61 research outputs found
Major combined electrolyte deficiency during therapy with low-dose Cisplatin, 5-Fluorouracil and Interferon alpha: report on several cases and review of the literature [ISRCTN62866759]
BACKGROUND: Low-dose Cisplatin and Interferon alpha treatment of solid tumors rarely has been associated with severe hypocalcaemia. To the authors knowledge the phenomenon has not been reported previously in patients with pancreatic carcinoma. CASE PRESENTATION: A patient with resected adenocarcinoma of the pancreas was treated with adjuvant radio-chemo-immunotherapy using a combination of low-dose Cisplatin, 5-Fluorouracil and Interferon alpha together with external beam radiation. Severe hypocalcaemia without signs of acute renal failure or electrolyte disturbance occurred within 2 days at the 4th week of treatment and required intensive care treatment. CONCLUSION: Combination of biological and cytotoxic therapies may increase the incidence of severe hypocalcaemia in pancreatic cancer. Oncologists should remain attentive of this problem as more highly active regimes become available
Transcriptional response to sulfide in the Echiuran Worm Urechis unicinctus by digital gene expression analysis
Respiration in Eggs of the Echiuroid, Urechis unicinctus, Before and After Fertilization. echiuroid eggs/fertilization/respiration/redox dyes/uncoupler of oxidative phosphorylation
Inhibition of Respiration in Sea Urchin Spermatozoa Following Interaction with Fixed Unfertilized Eggs V. Inhibition of Electron Transport in a Span of Mitochondrial Respiratory Chain between Cytochrome b and Cytochrome c in Sea Urchin Spermatozoa, Induced by the Interaction with Glutaraldehyde Fixed Eggs. (sea urchin/sperm/respiration/cytochrome/egg-sperm interaction)
Cloning and expression of high choriolytic enzyme, a component of the hatching enzyme system, during the embryonic development of the marine ornamental fish Chrysiptera parasema
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