Journalism education in China: a descriptive study of 15 Chinese programs

Thesis (M.A.)--University of Oklahoma, 2011Includes bibliographical references (leaves 78-80)

Streaming data recovery via Bayesian tensor train decomposition

In this paper, we study a Bayesian tensor train (TT) decomposition method to recover streaming data by approximating the latent structure in high-order streaming data. Drawing on the streaming variational Bayes method, we introduce the TT format into Bayesian tensor decomposition methods for streaming data, and formulate posteriors of TT cores. Thanks to the Bayesian framework of the TT format, the proposed algorithm (SPTT) excels in recovering streaming data with high-order, incomplete, and noisy properties. The experiments in synthetic and real-world datasets show the accuracy of our method compared to state-of-the-art Bayesian tensor decomposition methods for streaming data

Selling the Data Product: Pricing Strategies and Welfare Implications

This paper examines the pricing and welfare implications of data as a factor of production with a stylized economic model. We introduce a generalized framework that specifies two types of data: 1) public data pricing, which maximizes social welfare, and 2) commercial data pricing, which maximizes the profit. The model reveals two takeaways: first, two prices may converge in the data economy. It is due to that data come from citizens and may be used to create value back to them. Therefore, a profit- seeking data seller might find it optimal to extend the user base, which is in line with the interest of the welfare maximizer. Second, the pricing gap between optimal prices does not change monotonically with the improvement of data quality. These findings shed new light on the current and future of data product operations, particularly in the understudied public sectors

Caldesmon regulates the motility of vascular smooth muscle cells by modulating the actin cytoskeleton stability

<p>Abstract</p> <p>Background</p> <p>Migration of vascular smooth muscle cells (SMCs) from the media to intima constitutes a critical step in the development of proliferative vascular diseases. To elucidate the regulatory mechanism of vacular SMC motility, the roles of caldesmon (CaD) and its phosphorylation were investigated.</p> <p>Methods</p> <p>We have performed Transwell migration assays, immunofluorescence microscopy, traction microscopy and cell rounding assays using A7r5 cells transfected with EGFP (control), EGFP-wtCaD or phosphomimetic CaD mutants, including EGFP-A1A2 (the two PAK sites Ser452 and Ser482 converted to Ala), EGFP-A3A4 (the two Erk sites Ser497 and Ser527 converted to Ala), EGFP-A1234 (both PAK- and Erk-sites converted to Ala) and EGFP-D1234 (both PAK- and Erk-sites converted to Asp).</p> <p>Results</p> <p>We found that cells transfected with wtCaD, A1A2 or A3A4 mutants of CaD migrated at a rate approximately 50% more slowly than those EGFP-transfected cells. The migration activity for A1234 cells was only about 13% of control cells. Thus it seems both MAPK and PAK contribute to the motility of A7r5 cells and the effects are comparable and additive. The A1234 mutant also gave rise to highest strain energy and lowest rate of cell rounding. The migratory and contractile properties of these cells are consistent with stabilized actin cytoskeletal structures. Indeed, the A1234 mutant cells exhibited most robust stress fibers, whereas cells transfected with wtCaD or A3A4 (and A1A2) had moderately reinforced actin cytoskeleton. The control cells (transfected with EGFP alone) exhibited actin cytoskeleton that was similar to that in untransfected cells, and also migrated at about the same speed as the untransfected cells.</p> <p>Conclusions</p> <p>These results suggest that both the expression level and the level of MAPK- and/or PAK-mediated phosphorylation of CaD play key roles in regulating the cell motility by modulating the actin cytoskeleton stability in dedifferentiated vascular SMCs such as A7r5.</p