4,377 research outputs found

    Correlation among Human Resource Flexibility Strategy, Organizational Citizenship Behavior and Organizational Performance in Ecotourism Industry

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    To satisfy the demands for production peak, reduce personnel costs for labor, limit the increase of employees in enterprises, and focus on corporate specialty to develop the competitive advantage, enterprises would generally apply human resource flexibility strategy to achieve the objectives. The practice of human resource flexibility strategy would change work-related characteristics; besides, the effect of the system on employees would decide the effort, absenteeism, or turnover. Aiming at supervisors and employees in ecotourism, as the research objects, a total of 500 copies of questionnaire are distributed, and 351 valid copies are retrieved, with the retrieval rate of 70%. The research results reveal positive and significant effects of 1. human resource flexibility strategy on organizational citizenship behavior, 2. organizational citizenship behavior on organizational performance, and 3. human resource flexibility strategy on organizational performance. According to the results, suggestions are eventually proposed, expecting to provide essential assistance for the human resource flexibility strategy in ecotourism and assist in the sustainable development

    Mapping of the methylation pattern of the hMSH2 promoter in colon cancer, using bisulfite genomic sequencing

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    The detailed methylation status of CpG sites in the promoter region of hMSH2 gene has yet not to be reported. We have mapped the complete methylation status of the hMSH2 promoter, a region that contains 75 CpG sites, using bisulfite genomic sequencing in 60 primary colorectal cancers. And the expression of hMSH2 was detected by immunohistochemistry. The hypermethylation of hMSH2 was detected in 18.33% (11/60) of tumor tissues. The protein of hMSH2 was detected in 41.67% (25/60) of tumor tissues. No hypermethylation of hMSH2 was detected in normal tissues. The protein of hMSH2 was detected in all normal tissues. Our study demonstrated that hMSH2 hypermethylation and protein expression were associated with the development of colorectal cancer

    MECHANISM OF LANDING STRATERGY DURING STEP AEROBICS WITH DIFFERENT BENCH HEIGHTS AND LOADS

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    The purpose of this study was to investigate effects of different heights (6inch, 8inch, 10inch) and external loads (0% BW, 10% BW, 15% BW) on lower extremity during step aerobics. Ten college physical education students (age: 23.8 ± 2.1 years, height: 173.5 ± 6.1 cm, weight: 68.5 ± 8.0 kg) participated in this study. A Mega high-speed camera (100 Hz) and an ATMI force plate (1000Hz) were used to record kinematic and kinetic data respectively during step aerobics. Increased vertical ground reaction force, ankle movement, and decreased leg stiffness and ankle joint stiffness were found as the bench height increased to 10 inches which were considered to a high loading rates and shock to the lower extremity, especially at ankle joint. Therefore, people should avoid doing step aerobics at 10-inch bench height for a long time to protect ankle joint and soft tissue from injury

    Enhancing The Quality Of University Career Services In Taiwan: Perceptions Of University Alumni

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    An adequate supply of a high quality labor force is crucial for national economic and social well-being; consequently, nations worldwide have placed significant emphasis on university graduate employability. Nonetheless, in Taiwan, a mismatch between knowledge acquired in universities and competences required by the job market has dramatically encumbered the supply of a high quality labor force. Thus, this research endeavored to determine the major career services that should be offered in higher educational institutions to alleviate the aforementioned human resource problems.The analytic hierarchy process was adopted as the major instrument for calculating the relative importance of each career service task, and 169 university alumni working in four major career fields participated in this research. The results indicated that participants from different career fields and who graduated from different colleges at different times have very different opinions of job service requests; therefore, universities should seriously consider the differences among students and provide the necessary services for each student in line with his/her particular requests. Moreover, although almost all participants agreed that sharpening students’ job-search and interview skills was crucial in assisting students to find their first jobs, this service was extremely insufficient in universities, and universities thus have to place particular emphasis on this task in the future

    A wide-band-gap p-type thermoelectric material based on quaternary chalcogenides of Cu2ZnSnQ4 (Q=S,Se)

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    Chalcopyritelike quaternary chalcogenides, Cu(2)ZnSnQ(4) (Q=S,Se), were investigated as an alternative class of wide-band-gap p-type thermoelectric materials. Their distorted diamondlike structure and quaternary compositions are beneficial to lowering lattice thermal conductivities. Meanwhile, partial substitution of Cu for Zn creates more charge carriers and conducting pathways via the CuQ(4) network, enhancing electrical conductivity. The power factor and the figure of merit (ZT) increase with the temperature, making these materials suitable for high temperature applications. For Cu(2.1)Zn(0.9)SnQ(4), ZT reaches about 0.4 at 700 K, rising to 0.9 at 860 K

    Antimicrobial susceptibility patterns among Escherichia coli urinary isolates from community-onset health care-associated urinary tract infection

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    Urinary tract infection (UTI) is traditionally classified as community-acquired (CA) and hospital-acquired (HA). Community-onset health care-associated (HCA) infection is a new category that has gained increasing attention. The study aimed to compare the disk susceptibility of nonrepetitive Escherichia coli urinary isolates from HCA-UTI (n = 100) with that of E. coli isolates from CA-UTI (n = 85) and HA-UTI (n = 106). We found that the susceptibility pattern of HCA-UTI E. coli isolates was similar to that of HA-UTI E. coli isolates, but significantly different from that of CA-UTI E. coli isolates. In particular, the proportion of extended-spectrum β-lactamase-producing isolates was significantly higher in HCA-UTI than that in CA-UTI (30.0% vs. 3.5%, p < 0.001). We recommend that when treating HCA-UTI, it is necessary to take urine cultures for susceptibility testing to guide definite antibiotic therapy

    Macrophage M1 polarization mediated via the IL-6/STAT3 pathway contributes to apical periodontitis induced by Porphyromonas gingivalis

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    Objective: To investigate the involvement of IL-6/STAT3 signaling pathway activation in macrophage polarization and bone destruction related to apical periodontitis (AP) stimulated by Porphyromonas gingivalis. Methodology: Macrophage polarization, IL-6/STAT3 expression, and the presence of P. gingivalis were detected in human AP tissues via RT-qPCR, western blotting, and immunohistochemistry staining. Murine bone marrow derived macrophages were isolated and cultured with P. gingivalis W83 in vitro, and levels of macrophage IL-6 expression, STAT3 phosphorylation, and macrophage polarization with or without the selective STAT3 phosphorylation inhibitor Stattic (5 μM) were detected via ELISA, western blotting, RT-qPCR, and flow cytometry, respectively. P. gingivalis-induced murine AP models were constructed, and bone destruction and macrophage polarization in the apical region were evaluated. Transwell co-culture systems were used to investigate the effects of macrophages infected with P. gingivalis on osteogenesis and osteoclastogenesis. Results: P. gingivalis was detected in human AP tissues that highly expressed IL-6/STAT3, and the M1 subtype of macrophages was more abundant in these tissues. P. gingivalis infection induced IL-6 expression, STAT3 phosphorylation, and M1 polarization of macrophages, while 5 μM of Stattic partially abolished these activation effects. Systemic STAT3 blockade via oral administration of Stattic at a dose of 25 mg kg-1 alleviated murine periapical bone resorption and apical infiltration of M1 macrophages induced by P. gingivalis infection in vivo. Furthermore, macrophages infected with P. gingivalis promoted bone destruction via secretion of IL-6, TNF-α, and RANKL, which hinder pre-osteoblast expression of Runx2 and accelerate pre-osteoclast expression of NFAT2. Conclusions:The activation of IL-6/STAT3 signaling pathway is involved in mediating macrophages M1 polarization in the P. gingivalis induced apical inflammatory context and may also be intimately involved in the bone loss caused by P. gingivalis infection, directing the M1 macrophage infiltration during the progression of AP.&nbsp

    An observational and theoretical view of the radial distribution of HI gas in galaxies

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    We analyze the radial distribution of HI gas for 23 disk galaxies with unusually high HI content from the Bluedisk sample, along with a similar-sized sample of "normal" galaxies. We propose an empirical model to fit the radial profile of the HI surface density, an exponential function with a depression near the center. The radial HI surface density profiles are very homogeneous in the outer regions of the galaxy; the exponentially declining part of the profile has a scale-length of ∼0.18\sim 0.18 R1, where R1 is the radius where the column density of the HI is 1 M⊙_{\odot} pc−2^{-2}. This holds for all galaxies, independent of their stellar or HI mass. The homogenous outer profiles, combined with the limited range in HI surface density in the non-exponential inner disk, results in the well-known tight relation between HI size and HI mass. By comparing the radial profiles of the HI-rich galaxies with those of the control systems, we deduce that in about half the galaxies, most of the excess gas lies outside the stellar disk, in the exponentially declining outer regions of the HI disk. In the other half, the excess is more centrally peaked. We compare our results with existing smoothed-particle hydrodynamical simulations and semi-analytic models of disk galaxy formation in a Λ\Lambda Cold Dark Matter universe. Both the hydro simulations and the semi-analytic models reproduce the HI surface density profiles and the HI size-mass relation without further tuning of the simulation and model inputs. In the semi-analytic models, the universal shape of the outer HI radial profiles is a consequence of the {\em assumption} that infalling gas is always distributed exponentially. The conversion of atomic gas to molecular form explains the limited range of HI surface densities in the inner disk. These two factors produce the tight HI mass-size relation.Comment: 15 pages, 14 figures, submitted to MNRA

    catena-Poly[[[diaqua­terbium(III)]-μ-6-carboxy­nicotinato-μ-pyridine-2,5-di­carboxyl­ato] dihydrate]

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    The title compound, {[Tb(C7H3NO4)(C7H4NO4)(H2O)2]·2H2O}n, is isotypic with the analogous TmIII compound [Li, Zhang, Wang & Bai (2009). Acta Cryst. E65, m411]. The TbIII atom is octa­coordinated by two water mol­ecules and by four carboxyl­ate O atoms and two pyridyl N atoms from two pyridine-2,5-dicarboxyl­ate (2,5-pydc) and two 6-carboxy­nicotinate (2,5-Hpydc) ligands. The 2,5-pydc and 2,5-Hpydc ligands bridge TbIII atoms, generating helical coordination polymers along [001]. An extensive network of O—H⋯O hydrogen bonds is formed between the coordination polymers and the uncoordinated water mol­ecules. The refined Flack parameter of 0.54 (2) suggests inversion twinning
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