A completely automated high inoculation density fed batch process that accommodates clonal diversity and routinely doubles space time yield as compared to low inoculation density processes

Please click Additional Files below to see the full abstract

The Full SPECTRUM: Developing a Tripartite Partnership between Community, Government and Academia for Collaborative Social Policy Research

Problem: In Canadian society, public policies guide the development and administration of social services and systems, including the public education system, the justice system, family services, social housing and income support. However, because social services are often planned and implemented in a ‘siloed’ manner, coordination and collaboration across departments, sectors and organisations is sorely lacking. Data and resource constraints may prevent services being evaluated to ensure they meet the needs of the people for whom they are intended. When the needs of individuals are not addressed, the result is poor outcomes and wasted resources across multiple areas.Our Response: In 2018, we formed the SPECTRUM Partnership in response to a recognised need for collaborative cross-sector approaches to strengthening the policies that shape social services and systems in our country. The tripartite SPECTRUM partnership comprises representatives from community organisations, government and academia, and is an entity designed to conduct social policy research and evaluation, incorporating interdisciplinary perspectives and expertise from its members. Guided by community-driven research questions and building on existing data resources, SPECTRUM seeks to address specific knowledge gaps in social programs, services and systems. New research findings are then translated into viable public policy options, in alignment with government priorities, and presented to policy-makers for consideration.Implications: In this practice-based article, we describe the key steps we took to create the SPECTRUM partnership, build our collective capacity for research and evaluation, and transform our research findings into actionable evidence to support sound public policy. We outline four of SPECTRUM’s achievements to date in the hope that the lessons we learned during the development of the partnership may serve as a guide for others aiming to optimise public policy development in a collaborative evidence-based way

Anatomical Inventories for Person-centred Design in Health Information Systems: A JBI Evidence Synthesis Protocol

Protocol for a scoping review to (a) map the body of literature related to anatomical inventories, (b) examine it to identify key attributes and design features, and (c) develop a model that can be used to support standardization of their design in electronic health records

Immune System and Intergroup Bias: Increases in Cytokines Associated with Worse Evaluations of Resume for Latina Job Applicant

In the present research, we drew on literature in psychoneuroimmunology (PNI) to propose that a hitherto unexplored but potentially important situational factor that may increase intergroup bias is illness and acute inflammation. To examine whether acute inflammation, quantified by increases in salivary cytokines, would lead to greater intergroup bias, we conducted an experiment using a protocol adapted from PNI that increases cytokines via administration of the seasonal influenza vaccine (or saline placebo). Our measures of intergroup bias were a resume evaluation task and an ethnocentrism questionnaire. Providing support for our hypothesis, increases in the cytokine interleukin-1beta were positively associated with intergroup bias. Specifically, participants who experienced greater (vs. lesser) increases in interleukin-1beta rated a Latina applicant as less competent and recommended that she receive a lower starting salary, and demonstrated higher ethnocentrism. Overall, results provide first direct evidence that experimental inductions of immune activity contribute to intergroup bias

Clade I-Associated Mpox Cases Associated with Sexual Contact, the Democratic Republic of the Congo.

We report a cluster of clade I monkeypox virus infections linked to sexual contact in the Democratic Republic of the Congo. Case investigations resulted in 5 reverse transcription PCR-confirmed infections; genome sequencing suggest they belonged to the same transmission chain. This finding demonstrates that mpox transmission through sexual contact extends beyond clade IIb