121 research outputs found
On the Structure of
A new structure for is proposed which it exists in tetragonal
state. In this structure the molecule exists in a nonlinear array
and forms the basis of the tetragonal unit cell with one basis per unit cell.
The structural analysis based on the reflections listed in ASTM 30-1479 shows
that the proposed structure is correct.Comment: six pages and four figures. Manuscript prepared in RevTe
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Foot & Mouth Disease & Ulcerative/Vesicular Rule-outs: Challenges Encountered in Recent Outbreaks
Foot and mouth disease (FMD) is a highly infectious and contagious viral disease affecting bovidae (cattle, zebus, domestic buffaloes, yaks), sheep, goats, swine, all wild ruminants and suidae. Camelidae (camels, dromedaries, llamas, vicunas) have low susceptibility. Foot and mouth disease is caused by a RNS virus of the family Picornaviridae, genus Aphthovirus. There are seven immunologically distinct serotypes: A, O, C, SAT1, SAT2, SAT3, Asia 1. Foot and mouth disease causes significant economic loss both to countries who manage it as an endemic disease (with or without vaccination), as well as those FMD free countries which may become infected. The mortality rate is low in adult animals, but often higher in young due to myocarditis. Foot and mouth disease is endemic in parts of Asia, Africa, the Middle East and South America (sporadic outbreaks in free areas). The Office of International Epizootics (OIE), also referred to the World Organization for Animal Health maintains an official list of free countries and zones.1 The OIE Terrestrial Code (Chapter 2.2.10) provides detailed information on the categories of freedom that can be allocated to a country as well as guidelines for the surveillance for foot and mouth disease (Appendix 3.8.7). In short, countries may be completely free of FMD, free with vaccination or infected with foot and mouth disease virus (FMDV). Source of FMDV include incubating and clinically affected animals with virus present in breath, saliva, faeces, urine, milk and semen. In experimental settings virus has been detected in milk several days before the onset of clinical signs2. Additional sources of virus are meat and by-products in which pH has remained above 6.0 as well as persistently infected carrier animals. Carrier animals may include cattle and water buffalo; convalescent animals and exposed vaccinates (virus persists in the oropharynx for up to 30 months in cattle or longer in buffalo, 9 months in sheep). Pigs do not become carriers. It has been shown that the African Cape buffalo are the major maintenance host of SAT serotypes. FMDV transmission can occur by either direct or indirect contact. Indirect transmission can occur via contaminated animate vectors (humans, etc.), inanimate vectors (vehicles, implements) or airborne transmission. Indirect disease transmission via animate or inanimate vectors can play a major role in disease transmission. Good biosecurity can significantly reduce this type of transmission. Airborne transmission is often debated and is known to be serotype and species specific as well as require specific environmental conditions to occur. Airborne transmission is favored in temperate zones and has been postulated to occur over distances of up to 60 km overland and 300 km by sea. Foot and mouth disease virus is an unenveloped virus which is preserved by refrigeration and freezing and progressively inactivated by temperatures above 50 C. FMDV is highly sensitive to pH change and is inactivated by pH < 6.0 or > 9.0. There are many disinfectants which are effective against FMDV including sodium hydroxide (2%), sodium carbonate (4%), and citric acid (0.2%). FMDV is resistant to iodophores, quaternary ammonium compounds, hypochlorite and phenol, especially in the presence of organic matter. The virus can survive in lymph nodes and bone marrow at neutral pH, but is destroyed in muscle when is pH < 6.0 i.e. after rigor mortis. FMDV can persist in contaminated feed/commodities and the environment for over to 1 month, depending on the temperature and pH conditions. The incubation period for FMD is 2-14 days. Animals transition through latent (infected but not infectious), subclinically infected (infectious but lacking clinical signs) clinically infected and recovered disease states. In cattle clinical signs include pyrexia, reluctance to eat, bruxism, drooling, lameness, treading or stamping of the feet and decreased milk production. Most clinical signs are related to the development and subsequent rupturing of vesicles at the coronary band and in the oral cavity. Vesicles and ulcerations can also occur on the mammary gland. Recovery in adult animals usually occurs in 8-15 days. Clinical signs for most serotypes are less dramatic in sheep and goats. Swine can develop very severe coronary band lesions and high mortality in piglets has been observed. One of the challenges of diagnosing FMD is that it may be clinically similar to several other vesicular or ulcerative diseases. FMD is clinically indistinguishable from Vesicular stomatitis, Swine vesicular disease and Vesicular exanthema of swine. It may also resemble Bovine viral diarrhea, Mucosal disease, Infectious bovine rhinotracheitis, Bluetongue, Bovine papular stomatitis, Bovine mammillitis and Rinderpest
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Modeling Estimated Personnel Needs for a Potential Foot and Mouth Disease Outbreak
Foot and Mouth disease (FMD) is a highly infectious and contagious viral disease affecting cloven-hoofed livestock that was last detected in the United States (US) in 1929. The prevalence of FMD in other countries, as well as the current potential for this virus to be used as a form of agroterrorism, has made preparations for a potential FMD outbreak a national priority. To assist in the evaluation of national preparedness, all 50 states were surveyed via e-mail, telephone and web search to obtain emergency response plans for FMD or for foreign animal diseases in general. Information from 33 states was obtained and analyzed for estimates of personnel resources needed to respond to an outbreak. These estimates were consolidated and enhanced to create a tool that could be used by individual states to better understand the personnel that would be needed to complete various tasks over time during an outbreak response. The estimates were then coupled, post-processing, to the output from FMD outbreaks simulated in California using the Multiscale Epidemiological/Economic Simulation and Analysis (MESA) model at Lawrence Livermore National Laboratory to estimate the personnel resource demands, by task, over the course of an outbreak response
Ferromagnetic redshift of the optical gap in GdN
We report measurements of the optical gap in a GdN film at temperatures from
300 to 6K, covering both the paramagnetic and ferromagnetic phases. The gap is
1.31eV in the paramagnetic phase and red-shifts to 0.9eV in the spin-split
bands below the Curie temperature. The paramagnetic gap is larger than was
suggested by very early experiments, and has permitted us to refine a
(LSDA+U)-computed band structure. The band structure was computed in the full
translation symmetry of the ferromagnetic ground state, assigning the
paramagnetic-state gap as the average of the majority- and minority-spin gaps
in the ferromagnetic state. That procedure has been further tested by a band
structure in a 32-atom supercell with randomly-oriented spins. After fitting
only the paramagnetic gap the refined band structure then reproduces our
measured gaps in both phases by direct transitions at the X point.Comment: 5 pages, 4 figure
A distinct peak-flux distribution of the third class of gamma-ray bursts: A possible signature of X-ray flashes?
Gamma-ray bursts are the most luminous events in the Universe. Going beyond
the short-long classification scheme we work in the context of three burst
populations with the third group of intermediate duration and softest spectrum.
We are looking for physical properties which discriminate the intermediate
duration bursts from the other two classes. We use maximum likelihood fits to
establish group memberships in the duration-hardness plane. To confirm these
results we also use k-means and hierarchical clustering. We use Monte-Carlo
simulations to test the significance of the existence of the intermediate group
and we find it with 99.8% probability. The intermediate duration population has
a significantly lower peak-flux (with 99.94% significance). Also, long bursts
with measured redshift have higher peak-fluxes (with 98.6% significance) than
long bursts without measured redshifts. As the third group is the softest, we
argue that we have {related} them with X-ray flashes among the gamma-ray
bursts. We give a new, probabilistic definition for this class of events.Comment: accepted for publication in Ap
In search of progenitors for supernova-less GRBs 060505 and 060614: re-examination of their afterglows
GRB060505 and GRB060614 are nearby long-duration gamma-ray bursts (LGRBs)
without accompanying supernovae (SNe) down to very strict limits. They thereby
challenge the conventional LGRB-SN connection and naturally give rise to the
question: are there other peculiar features in their afterglows which would
help shed light on their progenitors? To answer this question, we combine new
observational data with published data and investigate the multi-band temporal
and spectral properties of the two afterglows. We find that both afterglows can
be well interpreted within the framework of the jetted standard external shock
wave model, and that the afterglow parameters for both bursts fall well within
the range observed for other LGRBs. Hence, from the properties of the
afterglows there is nothing to suggest that these bursts should have another
progenitor than other LGRBs. Recently, Swift-discovered GRB080503 also has the
spike + tail structure during its prompt gamma-ray emission seemingly similar
to GRB060614. We analyse the prompt emission of this burst and find that this
GRB is actually a hard-spike + hard-tail burst with a spectral lag of
0.80.4 s during its tail emission. Thus, the properties of the prompt
emission of GRB060614 and GRB080503 are clearly different, motivating further
thinking of GRB classification. Finally we note that, whereas the progenitor of
the two SN-less bursts remains uncertain, the core-collapse origin for the
SN-less bursts would be quite certain if a wind-like environment can be
observationally established, e.g, from an optical decay faster than the X-ray
decay in the afterglow's slow cooling phase.Comment: 15 pages, 7 figures, 4 tables, ApJ in press; added Fig. 7 of the
lag-luminosity relatio
The Spectral Lag of GRB060505: A Likely Member of the Long Duration Class
Two long gamma-ray bursts, GRB 060505 and GRB 060614, occurred in nearby
galaxies at redshifts of 0.089 and 0.125 respectively. Due to their proximity
and durations, deep follow-up campaigns to search for supernovae (SNe) were
initiated. However none were found in either case, to limits more than two
orders of magnitude fainter than the prototypical GRB-associated SN, 1998bw. It
was suggested that the bursts, in spite of their durations (4 and 102 s),
belonged to the population of short GRBs which has been shown to be unrelated
to SNe. In the case of GRB 060614 this argument was based on a number of
indicators, including the negligible spectral lag, which is consistent with
that of short bursts. GRB 060505 has a shorter duration, but no spectral lag
was measured. We present the spectral lag measurements of GRB 060505 using
Suzakus Wide Area Monitor and the Swift Burst Alert Telescope. We find that the
lag is 0.36+/- 0.05 s, inconsistent with the lags of short bursts and
consistent with the properties of long bursts and SN-GRBs. These results
support the association of GRB 060505 with other low-luminosity GRBs also found
in star-forming galaxies and indicates that at least some massive stars may die
without bright SNe.Comment: Accepted by ApJL, 5 pages, 3 Figure
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