819 research outputs found
Generation of Impulses from Single Frequency Inputs Using Non-linear Propagation in Spherical Chains
This paper investigates the use of chains of spheres to produce impulses. An ultrasonic horn is used to generate high amplitude sinusoidal signals. These are then input into chains of spheres, held together using a minimal force. The result is a non-linear, dispersive system, within which solitary waves can exist. The authors have discovered that resonances can be created, caused by the multiple reflection of solitary waves within the chain. The multiply-reflecting impulses can have a wide bandwidth, due to the inherent nonlinearity of the contact between spheres. It is found that the effect only occurs for certain numbers of spheres in the chain for a given input frequency, a result of the creation of a nonlinear normal mode of resonance. The resulting impulses have many applications, potentially creating high amplitude impulses with adjustable properties, depending on both the nature and number of spheres in the chain, and the frequency and amplitude of excitatio
The effect of boundary conditions on resonant ultrasonic spherical chains
The response of a resonant chain of spheres to changes in holder material and pre-compression is studied at ultrasonic frequencies. The system is found to be very sensitive to these parameters, with the creation of impulsive waveforms from a narrow bandwidth input seen only for certain chain lengths and holder materials. In addition, careful experiments were performed using known amounts of pre-compression force, using a calibrated stylus arrangement. At negligible pre-compression levels, impulses were generated within the chain, which were then suppressed by increased pre-compression. This was accompanied by large changes in propagation velocity as the system gradually changes from being strongly nonlinear to being more linear. Simulations using a discrete model for the motion of each sphere agree well with experimental data
Short- and long-term conditioning of a temperate marine diatom community to acidification and warming
Ocean acidification and greenhouse warming will interactively influence competitive success of key phytoplankton groups such as diatoms, but how long-term responses to global change will affect community structure is unknown. We incubated a mixed natural diatom community from coastal New Zealand waters in a short-term (two-week) incubation experiment using a factorial matrix of warming and/or elevated pCO2 and measured effects on community structure. We then isolated the dominant diatoms in clonal cultures and conditioned them for 1 year under the same temperature and pCO2 conditions from which they were isolated, in order to allow for extended selection or acclimation by these abiotic environmental change factors in the absence of interspecific interactions. These conditioned isolates were then recombined into ‘artificial’ communities modelled after the original natural assemblage and allowed to compete under conditions identical to those in the short-term natural community experiment. In general, the resulting structure of both the unconditioned natural community and conditioned ‘artificial’ community experiments was similar, despite differences such as the loss of two species in the latter. pCO2 and temperature had both individual and interactive effects on community structure, but temperature was more influential, as warming significantly reduced species richness. In this case, our short-term manipulative experiment with a mixed natural assemblage spanning weeks served as a reasonable proxy to predict the effects of global change forcing on diatom community structure after the component species were conditioned in isolation over an extended timescale. Future studies will be required to assess whether or not this is also the case for other types of algal communities from other marine regimes
Estimation of Radiation Dosimetry for 68Ga-HBED-CC (PSMA-11) in Patients with Suspected Recurrence of Prostate Cancer
Introduction
This study was performed to estimate the human radiation dosimetry for [68Ga]Ga-HBED-CC (PSMA-11) (68Ga PSMA-11).
Methods
Under an RDRC-approved research protocol, we evaluated the biodistribution and pharmacokinetics of 68Ga PSMA-11 with serial PET imaging following intravenous administration to nine prostate cancer patients in whom clinical [11C]acetate PET/CT exams had been independently performed under Expanded Access IND 118,204. List-mode imaging was performed over the initial 0–10 min post-injection with the pelvis in the field-of-view. Whole-body images were acquired, pelvis-to-head, at 15, 60, and 90-min post-injection. Additional images of the pelvis were acquired at 40-min and 115-min, and voided urine collected from each subject at 48-min and 120-min post-injection. Radiation dosimetry estimates were calculated from these data using the OLINDA software package.
Results
Renal uptake was high and relatively invariant, ranging from 11% to 14% of the injected dose between 15 and 90-min post-injection. Radioactivity collected in the voided urine accounted for 14% of the injected dose over a period of 120-min. Lymph nodes and skeletal metastases suspicious for prostate cancer recurrence were detected in a greater number of patients using 68Ga PSMA-11 than using 11C-acetate.
Conclusion
Kidneys are the critical organ following 68Ga PSMA-11 administration, receiving an estimated dose of 0.413 mGy/MBq.
Advances in knowledge and implications for patient care
This study confirms that the kidneys will be the critical organ following intravenous administration of 68Ga PSMA-11, and provided data consistent with the expectation that 68Ga PSMA-11 will be superior to [11C]acetate for defining sites of recurrence in prostate cancer patients presenting with biochemical relapse
Theoretical analysis of the electronic structure of the stable and metastable c(2x2) phases of Na on Al(001): Comparison with angle-resolved ultra-violet photoemission spectra
Using Kohn-Sham wave functions and their energy levels obtained by
density-functional-theory total-energy calculations, the electronic structure
of the two c(2x2) phases of Na on Al(001) are analysed; namely, the metastable
hollow-site structure formed when adsorption takes place at low temperature,
and the stable substitutional structure appearing when the substrate is heated
thereafter above ca. 180K or when adsorption takes place at room temperature
from the beginning. The experimentally obtained two-dimensional band structures
of the surface states or resonances are well reproduced by the calculations.
With the help of charge density maps it is found that in both phases, two
pronounced bands appear as the result of a characteristic coupling between the
valence-state band of a free c(2x2)-Na monolayer and the
surface-state/resonance band of the Al surfaces; that is, the clean (001)
surface for the metastable phase and the unstable, reconstructed "vacancy"
structure for the stable phase. The higher-lying band, being Na-derived,
remains metallic for the unstable phase, whereas it lies completely above the
Fermi level for the stable phase, leading to the formation of a
surface-state/resonance band-structure resembling the bulk band-structure of an
ionic crystal.Comment: 11 pages, 11 postscript figures, published in Phys. Rev. B 57, 15251
(1998). Other related publications can be found at
http://www.rz-berlin.mpg.de/th/paper.htm
Early Ultraviolet, Optical and X-Ray Observations of the Type IIP SN 2005cs in M51 with Swift
We report early photospheric-phase observations of the Type IIP Supernova
(SN) 2005cs obtained by Swift's Ultraviolet-Optical and X-Ray Telescopes.
Observations started within two days of discovery and continued regularly for
three weeks. During this time the V-band magnitude remained essentially
constant, while the UV was initially bright but steadily faded until below the
brightness of an underlying UV-bright HII region. This UV decay is similar to
SNe II observed by the International Ultraviolet Explorer. UV grism spectra
show the P-Cygni absorption of MgII 2798A, indicating a photospheric origin of
the UV flux. Based on non-LTE model atmosphere calculations with the CMFGEN
code, we associate the rapid evolution of the UV flux with the cooling of the
ejecta, the peak of the spectral energy distribution (SED) shifting from ~700A
on June 30th to ~1200A on July 5th. Furthermore, the corresponding
recombination of the ejecta, e.g., the transition from FeIII to FeII, induces
considerable strengthening of metal line-blanketing at and above the
photosphere, blocking more effectively this fading UV flux. SN2005cs was not
detected in X-rays, and the upper limit to the X-ray luminosity yields a limit
to the mass loss rate of the progenitor of about 10^-5 solar masses per year.
Overall, Swift presents a unique opportunity to capture the early and fast
evolution of Type II SNe in the UV, providing additional constraints on the
reddening, the SED shortward of 4000A, and the ionization state and temperature
of the photon-decoupling regions.Comment: 15 pages, 6 figures. Accepted for publication by Astrophysical
Journa
The influence of ultra-high-energy cosmic rays on star formation in the early universe
The presence of ultra-high-energy cosmic rays (UHECR) results in an increase
in the degree of ionization in the post-recombination Universe, which
stimulates the efficiency of the production of H molecules and the
formation of the first stellar objects. As a result, the onset of the formation
of the first stars is shifted to higher redshifts, and the masses of the first
stellar systems decrease. As a consequence, a sufficient increase in the
ionizing radiation providing the reionization of the Universe can take place.
We discuss possible observational manifestations of these effects and their
dependence on the parameters of UHECR.Comment: 10 pages, 5 figure
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