Activity markers on the anterior dentition of Neandertals: the case of cultural striations

Comunicación presentada en el XIII Encuentro en Jóvenes Investigadores en Paleontología (XIII EJIP) - XIII Meeting of Early-Stage Researchers in Paleontology (XIII EJIP): Cercedilla, 15 - 18 de Abril de 2015Este trabajo ha sido financiado por el proyecto CGL2012-36682 (MINECO)Peer reviewe

Estructura de nave industrial de acero

[EN] This project is based on the calculation of the structure of an industrial ship of steel. In the present project four solutions have been studied and we have chosen the best solution. The ship is in Vall d'Alba (Castellón)[ES] El proyecto esta basado en el cálculo de la estructura de una nave industrial de acero. En el presente proyecto se han estudiado cuatro soluciones y de las cuatro hemos elegido la mas optima para la ejecución de la estructura. La nave se encuentra en Vall d'Alba (Castellón)[CA] El projecte esta basat en el càlcul de l'estructura d'una nau industrial d'acer. En el present projecte s'han estudiat quatre solucions i de les quatre hem triat la mas òptima per a l'execució de l'estructura. La nau es troba en Vall d'Alba (Castelló)Alagarda Huguet, JA. (2014). Estructura de nave industrial de acero. http://hdl.handle.net/10251/39877.Archivo delegad

Distributional solutions of the Beltrami equation

We study the distributional solutions to the (generalized) Beltrami equation under Sobolev assumptions on the Beltrami coefficients. In this setting, we prove that these distributional solutions are true quasiregular maps and they are smoother than expected, that is, they have second order derivatives in Lloc1+ε, for some ε>0

The Efficacy of Therapeutic Respiratory Muscle Training Interventions in People with Bronchiectasis: A Systematic Review and Meta-Analysis

Background: Respiratory muscle dysfunction is an important health problem with high morbidity and mortality and associated costs in patients with bronchiectasis (BC). The aim of this study was to analyse the effects of therapeutic respiratory muscle training (RMT) interventions on improving sputum clearance, ventilator function, muscle strength and functional capacity in BC. Methods: Systematic review and meta-analysis were conducted following PRISMA guidelines. Two independent investigators searched using several electronic databases. The methodological quality of nine studies was assessed using the PEDro scale. Study selection/eligibility criteria: The following were included: randomised controlled trials, randomised crossover trials and pilot studies of patients with BC that used the intervention as RMT (inspiratory/expiratory) and evaluations of respiratory muscle strength (maximal expiratory pressure/maximal inspiratory pressure). This systematic review was registered in PROSPERO (CRD42017075101). Nine studies were included, five of which obtained an A recommendation grade, three with B, and one with C. Study quality was poor to good (mean PEDro Score of 6.375 out of 10). Studies had small sample sizes (8-98). Results show improvements on PImax in favour of therapeutic respiratory muscle training intervention (MD = 6.08; 95% CI = 1.38, 10.77; p < 0.01; I-2 = 92%). However, high heterogeneity was identified on meta-analysis

Genetic evidence for patrilocal mating behaviour among Neandertal groups

The remains of 12 Neandertal individuals have been found at the El Sidrón site (Asturias, Spain), consisting of six adults, three adolescents, two juveniles, and one infant. Archaeological, paleontological, and geological evidence indicates that these individuals represent all or part of a contemporaneous social group of Neandertals, who died at around the same time and later were buried together as a result of a collapse of an underground karst. We sequenced phylogenetically informative positions of mtDNA hypervariable regions 1 and 2 from each of the remains. Our results show that the 12 individuals stem from three different maternal lineages, accounting for seven, four, and one individual(s), respectively. Using a Y-chromosome assay to confirm the morphological determination of sex for each individual, we found that, although the three adult males carried the same mtDNA lineage, each of the three adult females carried different mtDNA lineages. These findings provide evidence to indicate that Neandertal groups not only were small and characterized by low genetic diversity but also were likely to have practiced patrilocal mating behavior.C.L.-F. also is supported by an Intramural Grant from the Consejo Superior de Investigaciones Cientificas. A.R., A.E., M.B., A.G.-T., and S.G.-V. are supported by Grant CGL2009-09013 from the Ministry of Science and Innovation of Spain.Peer reviewe

¿Cómo se influyen la enfermedad inflamatoria intestinal y el estado nutricional? Causas y consecuencias de la malnutrición en la enfermedad inflamatoria intestinal.

La enfermedad inflmatoria intestinal es un grupo de patologías crónicas que incluye, entre otras, la enfermedad de Crohn y la colitis ulcerosa, que se definen por ser entidades que cursan en brotes y que tienen en común una inflamación crónica en el aparato digestivo de un individuo genéticamente predispuesto, dando lugar a unas características clínicas similares. En relación a la nutrición, es interesante conocer cómo ésta puede influir en la patogenia de la enfermedad, cómo puede modificar el pronóstico e, incluso, utilizarse como tratamiento por encima de fármacos como los corticoides o los inmunosupresores. Es importante saber qué nos dice la evidencia científica en lo que al manejo nutricional de la enfermedad se refiere: recomendar un determinado tipo de dieta o no, utilizar ciertos suplementos, hacer un seguimiento para micronutrientes concretos, valorar el estado nutricional del paciente etc. El objetivo de esta revisión es recopilar el conocimiento y las pruebas científicas disponibles a este respecto y poder, así, llevar a cabo un correcto manejo de estos pacientes que les permita tener una mejor calidad de vida, una menor probabilidad de caer en brote, una menor hospitalización y una dependencia menor de fármacos como los corticoesteroides.

Proyecto de instalación fotovoltaica para autoconsumo del edificio Ada Byron

El presente proyecto aborda la instalación de un generador fotovoltaico para autoconsumo de energía renovablesobre la cubierta de un edificio ya construido, el Ada Byron de la Escuela de Ingeniería y Arquitectura.Este proyecto pretende desarrollar los criterios para ahorro de energía que marca el Código Técnico de Edificación.El trabajo tiene un formato de memoria, anexos, planos, pliego de condiciones y presupuesto donde se describe la instalación , la normativa vigente a aplicar y todos aquellos detalles para su ejecución.<br /

A preliminary assessment of the thoracic remains of the El Sidrón Neandertals (Asturias, Spain)

Resumen del póster presentado en: 3rd Annual Meeting of the European Society for the study of Human Evolution, 19-21 September 2013, Vienna/AustriaPeer reviewe

Inventar problemas: una forma de desarrollar las competencias básicas

En esta comunicación presentamos los resultados de una investigación llevada a cabo con alumnos de 2º de ESO en la que estudiamos la relación entre el uso de un programa de intervención en el aula basado en la invención y reconstrucción de situaciones problemáticas y el desarrollo de su competencia matemática y lingüística, observándose una mejoría significativa en los alumnos a los que se les aplicó el programa con respecto al resto

Possible further evidence of low genetic diversity in the El Sidrón (Asturias, Spain) Neandertal group: congenital clefts of the Atlas

Received: June 12, 2015; Accepted: August 5, 2015; Published: September 29, 2015We present here the first cases in Neandertals of congenital clefts of the arch of the atlas. Two atlases from El Sidrón, northern Spain, present respectively a defect of the posterior (frequency in extant modern human populations ranging from 0.73% to 3.84%), and anterior (frequency in extant modern human populations ranging from 0.087% to 0.1%) arch, a condition in most cases not associated with any clinical manifestation. The fact that two out of three observable atlases present a low frequency congenital condition, together with previously reported evidence of retained deciduous mandibular canine in two out of ten dentitions from El Sidrón, supports the previous observation based on genetic evidence that these Neandertals constituted a group with close genetic relations. Some have proposed for humans and other species that the presence of skeletal congenital conditions, although without clinical significance, could be used as a signal of endogamy or inbreeding. In the present case this interpretation would fit the general scenario of high incidence of rare conditions among Pleistocene humans and the specific scenariothat emerges from Neandertal paleogenetics, which points to long-term small and decreasing population size with reduced and isolated groups. Adverse environmental factors affecting early pregnancies would constitute an alternative, non-exclusive, explanation for a high incidence of congenital conditions. Further support or rejection of these interpretations will come from new genetic and skeletal evidence from Neandertal remains.Funding was provided by Ministerio de Economía y Competitividad, Spain, projects CGL2012-36682 and CGL2012-37279.Peer reviewe