Dynamic Voltage Scheduling Technique for Low-Power Multimedia Applications Using Buffers

As multimedia applications are used increasingly in many embedded systems, power efficient design for the applications becomes more important than ever. This paper proposes a simple dynamic voltage scheduling technique, which suits the multimedia applications well. The proposed technique fully utilizes the idle intervals with buffers in a variable speed processor. The main theme of this paper is to determine the minimum buffer size to achieve the maximum energy saving in three cases: single-task, multiple subtasks, and multi-task. Experimental results show that the proposed technique is expected to obtain significant power reduction for several real-world multimedia applications

Dynamic Voltage Scheduling with Buffers in Low-Power Multimedia Applications

Power-efficient design of multimedia applications becomes more important as they are used increasingly in many embedded systems. We propose a simple dynamic voltage scheduling technique which suits multimedia applications well and, in case of soft real-time applications, allows all idle intervals of the processor to be fully exploited by using buffers. Our main theme is to determine the minimum buffer size to maximize energy saving in three cases: (i) single-task, (ii) multiple-subtask and (iii) multi-task. We also present a technique of adjusting task deadlines for further reducing energy consumption in the multiple-subtask and multi-task cases. Unlike other DVS techniques using buffers, we guarantee to meet the real-time latency constraint. Experimental results show that the proposed technique does indeed achieve significant power reduction in real-world multimedia applications.This work was supported by National Research Laboratory Program (No. M1-0104-00-0015) and the Brain Korea 21 Project. The ICT at Seoul National University provided research facilities for this study

Dynamic Voltage Scheduling with Buffers in Low-Power Multimedia Applications

this paper is an on-line inter-task DVS technique that can exploit the VST fully using buffers. We target multimedia applications where a buffering delay is tolerable within a latency constraint. The proposed technique is better than the previous inter-task DVS techniques because it fully utilizes both WST and VST. And it is better than the intra-task DVS techniques because it uses much fewer voltage changes at run-time. We aim to minimize the voltage fluctuation because a constant voltage level gives the ideal performanc

Phosphorylated p70S6K in noninvasive low-grade urothelial carcinoma of the bladder: correlation with tumor recurrence

We investigated whether inhibiting phosphorylated p70S6K (p-p70S6K) suppresses the proliferation and growth of noninvasive low-grade urothelial carcinoma (LG-URCa) in vitroand whether p-p70S6K can serve as a predictive biomarker for the recurrence of noninvasive LG-URCa of the bladder in patients. We constructed a tissue microarray (TMA) for 95 LG-URCa and 35 benign urothelium samples and performed immunohistochemical staining for p-p70S6K and p-4E-BP1. A Cox regression model was used to investigate the predictive factors for recurrence of LG-URCa. We investigated the dose-dependent antiproliferative effect of rapamycin, its antiproliferative effect and the growth-inhibition effect of p70S6K siRNA transfection in RT4 and 253J cell lines. The pT1 staged group (P < 0.05; hazard ratio (HR), 2.415) and the high p-p70S6K staining group (P < 0.05; HR, 2.249) were independent factors for predicting recurrence. Rapamycin inhibited RT4 and 253J cell proliferation in a dose-dependent manner (r = −0.850, P< 0.001 in RT4 cells; r = −0.835, P< 0.001 in 253J cells). RT4 and 253J cell proliferation and growth were inhibited by the transfection of p70S6K siRNA and rapamycin, respectively (P < 0.05). Transfection of p70S6K siRNA resulted in inhibitory effects on cell proliferation and growth that were similar to those of rapamycin. Our results suggest that inhibiting p70S6K phosphorylation is important to prevent recurrence and that p70S6K phosphorylation can be used as a molecular biomarker to predict recurrence of certain LG-URCa of the bladder

Cnu, a Novel oriC-Binding Protein of Escherichia coli

We have found, using a newly developed genetic method, a protein (named Cnu, for oriC-binding nucleoid-associated) that binds to a specific 26-base-pair sequence (named cnb) in the origin of replication of Escherichia coli, oriC. Cnu is composed of 71 amino acids (8.4 kDa) and shows extensive amino acid identity to a group of proteins belonging to the Hha/YmoA family. Cnu was previously discovered as a protein that, like Hha, complexes with H-NS in vitro. Our in vivo and in vitro assays confirm the results and further suggest that the complex formation with H-NS is involved in Cnu/Hha binding to cnb. Unlike the hns mutants, elimination of either the cnu or hha gene did not disturb the growth rate, origin content, and synchrony of DNA replication initiation of the mutants compared to the wild-type cells. However, the cnu hha double mutant was moderately reduced in origin content. The Cnu/Hha complex with H-NS thus could play a role in optimal activity of oriC

Cnu, a Novel oriC-Binding Protein of Escherichia coli

We have found, using a newly developed genetic method, a protein (named Cnu, for oriC-binding nucleoid-associated) that binds to a specific 26-base-pair sequence (named cnb) in the origin of replication of Escherichia coli, oriC. Cnu is composed of 71 amino acids (8.4 kDa) and shows extensive amino acid identity to a group of proteins belonging to the Hha/YmoA family. Cnu was previously discovered as a protein that, like Hha, complexes with H-NS in vitro. Our in vivo and in vitro assays confirm the results and further suggest that the complex formation with H-NS is involved in Cnu/Hha binding to cnb. Unlike the hns mutants, elimination of either the cnu or hha gene did not disturb the growth rate, origin content, and synchrony of DNA replication initiation of the mutants compared to the wild-type cells. However, the cnu hha double mutant was moderately reduced in origin content. The Cnu/Hha complex with H-NS thus could play a role in optimal activity of oriC