Experimental and Finite Element Modal Analyses of Planar Mechanisms With Three- Dimensional Geometries

Background and Objective In designing a high-performance mechanism for proper dynamic characteristics, its natural frequencies should be a key design factor because they influence its operating speed and the amplitudes and settling times of its vibrations. Natural frequencies of a planar mechanism system is influenced by the inertia and flexibiUty of the links and joints, link offsets, and components comprising the drive and load shafts. The geometry of a kinematically planar mechanism is essentially three dimension (3D) due to the inevitable presence of link offsets dictated by the task and geometric constraints. Link offsets increase the flexibility of the mechanism system, lowers its natural frequency and may cause out-of-plane vibrations to dominate. Furthermore, the inherent compliance and inertia of the drive and load train components such as the driving unit, couphngs, transmission mechanisms, and connecting shafts may influence linkage response by lowering its natural frequencies. Therefore, a reliable model of a planar mechanism should include the influence of all its components rather than its links only

Histopathological effects of maternal hair dye use on the cornea

The aim of this study is to investigate and compare the histopathological effects of hair dye additives, 2- amino-5-nitrophenol (2A5NP) and 2-nitro-p-phenylendiamin (2NPPD) on cornea of neonates from pregnant rats that have been administered these additives subcutaneously. The study included 90 neonates of 26 nulligravida wistar-albino rats among which ten were given 100 mg/kg/day 2A5NP (Group I), ten rats received 150 mg/kg/day 2NPPD (Group II) and control rats received saline (Group III) injections subcutaneously between 7th and 15th gestational days. No sign of toxicity was observed during the treatment and there was no gross abnormality in both the study and control groups. Histopathologicalchanges of cornea were seen in 22 of 30 newborn rats in Group I (73.4%), in 23 of 30 rats in Group II (76.7%) and only 5 of 30 rats in the control saline injected Group III (16.7%). Histopathological effect of the two additives were statistically significant when compared to the control group (Chi-square:27.63, p = 0.0001), but there was no difference between the effects of 2A5NP and 2NPPD additives on cornea (Chisquare: 0.089, p = 0.766). The present experimental study on rats confirmed the histopathological effect of 2A5NP and 2NPPD on cornea beyond doubt. In the light of which, we can speculate that maternal exposure of hair dyes during pregnancy has some teratogenic effects on newborn rat cornea

Casimir force between surfaces close to each other

Casimir interactions (due to the massless scalar field fluctuations) of two surfaces which are close to each other are studied. After a brief general presentation, explicit calculations for co-axial cylinders, co-centric spheres and co-axial cones are performed.Comment: Latex, 20 pages, added references, corrected typos, changed conten

Reply to the Comment by B. Andresen

All the comments made by Andresen's comments are replied and are shown not to be pertinent. The original discussions [ABE S., Europhys. Lett. 90 (2010) 50004] about the absence of nonextensive statistical mechanics with q-entropies for classical continuous systems are reinforced.Comment: 5 pages. This is Reply to B. Andresen's Comment on the paper entitled "Essential discreteness in generalized thermostatistics with non-logarithmic entropy", Europhys. Lett. 90 (2010) 5000

An adaptive, energy-aware and distributed fault-tolerant topology-control algorithm for heterogeneous wireless sensor networks

This paper introduces an adaptive, energy-aware and distributed fault-tolerant topology-control algorithm, namely the Adaptive Disjoint Path Vector (ADPV) algorithm, for heterogeneous wireless sensor networks. In this heterogeneous model, we have resource-rich supernodes as well as ordinary sensor nodes that are supposed to be connected to the supernodes. Unlike the static alternative Disjoint Path Vector (DPV) algorithm, the focus of ADPV is to secure supernode connectivity in the presence of node failures, and ADPV achieves this goal by dynamically adjusting the sensor nodes' transmission powers. The ADPV algorithm involves two phases: a single initialization phase, which occurs at the beginning, and restoration phases, which are invoked each time the network's supernode connectivity is broken. Restoration phases utilize alternative routes that are computed at the initialization phase by the help of a novel optimization based on the well-known set-packing problem. Through extensive simulations, we demonstrate that ADPV is superior in preserving supernode connectivity. In particular, ADPV achieves this goal up to a failure of 95% of the sensor nodes; while the performance of DPV is limited to 5%. In turn, by our adaptive algorithm, we obtain a two-fold increase in supernode-connected lifetimes compared to DPV algorithm. © 2016 Elsevier B.V. All rights reserved

In vivo examination of healthy human skin after short-time treatment with moisturizers using confocal Raman spectroscopy and optical coherence tomography: Preliminary observations

Skin is our barrier against environmental damage. Moisturizers are widely used to increase hydration and barrier integrity of the skin; however, there are contrasting observations on their in vivo effects in real-life settings. In cosmetic studies, cor- neometers and tewameters are traditionally used to assess skin hydration. In this study, two novel noninvasive diagnostic techniques, optical coherence tomography (OCT) and confocal Raman spectroscopy, were used to analyze stratum corneum and epidermal thickness (ET), water content, blood flow in function of depth, skin roughness, attenuation coefficient, natural moisturizing factor, ceramides and free fatty acids, cholesterol, urea, and lactates in 20 female subjects aged between 30 and 45 before and after 2 weeks application of a commercially available mois- turizing lotion on one forearm. The untreated forearm served as control. A third measurement was conducted 1 week after cessation of moisturizing to verify whether the changes in the analyzed parameters persisted. We noticed a reduction in skin roughness, an increase in ceramides and free fatty acids and a not statistically sig- nificant increase in ET. As a conclusion, short time moisturizing appears insufficient to provide significant changes in skin morphology and composition, as assessed by OCT and RS. Novel noninvasive imaging methods are suitable for the evalu- ation of skin response to topical moisturizers. Further studies on larger sample size and longer treatment schedules are needed to analyze changes under treat- ment with moisturizers and to standardize the use of novel noninvasive diagnostic techniques

Antimicrobial susceptibility of bacteria isolated from newborns with suspected or confirmed necrotising enterocolitis

Aim. This audit aimed to identify which bacteria were associated with necrotising enterocolitis (NEC) and determine their antibiotic sensitivities. Methods. A retrospective audit of all infants with a diagnosis of suspected NEC or confirmed NEC and a positive culture (blood/faeces/operative specimen or vascular access device) between January 2000 and September 2007 was performed. Results. Ninety nine infants had a diagnosis of suspected (45) or confirmed NEC (54). Seventeen patients had suspected (5) or confirmed (12) NEC and a positive culture result. 12 babies had positive blood cultures associated with their NEC. Only 4 of the 12 cases of NEC with a positive blood culture received adequate first line cover for their subsequently identified infecting organism. Conclusions. Due to the limitations of this study we are unable to make general recommendations on the first line antibiotic choice for babies with suspected or confirmed NEC. Our current regime of Ampicillin, Gentamicin and Metronidazole failed to adequately treat 8 of the 12 organisms subsequently isolated in blood cultures. Only the combination of Vancomycin and Meropenem would have adequately treated all the bacteria identified. The concern with this approach is the possible emergence of multi drug resistant bacteria

On R\'enyi and Tsallis entropies and divergences for exponential families

Many common probability distributions in statistics like the Gaussian, multinomial, Beta or Gamma distributions can be studied under the unified framework of exponential families. In this paper, we prove that both R\'enyi and Tsallis divergences of distributions belonging to the same exponential family admit a generic closed form expression. Furthermore, we show that R\'enyi and Tsallis entropies can also be calculated in closed-form for sub-families including the Gaussian or exponential distributions, among others.Comment: 7 page