. For comparison we also present the distribution of global solutions for inviscid flows in the $R_s-j$ space, which supports the view that there should be some similarities between the dynamical behavior of ADAF and that of adiabatic flows, and that there should be a continuous change from the properties of viscous flows to those of inviscid ones.Comment: 24 pages with 15 figures, to appear in ApJ Vol. 52

A Note on the Slim Accretion Disk Model

We show that when the gravitational force is correctly calculated in dealing with the vertical hydrostatic equilibrium of black hole accretion disks, the relationship that is valid for geometrically thin disks, i.e., $c_s/\Omega_K H =$ constant, where $c_s$ is the sound speed, $\Omega_K$ is the Keplerian angular velocity, and $H$ is the half-thickness of the disk, does not hold for slim disks. More importantly, by adopting the correct vertical gravitational force in studies of thermal equilibrium solutions, we find that there exists a maximally possible accretion rate for each radius in the outer region of optically thick accretion flows, so that only the inner region of these flows can possibly take the form of slim disks, and strong outflows from the outer region are required to reduce the accretion rate in order for slim disks to be realized.Comment: 14 pages, 5 figures, accepted by Ap

Studies of Thermally Unstable Accretion Disks around Black Holes with Adaptive Pseudo-Spectral Domain Decomposition Method I. Limit-Cycle Behavior in the Case of Moderate Viscosity

We present a numerical method for spatially 1.5-dimensional and time-dependent studies of accretion disks around black holes, that is originated from a combination of the standard pseudo-spectral method and the adaptive domain decomposition method existing in the literature, but with a number of improvements in both the numerical and physical senses. In particular, we introduce a new treatment for the connection at the interfaces of decomposed subdomains, construct an adaptive function for the mapping between the Chebyshev-Gauss-Lobatto collocation points and the physical collocation points in each subdomain, and modify the over-simplified 1-dimensional basic equations of accretion flows to account for the effects of viscous stresses in both the azimuthal and radial directions. Our method is verified by reproducing the best results obtained previously by Szuszkiewicz & Miller on the limit-cycle behavior of thermally unstable accretion disks with moderate viscosity. A new finding is that, according to our computations, the Bernoulli function of the matter in such disks is always and everywhere negative, so that outflows are unlikely to originate from these disks. We are encouraged to study the more difficult case of thermally unstable accretion disks with strong viscosity, and wish to report our results in a subsequent paper.Comment: 29 pages, 8 figures, accepted by Ap

Delayed Airway Obstruction after Internal Jugular Venous Catheterization in a Patient with Anticoagulant Therapy

Delayed onset of neck hematoma following central venous catheterization without arterial puncture is uncommon. Herein, we present a patient who developed a delayed neck hematoma after repeated attempts at right internal jugular venous puncture and subsequent enoxaparin administration. Progressive airway obstruction occurred on the third day after surgery. Ultrasound examination revealed diffuse hematoma of the right neck, and fibreoptic examination of the airway revealed pharyngeal edema. After emergent surgical removal of the hematoma, the patient was extubated uneventfully

Surface Morphological and Nanomechanical Properties of PLD-Derived ZnO Thin Films

This study reports the surface roughness and nanomechanical characteristics of ZnO thin films deposited on the various substrates, obtained by means of atomic force microscopy (AFM), nanoindentation and nanoscratch techniques. ZnO thin films are deposited on (a- and c-axis) sapphires and (0001) 6H-SiC substrates by using the pulsed-laser depositions (PLD) system. Continuous stiffness measurements (CSM) technique is used in the nanoindentation tests to determine the hardness and Young’s modulus of ZnO thin films. The importance of the ratio (H/Efilm) of elastic to plastic deformation during nanoindentation of ZnO thin films on their behaviors in contact-induced damage during fabrication of ZnO-based devices is considered. In addition, the friction coefficient of ZnO thin films is also presented here

The role of the outer boundary condition in accretion disk models: theory and application

The influence of the outer boundary condition (OBC) on the dynamics and radiation of optically thin accretion flow is investigated. Bremsstrahlung and synchrotron radiations amplified by Comptonization are taken into account and two-temperature plasma assumption is adopted. The three OBCs we adopted are the temperatures of the electrons and ions and the specific angular momentum of the accretion flow at a certain outer boundary. We find that when the general parameters such as the mass accretion rate and the viscous parameter are fixed, the peak flux at various bands such as radio, IR and X-ray, can differ by as large as several orders of magnitude under different OBCs in our example. Our results indicate that OBC is both dynamically and radiatively important therefore should be regarded as a new ``parameter'' in accretion disk models. We apply the above results to the compact radio source Sgr A* and find that the discrepancy between the mass accretion rate favored by ADAF models in the literature and that favored by the three dimensional hydrodynamical simulation can be naturally resolved by seriously considering the outer boundary condition of the accretion flow.Comment: 23 pages, 9 figures,accepted by the Astrophysical Journa

Emodin, a Naturally Occurring Anthraquinone Derivative, Ameliorates Dyslipidemia by Activating AMP-Activated Protein Kinase in High-Fat-Diet-Fed Rats

The aim of this study was to investigate the antiobesity and antihyperlipidaemic effects of emodin on high-fat diet (HFD)-induced obese rats, and on the regulation of the expression of the genes involved in lipid metabolism to elucidate the mechanisms. After being fed HFD for two weeks, Wistar rats were dosed orally with emodin (40 and 80 mg kg−1) or pioglitazone (20 mg kg−1), once daily for eight weeks. Emodin (80 mg kg−1 per day) displayed similar characteristics to pioglitazone (20 mg kg−1 per day) in reducing body weight gain, plasma lipid levels as well as coronary artery risk index and atherogenic index of HFD-fed rats. Emodin also caused dose related reductions in the hepatic triglyceride and cholesterol contents and lowered hepatic lipid droplets accumulation in HFD-fed rats. Emodin and pioglitazone enhanced the phosphorylation of AMP-activated protein kinase (AMPK) and its primary downstream targeting enzyme, acetyl-CoA carboxylase, up-regulated gene expression of carnitine palmitoyl transferase 1, and down-regulated sterol regulatory element binding protein 1 and fatty acid synthase protein levels in hepatocytes of HFD-fed rats. Our findings suggest emodin could attenuate lipid accumulation by decreasing lipogenesis and increasing mitochondrial fatty acid β-oxidation mediated by activation of the AMPK signaling pathway

Effects of human parvovirus B19 VP1 unique region protein on macrophage responses

<p>Abstract</p> <p>Background</p> <p>Activity of secreted phospholipase A (sPLA2) has been implicated in a wide range of cellular responses. However, little is known about the function of human parvovirus B19-VP1 unique region (VP1u) with sPLA2 activity on macrophage.</p> <p>Methods</p> <p>To investigate the roles of B19-VP1u in response to macrophage, phospholipase A2 activity, cell migration assay, phagocytosis activity, metalloproteinase assay, RT-PCR and immunoblotting were performed.</p> <p>Results</p> <p>In the present study, we report that migration, phagocytosis, IL-6, IL-1β mRNA, and MMP9 activity are significantly increased in RAW264.7 cells by B19-VP1u protein with sPLA2 activity, but not by B19-VP1uD175A protein that is mutated and lacks sPLA2 activity. Additionally, significant increases of phosphorylated ERK1/2 and JNK proteins were detected in macrophages that were treated with B19-VP1u protein, but not when they were treated with B19-VP1uD175A protein.</p> <p>Conclusion</p> <p>Taken together, our experimental results suggest that B19-VP1u with sPLA2 activity affects production of IL-6, IL-1β mRNA, and MMP9 activity, possibly through the involvement of ERK1/2 and JNK signaling pathways. These findings could provide clues in understanding the role of B19-VP1u and its sPLA2 enzymatic activity in B19 infection and B19-related diseases.</p