423 research outputs found
The Milky Way Bulge: Observed properties and a comparison to external galaxies
The Milky Way bulge offers a unique opportunity to investigate in detail the
role that different processes such as dynamical instabilities, hierarchical
merging, and dissipational collapse may have played in the history of the
Galaxy formation and evolution based on its resolved stellar population
properties. Large observation programmes and surveys of the bulge are providing
for the first time a look into the global view of the Milky Way bulge that can
be compared with the bulges of other galaxies, and be used as a template for
detailed comparison with models. The Milky Way has been shown to have a
box/peanut (B/P) bulge and recent evidence seems to suggest the presence of an
additional spheroidal component. In this review we summarise the global
chemical abundances, kinematics and structural properties that allow us to
disentangle these multiple components and provide constraints to understand
their origin. The investigation of both detailed and global properties of the
bulge now provide us with the opportunity to characterise the bulge as observed
in models, and to place the mixed component bulge scenario in the general
context of external galaxies. When writing this review, we considered the
perspectives of researchers working with the Milky Way and researchers working
with external galaxies. It is an attempt to approach both communities for a
fruitful exchange of ideas.Comment: Review article to appear in "Galactic Bulges", Editors: Laurikainen
E., Peletier R., Gadotti D., Springer Publishing. 36 pages, 10 figure
Dynamics of Gaseous Disks in a Non-axisymmetric Dark Halo
The dynamics of a galactic disk in a non-axisymmetric (triaxial) dark halo is
studied in detail using high-resolution, numerical, hydrodynamical models. A
long-lived, two-armed spiral pattern is generated for a wide range of
parameters. The spiral structure is global, and the number of turns can be two
or three, depending on the model parameters. The morphology and kinematics of
the spiral pattern are studied as functions of the halo and disk parameters.
The spiral structure rotates slowly, and its angular velocity varies
quasi-periodically. Models with differing relative halo masses, halo semi-axis
ratios, distributions of matter in the disk, Mach numbers in the gaseous
component, and angular rotational velocities of their halos are considered.Comment: 22 pages, 11 figure
The hitchhiker's guide to decidability and complexity of equivalence properties in security protocols
International audiencePrivacy-preserving security properties in cryptographic protocols are typically modelled by observational equivalences in process calculi such as the applied pi-calulus. We survey decidability and complexity results for the automated verification of such equivalences, casting existing results in a common framework which allows for a precise comparison. This unified view, beyond providing a clearer insight on the current state of the art, allowed us to identify some variations in the statements of the decision problems-sometimes resulting in different complexity results. Additionally, we prove a couple of novel or strengthened results
Relating basic properties of bright early-type dwarf galaxies to their location in Abell 901/902
We present a study of the population of bright early-type dwarf galaxies in
the multiple-cluster system Abell 901/902. We use data from the STAGES survey
and COMBO-17 to investigate the relation between the color and structural
properties of the dwarfs and their location in the cluster. The definition of
the dwarf sample is based on the central surface brightness and includes
galaxies in the luminosity range -16 >= M_B >~-19 mag. Using a fit to the color
magnitude relation of the dwarfs, our sample is divided into a red and blue
subsample. We find a color-density relation in the projected radial
distribution of the dwarf sample: at the same luminosity dwarfs with redder
colors are located closer to the cluster centers than their bluer counterparts.
Furthermore, the redder dwarfs are on average more compact and rounder than the
bluer dwarfs. These findings are consistent with theoretical expectations
assuming that bright early-type dwarfs are the remnants of transformed
late-type disk galaxies involving processes such as ram pressure stripping and
galaxy harassment. This indicates that a considerable fraction of dwarf
elliptical galaxies in clusters are the results of transformation processes
related to interactions with their host cluster.Comment: 12 pages, 8 figures, accepted for publication in A&A, typo corrected
in abstrac
Galaxy Collisions - Dawn of a New Era
The study of colliding galaxies has progressed rapidly in the last few years,
driven by observations with powerful new ground and space-based instruments.
These instruments have used for detailed studies of specific nearby systems,
statistical studies of large samples of relatively nearby systems, and
increasingly large samples of high redshift systems. Following a brief summary
of the historical context, this review attempts to integrate these studies to
address the following key issues. What role do collisions play in galaxy
evolution, and how can recently discovered processes like downsizing resolve
some apparently contradictory results of high redshift studies? What is the
role of environment in galaxy collisions? How is star formation and nuclear
activity orchestrated by the large scale dynamics, before and during merger?
Are novel modes of star formation involved? What are we to make of the
association of ultraluminous X-ray sources with colliding galaxies? To what do
degree do mergers and feedback trigger long-term secular effects? How far can
we push the archaeology of individual systems to determine the nature of
precursor systems and the precise effect of the interaction? Tentative answers
to many of these questions have been suggested, and the prospects for answering
most of them in the next few decades are good.Comment: 44 pages, 9 figures, review article in press for Astrophysics Update
Vol.
Case Report: ISG15 deficiency caused by novel variants in two families and effective treatment with Janus kinase inhibition
ISG15 deficiency is a rare disease caused by autosomal recessive variants in the ISG15 gene, which encodes the ISG15 protein. The ISG15 protein plays a dual role in both the type I and II interferon (IFN) immune pathways. Extracellularly, the ISG15 protein is essential for IFN-γ-dependent anti-mycobacterial immunity, while intracellularly, ISG15 is necessary for USP18-mediated downregulation of IFN-α/β signalling. Due to this dual role, ISG15 deficiency can present with various clinical phenotypes, ranging from susceptibility to mycobacterial infection to autoinflammation characterised by necrotising skin lesions, intracerebral calcification, and pulmonary involvement. In this report, we describe novel variants found in two different families that result in complete ISG15 deficiency and severe skin ulceration. Whole exome sequencing identified a heterozygous missense p.Q16X ISG15 variant and a heterozygous multigene 1p36.33 deletion in the proband from the first family. In the second family, a homozygous total ISG15 gene deletion was detected in two siblings. We also conducted further analysis, including characterisation of cytokine dysregulation, interferon-stimulated gene expression, and p-STAT1 activation in lymphocytes and lesional tissue. Finally, we demonstrate the complete and rapid resolution of clinical symptoms associated with ISG15 deficiency in one sibling from the second family following treatment with the Janus kinase (JAK) inhibitor baricitinib
Towards a canonical classical natural deduction system
This paper studies a new classical natural deduction system, presented as a typed calculus named \lml. It is designed to be
isomorphic to Curien-Herbelin's calculus, both at the level of proofs and reduction, and the isomorphism is based on the correct correspondence between cut (resp. left-introduction) in sequent calculus, and substitution (resp. elimination) in natural deduction. It is a combination of Parigot's -calculus with the idea
of ``coercion calculus'' due to Cervesato-Pfenning, accommodating let-expressions in a surprising way: they expand Parigot's syntactic class of named terms.
This calculus aims to be the simultaneous answer to three problems. The first problem is the lack of a canonical natural deduction
system for classical logic. \lml is not yet another classical calculus, but rather a canonical reflection in natural deduction of
the impeccable treatment of classical logic by sequent calculus. The second problem is the lack of a formalization of the usual semantics
of Curien-Herbelin's calculus, that explains co-terms and cuts as, respectively, contexts and hole-filling instructions. The mentioned
isomorphism is the required formalization, based on the precise notions of context and hole-expression offered by \lml. The third
problem is the lack of a robust process of ``read-back'' into natural deduction syntax of calculi in the sequent calculus format,
that affects mainly the recent proof-theoretic efforts of derivation of -calculi for call-by-value. An isomorphic counterpart
to the -subsystem of Curien-Herbelin's-calculus is derived, obtaining a new
-calculus for call-by-value, combining control and let-expressions.Fundação para a Ciência e a Tecnologia (FCT
Effects of growth rate, size, and light availability on tree survival across life stages: a demographic analysis accounting for missing values and small sample sizes.
The data set supporting the results of this article is available in the Dryad repository, http://dx.doi.org/10.5061/dryad.6f4qs. Moustakas, A. and Evans, M. R. (2015) Effects of
growth rate, size, and light availability on tree survival across life stages: a demographic analysis accounting for missing values.Plant survival is a key factor in forest dynamics and survival probabilities often vary across life stages. Studies specifically aimed at assessing tree survival are unusual and so data initially designed for other purposes often need to be used; such data are more likely to contain errors than data collected for this specific purpose
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