20 research outputs found
Copper(II) and Cobalt(III) Pyridoxal Thiosemicarbazone Complexes with Nitroprusside as Counterion: Syntheses, Electronic Properties, and Antileukemic Activity
In this paper the syntheses of new pyridoxal thiosemicarbazone copper(II) and cobalt(III)
complexes with nitroprusside as a counterion and tests on the antileukemic activity of three of
these complexes toward human cell lines U937 and CEM are reported. Nitroprusside was chosen
in order to test if its ability to release NO can increase the biological activity already shown by
these complexes. The compounds were characterized by spectroscopic and magnetic methods
and by single-crystal X-ray diffraction