Heat-shock proteins in infection-mediated inflammation-induced tumorigenesis

Inflammation is a necessary albeit insufficient component of tumorigenesis in some cancers. Infectious agents directly implicated in tumorigenesis have been shown to induce inflammation. This process involves both the innate and adaptive components of the immune system which contribute to tumor angiogenesis, tumor tolerance and metastatic properties of neoplasms. Recently, heat-shock proteins have been identified as mediators of this inflammatory process and thus may provide a link between infection-mediated inflammation and subsequent cancer development. In this review, the role of heat-shock proteins in infection-induced inflammation and carcinogenesis will be discussed

Textured MAPbI3 Thin Films Achieved via Solvent Engineering in the Solution‐Shearing Process

Solvent mixtures for making uniform, crystalline methylammonium lead iodide (MAPbI3) perovskite films are provided. The solvents dimethyl sulfoxide (DMSO), γ‐butyrolactone (GBL), and 1‐methyl‐2‐pyrrolidinone (NMP) are examined as well as their binary combinations to prepare solution‐sheared perovskite films at higher than 150 °C temperatures. Characterization methods such as imaging, X‐ray diffraction, grazing‐incidence wide‐angle X‐ray scattering, and photoluminescence (PL) to evaluate the crystal size, quality, and ordering that determine the viability of these films for device applications are explored and then a perovskite solar cell is made to test the stability of the most promising film. Excellent macroscopic crystals, over 1 mm in length, are achieved using a solvent mixture containing equal volumes of DMSO and NMP. These superior 3D MAPbI3 films, which retain solvent–perovskite intermediate phases and exhibit high crystalline ordering, are essential for high‐performing and stable optoelectronic devices