Comment on ``New ansatz for metric operator calculation in pseudo-Hermitian field theory''

In a recent Brief Report by Shalaby a new first-order perturbative calculation of the metric operator for an $i\phi^3$ scalar field theory is given. It is claimed that the result is an improvement on a previous calculation by Bender, Brody and Jones because it is local. Unfortunately Shalaby's calculation is not valid because of sign errors.Comment: 2 pages, no figures. This comment replaces the previous comment on the Brief Report by Shalaby. In the previous comment we pointed out that Shalaby's calculation failed in all but 2 space-time dimensions. We have subsequently found additional errors which mean that the calculation is not valid even in that cas

Must a Hamiltonian be Hermitian?

A consistent physical theory of quantum mechanics can be built on a complex Hamiltonian that is not Hermitian but instead satisfies the physical condition of space-time reflection symmetry (PT symmetry). Thus, there are infinitely many new Hamiltonians that one can construct that might explain experimental data. One would think that a quantum theory based on a non-Hermitian Hamiltonian violates unitarity. However, if PT symmetry is not broken, it is possible to use a previously unnoticed physical symmetry of the Hamiltonian to construct an inner product whose associated norm is positive definite. This construction is general and works for any PT-symmetric Hamiltonian. The dynamics is governed by unitary time evolution. This formulation does not conflict with the requirements of conventional quantum mechanics. There are many possible observable and experimental consequences of extending quantum mechanics into the complex domain, both in particle physics and in solid state physics.Comment: Revised version to appear in American Journal of Physic

Using electrostatic potentials to predict DNA-binding sites on DNA-binding proteins

A method to detect DNA-binding sites on the surface of a protein structure is important for functional annotation. This work describes the analysis of residue patches on the surface of DNA-binding proteins and the development of a method of predicting DNA-binding sites using a single feature of these surface patches. Surface patches and the DNA-binding sites were initially analysed for accessibility, electrostatic potential, residue propensity, hydrophobicity and residue conservation. From this, it was observed that the DNA-binding sites were, in general, amongst the top 10% of patches with the largest positive electrostatic scores. This knowledge led to the development of a prediction method in which patches of surface residues were selected such that they excluded residues with negative electrostatic scores. This method was used to make predictions for a data set of 56 non-homologous DNA-binding proteins. Correct predictions made for 68% of the data set

Quantum counterpart of spontaneously broken classical PT symmetry

The classical trajectories of a particle governed by the PT-symmetric Hamiltonian $H=p^2+x^2(ix)^\epsilon$ ($\epsilon\geq0$) have been studied in depth. It is known that almost all trajectories that begin at a classical turning point oscillate periodically between this turning point and the corresponding PT-symmetric turning point. It is also known that there are regions in $\epsilon$ for which the periods of these orbits vary rapidly as functions of $\epsilon$ and that in these regions there are isolated values of $\epsilon$ for which the classical trajectories exhibit spontaneously broken PT symmetry. The current paper examines the corresponding quantum-mechanical systems. The eigenvalues of these quantum systems exhibit characteristic behaviors that are correlated with those of the associated classical system.Comment: 11 pages, 7 figure

Faster than Hermitian Quantum Mechanics

Given an initial quantum state |psi_I> and a final quantum state |psi_F> in a Hilbert space, there exist Hamiltonians H under which |psi_I> evolves into |psi_F>. Consider the following quantum brachistochrone problem: Subject to the constraint that the difference between the largest and smallest eigenvalues of H is held fixed, which H achieves this transformation in the least time tau? For Hermitian Hamiltonians tau has a nonzero lower bound. However, among non-Hermitian PT-symmetric Hamiltonians satisfying the same energy constraint, tau can be made arbitrarily small without violating the time-energy uncertainty principle. This is because for such Hamiltonians the path from |psi_I> to |psi_F> can be made short. The mechanism described here is similar to that in general relativity in which the distance between two space-time points can be made small if they are connected by a wormhole. This result may have applications in quantum computing.Comment: 4 page

WKB Analysis of PT-Symmetric Sturm-Liouville problems

Most studies of PT-symmetric quantum-mechanical Hamiltonians have considered the Schroedinger eigenvalue problem on an infinite domain. This paper examines the consequences of imposing the boundary conditions on a finite domain. As is the case with regular Hermitian Sturm-Liouville problems, the eigenvalues of the PT-symmetric Sturm-Liouville problem grow like $n^2$ for large $n$. However, the novelty is that a PT eigenvalue problem on a finite domain typically exhibits a sequence of critical points at which pairs of eigenvalues cease to be real and become complex conjugates of one another. For the potentials considered here this sequence of critical points is associated with a turning point on the imaginary axis in the complex plane. WKB analysis is used to calculate the asymptotic behaviors of the real eigenvalues and the locations of the critical points. The method turns out to be surprisingly accurate even at low energies.Comment: 11 pages, 8 figure

Bound states of PT-symmetric separable potentials

All of the PT-symmetric potentials that have been studied so far have been local. In this paper nonlocal PT-symmetric separable potentials of the form $V(x,y)=i\epsilon[U(x)U(y)-U(-x)U(-y)]$, where $U(x)$ is real, are examined. Two specific models are examined. In each case it is shown that there is a parametric region of the coupling strength $\epsilon$ for which the PT symmetry of the Hamiltonian is unbroken and the bound-state energies are real. The critical values of $\epsilon$ that bound this region are calculated.Comment: 10 pages, 3 figure