688 research outputs found
The group structure of non-Abelian NS-NS transformations
We study the transformations of the worldvolume fields of a system of
multiple coinciding D-branes under gauge transformations of the supergravity
Kalb-Ramond field. We find that the pure gauge part of these NS-NS
transformations can be written as a U(N) symmetry of the underlying Yang-Mills
group, but that in general the full NS-NS variations get mixed up non-trivially
with the U(N). We compute the commutation relations and the Jacobi identities
of the bigger group formed by the NS-NS and U(N) transformations.Comment: Latex, 11 pages. v2: Typos corrected; version to appear in JHEP
Matrix theory origins of non-geometric fluxes
We explore the origins of non-geometric fluxes within the context of M theory
described as a matrix model. Building upon compactifications of Matrix theory
on non-commutative tori and twisted tori, we formulate the conditions which
describe compactifications with non-geometric fluxes. These turn out to be
related to certain deformations of tori with non-commutative and
non-associative structures on their phase space. Quantization of flux appears
as a natural consequence of the framework and leads to the resolution of
non-associativity at the level of the unitary operators. The quantum-mechanical
nature of the model bestows an important role on the phase space. In
particular, the geometric and non-geometric fluxes exchange their properties
when going from position space to momentum space thus providing a duality among
the two. Moreover, the operations which connect solutions with different fluxes
are described and their relation to T-duality is discussed. Finally, we provide
some insights on the effective gauge theories obtained from these matrix
compactifications.Comment: 1+31 pages, reference list update
Wikipedia as an encyclopaedia of life
In his 2003 essay E O Wilson outlined his vision for an “encyclopaedia of life” comprising “an electronic page for each species of organism on Earth”, each page containing “the scientific name of the species, a pictorial or genomic presentation of the primary type specimen on which its name is based, and a summary of its diagnostic traits.” Although the “quiet revolution” in biodiversity informatics has generated numerous online resources, including some directly inspired by Wilson's essay (e.g., "http://ispecies.org":http://ispecies.org, "http://www.eol.org":http://www.eol.org), we are still some way from the goal of having available online all relevant information about a species, such as its taxonomy, evolutionary history, genomics, morphology, ecology, and behaviour. While the biodiversity community has been developing a plethora of databases, some with overlapping goals and duplicated content, Wikipedia has been slowly growing to the point where it now has over 100,000 pages on biological taxa. My goal in this essay is to explore the idea that, largely independent of the efforts of biodiversity informatics and well-funded international efforts, Wikipedia ("http://en.wikipedia.org/wiki/Main_Page":http://en.wikipedia.org/wiki/Main_Page) has emerged as potentially the best platform for fulfilling E O Wilson’s vision
Optimal leverage from non-ergodicity
In modern portfolio theory, the balancing of expected returns on investments
against uncertainties in those returns is aided by the use of utility
functions. The Kelly criterion offers another approach, rooted in information
theory, that always implies logarithmic utility. The two approaches seem
incompatible, too loosely or too tightly constraining investors' risk
preferences, from their respective perspectives. The conflict can be understood
on the basis that the multiplicative models used in both approaches are
non-ergodic which leads to ensemble-average returns differing from time-average
returns in single realizations. The classic treatments, from the very beginning
of probability theory, use ensemble-averages, whereas the Kelly-result is
obtained by considering time-averages. Maximizing the time-average growth rates
for an investment defines an optimal leverage, whereas growth rates derived
from ensemble-average returns depend linearly on leverage. The latter measure
can thus incentivize investors to maximize leverage, which is detrimental to
time-average growth and overall market stability. The Sharpe ratio is
insensitive to leverage. Its relation to optimal leverage is discussed. A
better understanding of the significance of time-irreversibility and
non-ergodicity and the resulting bounds on leverage may help policy makers in
reshaping financial risk controls.Comment: 17 pages, 3 figures. Updated figures and extended discussion of
ergodicit
D-branes in Generalized Geometry and Dirac-Born-Infeld Action
The purpose of this paper is to formulate the Dirac-Born-Infeld (DBI) action
in a framework of generalized geometry and clarify its symmetry. A D-brane is
defined as a Dirac structure where scalar fields and gauge field are treated on
an equal footing in a static gauge. We derive generalized Lie derivatives
corresponding to the diffeomorphism and B-field gauge transformations and show
that the DBI action is invariant under non-linearly realized symmetries for all
types of diffeomorphisms and B-field gauge transformations. Consequently, we
can interpret not only the scalar field but also the gauge field on the D-brane
as the generalized Nambu-Goldstone boson.Comment: 32 pages, 4 figures, ver2:typos corrected, references adde
Allelic Exchange of Pheromones and Their Receptors Reprograms Sexual Identity in Cryptococcus neoformans
Cell type specification is a fundamental process that all cells must carry out to ensure appropriate behaviors in response to environmental stimuli. In fungi, cell identity is critical for defining âsexesâ known as mating types and is controlled by components of mating type (MAT) loci. MATâencoded genes function to define sexes via two distinct paradigms: 1) by controlling transcription of components common to both sexes, or 2) by expressing specially encoded factors (pheromones and their receptors) that differ between mating types. The human fungal pathogen Cryptococcus neoformans has two mating types (a and α) that are specified by an extremely unusual MAT locus. The complex architecture of this locus makes it impossible to predict which paradigm governs mating type. To identify the mechanism by which the C. neoformans sexes are determined, we created strains in which the pheromone and pheromone receptor from one mating type (a) replaced the pheromone and pheromone receptor of the other (α). We discovered that these âαaâ cells effectively adopt a new mating type (that of a cells); they sense and respond to α factor, they elicit a mating response from α cells, and they fuse with α cells. In addition, αa cells lose the α cell type-specific response to pheromone and do not form germ tubes, instead remaining spherical like a cells. Finally, we discovered that exogenous expression of the diploid/dikaryon-specific transcription factor Sxi2a could then promote complete sexual development in crosses between α and αa strains. These data reveal that cell identity in C. neoformans is controlled fully by three kinds of MATâencoded proteins: pheromones, pheromone receptors, and homeodomain proteins. Our findings establish the mechanisms for maintenance of distinct cell types and subsequent developmental behaviors in this unusual human fungal pathogen
Stringy effects in black hole decay
We compute the low energy decay rates of near-extremal three(four) charge
black holes in five(four) dimensional N=4 string theory to sub-leading order in
the large charge approximation. This involves studying stringy corrections to
scattering amplitudes of a scalar field off a black hole. We adapt and use
recently developed techniques to compute such amplitudes as near-horizon
quantities. We then compare this with the corresponding calculation in the
microscopic configuration carrying the same charges as the black hole. We find
perfect agreement between the microscopic and macroscopic calculations; in the
cases we study, the zero energy limit of the scattering cross section is equal
to four times the Wald entropy of the black hole.Comment: 32 page
Carbogen-induced changes in rat mammary tumour oxygenation reported by near infrared spectroscopy
We have evaluated the ability of steady-state, radially-resolved, broad-band near infrared diffuse reflectance spectroscopy to measure carbogen-induced changes in haemoglobin oxygen saturation (SO2) and total haemoglobin concentration in a rat R3230 mammary adenocarcinoma model in vivo. Detectable shifts toward higher saturations were evident in all tumours (n = 16) immediately after the onset of carbogen breathing. The SO2 reached a new equilibrium within 1 min and remained approximately constant during 200â300 s of administration. The return to baseline saturation was more gradual when carbogen delivery was stopped. The degree to which carbogen increased SO2 was variable among tumours, with a tendency for tumours with lower initial SO2 to exhibit larger changes. Tumour haemoglobin concentrations at the time of peak enhancement were also variable. In the majority of cases, haemoglobin concentration decreased in response to carbogen, indicating that increased tumour blood volume was not responsible for the observed elevation in SO2. We observed no apparent relationship between the extent of the change in tumour haemoglobin concentration and the magnitude of the change in the saturation. Near infrared diffuse reflectance spectroscopy provides a rapid, non-invasive means of monitoring spatially averaged changes in tumour haemoglobin oxygen saturation induced by oxygen modifiers. © 1999 Cancer Research Campaig
Critical Trapped Surfaces Formation in the Collision of Ultrarelativistic Charges in (A)dS
We study the formation of marginally trapped surfaces in the head-on
collision of two ultrarelativistic charges in space-time. The metric of
ultrarelativistic charged particles in is obtained by boosting
Reissner-Nordstr\"om space-time to the speed of light. We show that
formation of trapped surfaces on the past light cone is only possible when
charge is below certain critical - situation similar to the collision of two
ultrarelativistic charges in Minkowski space-time. This critical value depends
on the energy of colliding particles and the value of a cosmological constant.
There is richer structure of critical domains in case. In this case
already for chargeless particles there is a critical value of the cosmological
constant only below which trapped surfaces formation is possible. Appearance of
arbitrary small nonzero charge significantly changes the physical picture.
Critical effect which has been observed in the neutral case does not take place
more. If the value of the charge is not very large solution to the equation on
trapped surface exists for any values of cosmological radius and energy density
of shock waves. Increasing of the charge leads to decrease of the trapped
surface area, and at some critical point the formation of trapped surfaces of
the type mentioned above becomes impossible.Comment: 30 pages, Latex, 7 figures, Refs. added and typos correcte
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